Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailPrehistoric genomes reveal the genetic foundation and cost of horse domestication.
Schubert, Mikkel; Jonsson, Hakon; Chang, Dan et al

in Proceedings of the National Academy of Sciences of the United States of America (2014), 111(52), 5661-9

The domestication of the horse approximately 5.5 kya and the emergence of mounted riding, chariotry, and cavalry dramatically transformed human civilization. However, the genetics underlying horse ... [more ▼]

The domestication of the horse approximately 5.5 kya and the emergence of mounted riding, chariotry, and cavalry dramatically transformed human civilization. However, the genetics underlying horse domestication are difficult to reconstruct, given the near extinction of wild horses. We therefore sequenced two ancient horse genomes from Taymyr, Russia (at 7.4- and 24.3-fold coverage), both predating the earliest archeological evidence of domestication. We compared these genomes with genomes of domesticated horses and the wild Przewalski's horse and found genetic structure within Eurasia in the Late Pleistocene, with the ancient population contributing significantly to the genetic variation of domesticated breeds. We furthermore identified a conservative set of 125 potential domestication targets using four complementary scans for genes that have undergone positive selection. One group of genes is involved in muscular and limb development, articular junctions, and the cardiac system, and may represent physiological adaptations to human utilization. A second group consists of genes with cognitive functions, including social behavior, learning capabilities, fear response, and agreeableness, which may have been key for taming horses. We also found that domestication is associated with inbreeding and an excess of deleterious mutations. This genetic load is in line with the "cost of domestication" hypothesis also reported for rice, tomatoes, and dogs, and it is generally attributed to the relaxation of purifying selection resulting from the strong demographic bottlenecks accompanying domestication. Our work demonstrates the power of ancient genomes to reconstruct the complex genetic changes that transformed wild animals into their domesticated forms, and the population context in which this process took place. [less ▲]

Detailed reference viewed: 108 (2 UL)
Full Text
Peer Reviewed
See detailPreimplantation development regulatory pathway construction through a text-mining approach.
Donnard, Elisa; Barbosa Da Silva, Adriano UL; Guedes, Rafael L. M. et al

in BMC genomics (2011), 12 Suppl 4

BACKGROUND: The integration of sequencing and gene interaction data and subsequent generation of pathways and networks contained in databases such as KEGG Pathway is essential for the comprehension of ... [more ▼]

BACKGROUND: The integration of sequencing and gene interaction data and subsequent generation of pathways and networks contained in databases such as KEGG Pathway is essential for the comprehension of complex biological processes. We noticed the absence of a chart or pathway describing the well-studied preimplantation development stages; furthermore, not all genes involved in the process have entries in KEGG Orthology, important information for knowledge application with relation to other organisms. RESULTS: In this work we sought to develop the regulatory pathway for the preimplantation development stage using text-mining tools such as Medline Ranker and PESCADOR to reveal biointeractions among the genes involved in this process. The genes present in the resulting pathway were also used as seeds for software developed by our group called SeedServer to create clusters of homologous genes. These homologues allowed the determination of the last common ancestor for each gene and revealed that the preimplantation development pathway consists of a conserved ancient core of genes with the addition of modern elements. CONCLUSIONS: The generation of regulatory pathways through text-mining tools allows the integration of data generated by several studies for a more complete visualization of complex biological processes. Using the genes in this pathway as "seeds" for the generation of clusters of homologues, the pathway can be visualized for other organisms. The clustering of homologous genes together with determination of the ancestry leads to a better understanding of the evolution of such process. [less ▲]

Detailed reference viewed: 120 (2 UL)
Full Text
Peer Reviewed
See detailPréjudice causé par le dépassement d'un mandat de gestion, Note sous Cass. com., 6 déc. 2017
Riassetto, Isabelle UL

in Revue de Droit Bancaire et Financier (2018)

Detailed reference viewed: 78 (5 UL)
Full Text
Peer Reviewed
See detailLe préjugement au fond comme critère de partialité objective
Menetrey, Séverine UL

in Recueil Dalloz (2013)

Detailed reference viewed: 80 (1 UL)
Full Text
Peer Reviewed
See detailA preliminary assessment of the effects of migration on the production structure in Europe: A labor task approach
Joxhe, Majlinda UL; De Arcangelis, Giuseppe; Borelli, Stefania

in Economics Bulletin (2019), 39(1), 289-294

We assess the e ffect of migration on the production structure in a selection of European countries for the pre-Great Recession period 2001-2009. We propose a labor-task approach where the inflow of ... [more ▼]

