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See detailDie Textilindustrie in der Großregion SaarLorLux
Edelblutte, Simon; Pauly, Michel UL; Caruso, Geoffrey UL et al

E-print/Working paper (2012)

Die Textilindustrie hatte sehr viel Zeit um die Industrielandschaften der Großregion zu verändern, denn sie ist eine der sehr frühzeitig industrialisierten wirtschaftlichen Aktivitäten. Sie entstand oft ... [more ▼]

Die Textilindustrie hatte sehr viel Zeit um die Industrielandschaften der Großregion zu verändern, denn sie ist eine der sehr frühzeitig industrialisierten wirtschaftlichen Aktivitäten. Sie entstand oft auf proto-industrieller Basis, wurde bereits sehr früh in fast all ihren Sektoren mechanisiert (von der Spinnerei über die Weberei, das Färben, das Bleichen und das Bedrucken bis hin zur Konfektion) und lässt auf diese Art manchmal große Industriezusammenschlüsse entstehen, die neben bescheidener gebliebenen Niederlassungen beeindrucken. Dieser Pioniersektor wird heute in Europa oft als Aktivität der Vergangenheit angesehen, deren wichtigste Bereiche in südliche Länder mit billigeren Arbeitskräften ausgelagert wurden. Doch auch wenn die Textilindustrie in der Großregion ein Bild von mehr oder weniger gut umgewandelten und im Sinne des kulturellen Erbes zur Geltung gebrachten Hinterlassenschaften abgibt, so ist sie auch und noch immer ein aktiver Sektor, orientiert in Richtung industrieller Marktnischen oder der Herstellung hochwertiger Produkte. Diese innovativen Produktionen erfolgen oft in modernen Gebäuden, die sich abheben vom Klischee der Textilfabriken in Shedbauweise mit auffallenden hohen Backsteinschloten. [less ▲]

Detailed reference viewed: 53 (1 UL)
See detailTextmosaiken. Fontane, Kleist und das „Käthchen“.
Amann, Wilhelm UL

in Ernst, Thomas; Mein, Georg (Eds.) Literatur als Interdiskurs. Realismus und Normalismus, Interkulturalität und Intermedialität von der Moderne bis zur Gegenwart. Eine Festschrift für Rolf Parr zum 60. Geburtstag. (2016)

Detailed reference viewed: 37 (0 UL)
See detailTextreproduktion: e) Schallaufzeichnung
Dembeck, Till UL

in Binczek, Natalie; Dembeck, Till; Schäfer, Jörgen (Eds.) Handbuch Medien der Literatur (2013)

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See detailTextual Inference with Deep Learning Technique
Adebayo, Kolawole; Di Caro, Luigi; Robaldo, Livio UL et al

in Proc. of the 28th Annual Benelux Conference on Artificial Intelligence (BNAIC2016). (2016)

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See detailTextuality of Italian Migration in Luxembourg and the Great Region
Cicotti, Claudio UL

in The Italian American Review (2012), 2(2), 79-95

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See detailTHAP1, the gene mutated in DYT6 dystonia, autoregulates its own expression.
Erogullari, Alev; Hollstein, Ronja; Seibler, Philip et al

in Biochimica et biophysica acta (2014), 1839(11), 1196-204

THAP1 encodes a transcription factor but its regulation is largely elusive. TOR1A was shown to be repressed by THAP1 in vitro. Notably, mutations in both of these genes lead to dystonia (DYT6 or DYT1 ... [more ▼]

