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See detailWhat Constitutes Aging Workforce Management? Lessons Learned in an Industry-Specific Case Study
Streb, Christoph Klaus UL; Voelpel, S; Leibold, M et al

in Bornemeyer, C; Schneider, J (Eds.) Aging Society and its Implications for Services Marketing – Approaches in Hospitality, Tourism and Transport (2011)

Detailed reference viewed: 48 (1 UL)
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See detailWhat cultural psychologies need: Generalizing theories
Valsiner, Jaan UL

in Culture & Psychology (2014)

Detailed reference viewed: 73 (0 UL)
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See detailWhat Dignity Demands: From Political to Poetical Liberalism
Mailey, Richard Samuel David UL

Doctoral thesis (2017)

The thesis attempts to measure the disjoint between the promise of human dignity that appears at the heart of Western law (e.g. in national constitutions and international human rights instruments), and ... [more ▼]

The thesis attempts to measure the disjoint between the promise of human dignity that appears at the heart of Western law (e.g. in national constitutions and international human rights instruments), and the experiences of exclusion and frustration that, in 2017, have seen many Westerners turn to anti-liberal, populist demagogues for relief. In measuring this disjoint, the thesis looks to the work of liberal and anti-liberal theorists alike, including John Rawls, Bruce Ackerman, Carl Schmitt and Jacques Derrida. It then uses the insights gained to construct a liberal theory that can overcome the key problems identified, before using this theory to critically engage with the constitutional jurisprudence of three very different states: Canada, South Africa and the United States. [less ▲]

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See detailWhat do students say about the role of the minus sign in polynominals?
Vlassis, Joëlle UL

in Proceedings of the 33rd Conference of the International Group for the Psychology of Mathematics Education (2009)

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See detailWhat do teachers think about their students' inclusion? Consistency of self- and teacher reports
Venetz; Zurbriggen, Carmen UL; Schwab, Susanne

Scientific Conference (2017, September)

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See detailWhat do teachers think about their students’ inclusion? Consistency of students’ self-reports and teacher ratings
Venetz, Martin; Zurbriggen, Carmen UL; Schwab, Susanne

in Frontiers in Psychology (2019), 10(1637), 114

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See detailWhat do we accept after an announcement?
de Boer, Mathijs UL; Herzig, Andreas; de Lima, Tiago et al

Scientific Conference (2008)

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See detailWhat Do We Know About Managing Aging Teams? Lessons Learned from the Automotive Shop Floor
Streb, Christoph Klaus UL; Gellert, F.J.

in Organizational Dynamics (2011), 40(2), 144-150

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See detailWhat Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue.
Baig, Komal UL; Ullmann, Pit UL; Rodriguez, Fabien UL et al

in PLoS ONE (2016), 11

Due to their self-renewal and tumorigenic properties, tumor-initiating cells (TICs) have been hypothesized to be important targets for colorectal cancer (CRC). However the study of TICs is hampered by the ... [more ▼]

Due to their self-renewal and tumorigenic properties, tumor-initiating cells (TICs) have been hypothesized to be important targets for colorectal cancer (CRC). However the study of TICs is hampered by the fact that the identification and culturing of TICs is still a subject of extensive debate. Floating three-dimensional spheroid cultures (SC) that grow in serum-free medium supplemented with growth factors are supposed to be enriched in TICs. We generated SC from fresh clinical tumor specimens and compared them to SC isolated from CRC cell-lines as well as to adherent differentiated counterparts. Patient-derived SC display self-renewal capacity and can induce serial transplantable tumors in immuno-deficient mice, which phenotypically resemble the tumor of origin. In addition, the original tumor tissue and established SC retain several similar CRC-relevant mutations. Primary SC express key stemness proteins such as SOX2, OCT4, NANOG and LGR5 and importantly show increased chemoresistance ability compared to their adherent differentiated counterparts and to cell line-derived SC. Strikingly, cells derived from spheroid or adherent differentiating culture conditions displayed similar self-renewal capacity and equally formed tumors in immune-deficient mice, suggesting that self-renewal and tumor-initiation capacity of TICs is not restricted to phenotypically immature spheroid cells, which we describe to be highly plastic and able to reacquire stem-cell traits even after long differentiation processes. Finally, we identified two genes among a sphere gene expression signature that predict disease relapse in CRC patients. Here we propose that SC derived from fresh patient tumor tissue present interesting phenotypic features that may have clinical relevance for chemoresistance and disease relapse and therefore represent a valuable tool to test for new CRC-therapies that overcome drug resistance. [less ▲]

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See detailWhat do we need to say about a design method?
Gericke, Kilian UL; Eckert, Claudia; Stacey, Martin

in Proceedings of the 21st International Conference on Engineering Design (2017, August)

Method development is one of the raisons d’etre of engineering design research and method uptake by industry is perceived as an important success criterion. This paper argues that one of the problems with ... [more ▼]

Method development is one of the raisons d’etre of engineering design research and method uptake by industry is perceived as an important success criterion. This paper argues that one of the problems with methods is the lack of clarity about what is actually proposed to industry and the academic community when a new method is put forward, in terms of how detailed, strict, precise and rigorous the method is and what it can deliver. This paper puts the concept of method in the context of related concepts and proposes a multi-level model of the elements of a method to argue that a contribution on each of these levels can be of value and that the introduction of methods can fail on each of these levels. Implications thereof for industry and academia are discussed, concluding that a clear description of methods and their intended use is important for enabling proper validation of each of the method’s elements and for communicating methods to academia and industry. [less ▲]