We assess the e ffect of migration on the production structure in a selection of European countries for the pre-Great Recession period 2001-2009. We propose a labor-task approach where the inflow of migrants raises the relative supply of manual-physical (or simple) tasks and therefore favors simple-task intensive sectors. We use the US O*NET database in conjunction with European labor data to calculate the index of simple-task intensity at the industry and country level. The analysis confi rms that a rise in employment migration rates has a generalized positive impact, but that value-added increases signi ficantly more in sectors that use more intensively simple tasks. A traditional shift-share instrument is used to overcome possible endogeneity problems. [less ▲]

Detailed reference viewed: 45 (4 UL)
See detailThe Preliminary Criminal Procedure in Luxembourg
Petschko, Martin UL; Schiltz, Marc; Tosza, Stanislaw UL

in Ligeti, Katalin (Ed.) Toward a Prosecutor for the European Union (2013)

Detailed reference viewed: 138 (25 UL)
Full Text
See detailPreliminary findings: EMN-OECD InformDigitalisation and Artificial Intelligence
Sommarribas, Adolfo UL

Scientific Conference (2022, January 27)

This presentation provides the preliminary findings of the EMN-OECD Inform on Digitalisation and Artificial Intelligence. It aims to analyse the use of digitalisation and artificial intelligence in ... [more ▼]

This presentation provides the preliminary findings of the EMN-OECD Inform on Digitalisation and Artificial Intelligence. It aims to analyse the use of digitalisation and artificial intelligence in migration management. [less ▲]

Detailed reference viewed: 70 (1 UL)
Full Text
Peer Reviewed
See detailA preliminary investigation of the growth of an aneurysm with a multiscale monolithic Fluid-Structure interaction solver
Cerroni, D.; Manservisi, S.; Pozzetti, Gabriele UL

in Journal of Physics: Conference Series (2015), 655(1), 012050

In this work we investigate the potentialities of multi-scale engineering techniques to approach complex problems related to biomedical and biological fields. In particular we study the interaction ... [more ▼]

In this work we investigate the potentialities of multi-scale engineering techniques to approach complex problems related to biomedical and biological fields. In particular we study the interaction between blood and blood vessel focusing on the presence of an aneurysm. The study of each component of the cardiovascular system is very difficult due to the fact that the movement of the fluid and solid is determined by the rest of system through dynamical boundary conditions. The use of multi-scale techniques allows us to investigate the effect of the whole loop on the aneurysm dynamic. A three-dimensional fluid-structure interaction model for the aneurysm is developed and coupled to a mono-dimensional one for the remaining part of the cardiovascular system, where a point zero-dimensional model for the heart is provided. In this manner it is possible to achieve rigorous and quantitative investigations of the cardiovascular disease without loosing the system dynamic. In order to study this biomedical problem we use a monolithic fluid-structure interaction (FSI) model where the fluid and solid equations are solved together. The use of a monolithic solver allows us to handle the convergence issues caused by large deformations. By using this monolithic approach different solid and fluid regions are treated as a single continuum and the interface conditions are automatically taken into account. In this way the iterative process characteristic of the commonly used segregated approach, it is not needed any more. [less ▲]

Detailed reference viewed: 189 (35 UL)
Full Text
Peer Reviewed
See detailPreliminary investigation on the capability of eXtended Discrete Element method for treating the dripping zone of a blast furnace
Baniasadi, Maryam UL; Peters, Bernhard UL

in ISIJ International (2017), 58(1),

The role of molten iron and slag in the dripping zone of a blast furnace is very critical to reach a stable operational condition. The existence of several fluid phases and solid particles in the dripping ... [more ▼]

The role of molten iron and slag in the dripping zone of a blast furnace is very critical to reach a stable operational condition. The existence of several fluid phases and solid particles in the dripping zone of a blast furnace, makes the newly developed eXteneded Discrete Element Method (XDEM) as an Eulerian-Lagrangian approach, suitable to resolve the dripping zone of a blast furnace. In the proposed model, the fluid phases are treated by Computational Fluid Dynamics (CFD) while the solid particles are solved by Discrete Element Method (DEM). These two methods are coupled via momentum, heat and mass exchanges. The main focus of current study is to investigate the influence of packed properties such as porosity and particle diameters, calculated by the XDEM, on the fluid phases for isothermal. In order to present the capability of the XDEM for this application. The validity of the proposed model is demonstrated by comparing model prediction results with the available experimental data. [less ▲]

Detailed reference viewed: 143 (11 UL)
Full Text
See detailPreliminary results of the BIPM Relative Gravity Measurement Campaign during the 8th International Comparison of Absolute Gravimeters (2009)
Jiang, Zihang; Tisserand, L.; Kessler-Schulz, K. U. et al

in Peshekhonov, Vladimir (Ed.) Proceedings of the IAG Symposium on Terrestrial Gravimetry: Static and Mobile Measurements (2011)