THAP1 encodes a transcription factor but its regulation is largely elusive. TOR1A was shown to be repressed by THAP1 in vitro. Notably, mutations in both of these genes lead to dystonia (DYT6 or DYT1). Surprisingly, expressional changes of TOR1A in THAP1 mutation carriers have not been detected indicating additional levels of regulation. Here, we investigated whether THAP1 is able to autoregulate its own expression. Using in-silico prediction, luciferase reporter gene assays, and (quantitative) chromatin immunoprecipitation (ChIP), we defined the THAP1 minimal promoter to a 480bp-fragment and demonstrated specific binding of THAP1 to this region which resulted in repression of the THAP1 promoter. This autoregulation was disturbed by different DYT6-causing mutations. Two mutants (Ser6Phe, Arg13His) were shown to be less stable than wildtype THAP1 adding to the effect of reduced binding to the THAP1 promoter. Overexpressed THAP1 is preferably degraded through the proteasome. Notably, endogenous THAP1 expression was significantly reduced in cells overexpressing wildtype THAP1 as demonstrated by quantitative PCR. In contrast, higher THAP1 levels were detected in induced pluripotent stem cell (iPS)-derived neurons from THAP1 mutation carriers. Thus, we identified a feedback-loop in the regulation of THAP1 expression and demonstrated that mutant THAP1 leads to higher THAP1 expression levels. This compensatory autoregulation may contribute to the mean age at onset in the late teen years or even reduced penetrance in some THAP1 mutation carriers. [less ▲]

Detailed reference viewed: 88 (4 UL)
See detailThat Escalated Quickly: The Cyber-ASAT Conundrum
Blount, Percy UL

in Blount, Percy; Masson-Zwaan, Tanja; Moro-Aguilar, Rafael (Eds.) et al 2018 Proceedings of the IISL (2019)

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See detailThat Troublesome Knot between Ethics and Aesthetics : ‘Resistant Art’
Tore, Gian Maria UL

in Keep Your Feelings in Memory (catalogue d’art de l’Agence Borderline, Luxembourg) (2014)

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See detail“That’s a value I would transmit in some way, but how concretely, I don’t know” – Intergenerational value transfer revisited in light of memory
Albert, Isabelle UL; Barros, Stephanie; Boulanger, Dany

in Wagoner, Brady; Bresco, I.; Zadeh, S. (Eds.) Memory in the Wild (in press)

Intergenerational value transmission occurs widely and to a large extent within the family as primary socialization agent. In families, children are confronted with specific practices, paradigms, rules ... [more ▼]

Intergenerational value transmission occurs widely and to a large extent within the family as primary socialization agent. In families, children are confronted with specific practices, paradigms, rules and routines which are part of their family culture (Albert & Barros Coimbra, 2017) and as such family is a mediator between societal/cultural and individual values. The ability to transmit values is essential for collective knowledge and memory, the continuity of value orientations being a main feature of intergenerational relations that enables members of different generations to communicate with each other (Barni, Rosnati, & Ranieri, 2013; Halbwachs, 1941/1992; Schönpflug, 2001). Intergenerational transmission of values becomes particularly complex in the context of migration or in times of rapid social change. On the one hand, family identity and traditions might provide a secure base in light of a changing context, and parents might find it important to transmit traditional values to the next generation in order to keep memories alive. At the same time, they might feel that their children should adapt to the changed cultural context, resulting in a (not always clear) dilemma about what they want for their children. How can migrant parents reconcile or move between the different collective frameworks of their culture of origin and the receiving culture (Middleton & Brown, 2005)? In the following, we will first give a brief overview over research in the area of intergenerational value transmission, and we will second illustrate and further inform our theoretical assumptions by identifying related themes and phenomena in our qualitative dyadic interviews. Then, we will delve into memory as a horizon that is emerging out of the analysis as a transversal theme. From this point of view, we continue the analysis and progressively integrate the notions pertaining to the role of memory in the intergenerational transmission of values. Aspects of cultural background are apparent in the excerpts that we will quote supporting the themes we will refer to. We will more explicitly return to this in our conclusions. [less ▲]

Detailed reference viewed: 57 (1 UL)
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See detailThe City as a Terminal. Der technisch-­organisatorische Wandel der Logistik und seine Bedeutung für die Städte
Hesse, Markus UL

in Dienel, Hans-Liudger; Schiedt, Hans-Ulrich (Eds.) Die moderne Straße: Planung, Bau und Verkehr vom 18. bis zum 20. Jahrhundert (2010)