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See detail‘WHAT DO YOU MEAN YOU LOST THE PAST?’ AGENCY, EXPRESSION AND SPECTACLE IN AMATEUR FILMMAKING
Wecker, Danièle UL

Doctoral thesis (2017)

The following thesis presents an examination of privately produced amateur films taken from the Amateur Film Archive in the Centre National d’Audiovisuel in Luxembourg. It analyzes how amateur films ... [more ▼]

The following thesis presents an examination of privately produced amateur films taken from the Amateur Film Archive in the Centre National d’Audiovisuel in Luxembourg. It analyzes how amateur films present a filmic world and examines specific notions of meaning generation without meta-data and original context. Rather than take amateur film as a homogenous genre or practice, this study concentrates on film language. The first part of the following two-fold engagement with these filmic worlds thus identifies the highly differentiated filmic modes that can be read from the images. A filmic mode is related to as a concomitance of style and choice in subject matter. Without original context, these films lose their most important means of meaning generation, namely the recollective narratives that are constructed by the intended audience in the viewing situation. This work operates from a basis of analysis that takes these images as remnants of a visual narration rather than in terms of recollective narratives. It operates from the very simple basis that what was filmed had significance for these filmmakers and how the camera was used can serve as illustration of underlying intentions and motivations—both intended and inadvertent. The first part of this study then focuses on the diversification within the images and reads concomitant cultural codifications that structure representational productions in the private and also analyzes film language as means of self-inscription and self-narration. The second part of this two-fold engagement explores filmic language in terms of a visualization of primordial signifying expression coming-into-being. It relates to amateur film and practice from a basis of primary Becoming rather than a fixed Being. This engagement extends to include the researcher and his/her own background as co-constitutive part of this process of primordial meaning coming-into-being. Film is related to as the opening of a filmic universe that presents its own structures and engagements and not as visualization of a profilmic world from the past. [less ▲]

Detailed reference viewed: 77 (18 UL)
See detailWhat does it take to learn from one’s life? Exploring opportunities for biographical learning in the lifecourse.
Tedder, M.; Biesta, Gert UL

in Merrill, B. (Ed.) Learning to Change? The Role of Identity and Learning Careers in Adult Education. (2009)

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See detailWhat Drives Exchange Rates? Reassessing Currency Return Predictability
Ferreira Filipe, Sara UL; Maio, Paulo

E-print/Working paper (2015)

We compute a variance decomposition for the log exchange rate based on a present-value relation. At long horizons, return predictability drives the variation in the exchange rate while predictability of ... [more ▼]

We compute a variance decomposition for the log exchange rate based on a present-value relation. At long horizons, return predictability drives the variation in the exchange rate while predictability of future interest rate differentials plays a secondary role. At shorter horizons, the dominant source is predictability of the future spot rate. There is more return predictability and less interest spread and exchange rate predictability in the case of real exchange rates compared to nominal exchange rates. An alternative decomposition based on a first-order VAR tends to overstate the importance of predictability of future interest spreads and exchange rates. [less ▲]

Detailed reference viewed: 116 (1 UL)
See detailWhat Drives Inequality
Decancq, Koen; van Kerm, Philippe UL

Book published by Emerald Publishing Ltd (2019)

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See detailWhat drives the development of social inequality over the life course? The German TwinLife study
Hahn, E.; Gottschling, Juliana UL; Bleidorn, W. et al

in Twin Research and Human Genetics (2016), 19

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See detailWhat enhances the Life Satisfaction of postgraduates who studied in Luxembourg, in the EU or out-EU universities?
Karathanasi, Chrysoula UL; Odero, Angela UL; Karavdic, Senad et al

in Papanikos, Gregori. T. (Ed.) Education (2016)

Postgraduate students’ Life Satisfaction (LS) has been few explored, in a context where mobility towards universities abroad is increasing. In Luxembourg, more than half of students pursue their studies ... [more ▼]

Postgraduate students’ Life Satisfaction (LS) has been few explored, in a context where mobility towards universities abroad is increasing. In Luxembourg, more than half of students pursue their studies in a different country, and must be able to cope with this transition. Our research questions were (1) which factors are associated with students’ LS, according to their country of studies, and in relation to their mental health, career attitude and socioeconomic characteristics? and (2) which determinants contribute to a better LS for each group? For the years 2012 and 2013, all postgraduates who had obtained a financial aid from the Luxembourgish government were contacted by post to complete an online questionnaire. For the 492 respondents, the regression analysis showed that a higher health satisfaction leads to higher LS. Career optimism and planning were positively associated with LS for students in Luxembourg. Higher were autonomy and career adaptability, and lower was worry, better was the LS for those studying in EU. To enhance students’ LS, it is suggested a preparation for a successful mobility organized by the corresponding CEDIES of every country. Moreover, an accompaniment realized by the hosting university should be also proposed to students in mobility. [less ▲]

Detailed reference viewed: 121 (13 UL)