Detailed reference viewed: 87 (6 UL)
Full Text
Peer Reviewed
See detailA Preliminary Study on the Automatic Visual based Identification of UAV Pilots from Counter UAVs
Cazzato, Dario; Cimarelli, Claudio UL; Voos, Holger UL

in 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 5: VISAPP, Valletta 27-29 February 2020 (2020, February 27)

Two typical Unmanned Aerial Vehicles (UAV) countermeasures involve the detection and tracking of the UAV position, as well as of the human pilot; they are of critical importance before taking any ... [more ▼]

Two typical Unmanned Aerial Vehicles (UAV) countermeasures involve the detection and tracking of the UAV position, as well as of the human pilot; they are of critical importance before taking any countermeasure, and they already obtained strong attention from national security agencies in different countries. Recent advances in computer vision and artificial intelligence are already proposing many visual detection systems from an operating UAV, but they do not focus on the problem of the detection of the pilot of another approaching unauthorized UAV. In this work, a first attempt of proposing a full autonomous pipeline to process images from a flying UAV to detect the pilot of an unauthorized UAV entering a no-fly zone is introduced. A challenging video sequence has been created flying with a UAV in an urban scenario and it has been used for this preliminary evaluation. Experiments show very encouraging results in terms of recognition, and a complete dataset to evaluate artificial intelligence-based solution will be prepared. [less ▲]

Detailed reference viewed: 98 (1 UL)
Full Text
Peer Reviewed
See detailA PRELIMINARY STUDY ON THE STABILITY OF PARTICLE LADEN JETS THROUGH A FULLY COUPLED CFD-DEM SOLVER
Peters, Bernhard UL; Pozzetti, Gabriele UL

Poster (2016, May 22)

Jets are widely used in engineering applications. In material machinery, hydro-transportation systems as well as in chemical industry it is common to deal with a dispersed solid phase interacting with the ... [more ▼]

Jets are widely used in engineering applications. In material machinery, hydro-transportation systems as well as in chemical industry it is common to deal with a dispersed solid phase interacting with the jet, and therefore creating a so-called slurry-jet or particle-laden jet. The stability of a jet is a key issue for many of these processes, still the underlying physics of this turbulent multiphase flow is highly complicated. Conventional CFD approaches have been proven satisfying for the study of the stability of two-phase jets. When a solid dispersed phase is present in the system, the stability problem gets more complicated and dependent on the solid phase dynamic. A possible solution for the problem is to extend the CFD solver capability through a correct coupling with a DEM solver. In this work a preliminary investigation on the potentialities of this kind of approach is presented and compared with a pure CFD approach. In particular the effect of the presence of differently sized particles in the jet is outlined and the influence of particle properties and concentration is investigated. Finally some considerations about the computational cost of different methods are proposed. The fluid phases are solved through an Eulerian finite volume (FV) multiphase solver based on the OpenFoam® libraries, and coupled with the XDEM code in order to treat the dispersed phase in a Lagrangian way. [less ▲]

Detailed reference viewed: 179 (20 UL)
Peer Reviewed
See detail«Premessa»
Roelens, Nathalie UL

in Piccole finizioni con importanza. Valori della narrativa italiana contemporanea (1993)

Detailed reference viewed: 42 (1 UL)
Full Text
See detailPremier bilan d'un débat national
Pauly, Michel UL

in Vincent ARTUSO, La « question juive » au Luxembourg (1933-1941). L’Etat luxembourgeois face aux persécutions antisémites nazies. Rapport final (2015)

Avant-propos dressant un bilan provisoire du débat autour du 'rapport Artuso' sur l'attitude de la Commission administrative de 1940 la question juive au Luxembourg

Detailed reference viewed: 67 (2 UL)
Full Text
Peer Reviewed
See detailPremier et deuxième espaces de cohomologie de l'algèbre de Lie des opérateurs différentiels sur une variété à coefficients dans les fonctions
Poncin, Norbert UL

in Bulletin de la Société Royale des Sciences de Liège (1998), 67(6), 291--337

Detailed reference viewed: 57 (5 UL)
Peer Reviewed
See detailPremier regard sur l’éducation familiale au Luxembourg et les relations école-famille.
Poncelet, Débora UL; Kerger, Sylvie UL; Dierendonck, Christophe UL

in catarsi, enzo; pourtois, jp (Eds.) Les formations et les recherches en éducation familiale (2011)

Detailed reference viewed: 80 (3 UL)