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See detailThe Country of Origin Principle From State Sovereignty under Public International Law to Inclusion in the Audiovisual Media Services Directive of the European Union
Cole, Mark UL

in Meng, Werner; Ress, Georg; Stein, Torsten (Eds.) Europäische Integration und Globalisierung – Festschrift zum 60-jährigen Bestehen des Europa-Instituts (2011)

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See detailThe Effect of the German Accounting Law Modernization Act (BilMoG) on the Earnings Quality of Private Firms
Lopatta, Kerstin UL; Kaspereit, Thomas UL; Jaeschke, Reemda et al

in Corporate Finance (2013), (5), 234-242

The 2009 Accounting Law Modernization Act (BilMoG) had a considerable impact on German accounting principles, especially in terms of tax regulations, recognition, and measurement options. This paper ... [more ▼]

The 2009 Accounting Law Modernization Act (BilMoG) had a considerable impact on German accounting principles, especially in terms of tax regulations, recognition, and measurement options. This paper analyzes whether these changes have had a positive effect on the quality of earnings reported in German financial statements. We find that earnings management significantly decreased after the implementation of BilMoG. This study is the first to examine potential improvements on earnings quality as a result of BilMoG. Our results indicate that in the run-up to the reform, legislators effectively aligned domestic accounting standards with IFRS principles, which led to improved transparency within financial reporting. [less ▲]

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See detailThe Equational Approach to Contrary-to-duty Obligations
Gabbay, Dov M. UL

in Beierle, Christoph; Meghini, Carlo (Eds.) Foundations of Information and Knowledge Systems (2014)

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See detailThe Evolution of Erythrocytes Becoming Red in Respect to Fluorescence
Hertz, Laura; Ruppenthal, Sandra; Simionato, Greta et al

in FRONTIERS IN PHYSIOLOGY (2019), 10

Very young red blood cells, namely reticulocytes, can be quite easily recognized and labeled by cluster of differentiation antibodies (CD71 transferrin receptor) or by staining remnant RNA with thiazol ... [more ▼]

Very young red blood cells, namely reticulocytes, can be quite easily recognized and labeled by cluster of differentiation antibodies (CD71 transferrin receptor) or by staining remnant RNA with thiazol orange. In contrast, age specific erythrocyte labeling is more difficult in later periods of their life time. While erythrocytes contain band 4.1 protein a molecular clock, so far it has not been possible to read this clock on individual cells. One concept to track erythrocytes during their life time is to mark them when they are young, either directly in vivo or ex vivo followed by a transfusion. Several methods like biotinylation, use of isotopes or fluorescent labeling have proved to be useful experimental approaches but also have several inherent disadvantages. Genetic engineering of mice provides additional options to express fluorescent proteins in erythrocytes. To allow co-staining with popular green fluorescent dyes like Fluo-4 or other fluorescein-based dyes, we bred a mouse line expressing a tandem red fluorescent protein (tdRFP). Within this Brief Research Report, we provide the initial characterisation of this mouse line and show application examples ranging from transfusion experiments and intravital microscopy to multicolour flow cytometry and confocal imaging. We provide a versatile new tool for erythrocyte research and discuss a range of experimental opportunities to study membrane processes and other aspects of erythrocyte development and aging with help of these animals. [less ▲]

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See detailThe History of the Russian Worker Colony in Wiltz in 1920s-1930s
Ganschow, Inna UL

Speeches/Talks (2019)

The guided tour in Wiltz and especially at the former leather factory "Ideal", where around 200 Russian migrants were working in the 1920s-1930s, was offered for the young Russian speaking audience of ... [more ▼]

The guided tour in Wiltz and especially at the former leather factory "Ideal", where around 200 Russian migrants were working in the 1920s-1930s, was offered for the young Russian speaking audience of scouts. Besides the historical context and the view on the migration "from outside" the tour offered a meeting with a descendant of the Russian emigrants in Wiltz and gave the possibility to hear about the migration from "within". [less ▲]

Detailed reference viewed: 59 (4 UL)