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See detailLe tandem au service de l’intégration académique
Lejot, Eve UL; Molostoff, Leslie UL

in Synergies Portugal (2019), 7

Each semester, the University of Luxembourg Languages Centre offers multilingual classes and standalone events in the university’s three official languages: French, German and English. The tandem learning ... [more ▼]

Each semester, the University of Luxembourg Languages Centre offers multilingual classes and standalone events in the university’s three official languages: French, German and English. The tandem learning programme attracted 104 students in the academic year 2018-2019. Student feedback shows that they expect the tandem learning programme to help them integrate academically. Our goal now is to provide lasting support throughout their university life via tandem learning based on the principal of knowledge sharing. This knowledge sharing is made possible via the available interdisciplinary academic educational resources. [less ▲]

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See detailTandems patient-aidant face au retentissement familial et social deux ans après la survenue d’un AVC au Grand-duché de Luxembourg
Baumann, Michèle UL; Kovincic, P.; Le Bihan, Etienne UL

in Sociologie de la Santé (2009)

Notre problématique s’inscrit dans l’identification et la compréhension des conséquences que peut avoir la survenue d’un accident cérébro-vasculaire sur la famille et les proches de la personne qui en a ... [more ▼]

Notre problématique s’inscrit dans l’identification et la compréhension des conséquences que peut avoir la survenue d’un accident cérébro-vasculaire sur la famille et les proches de la personne qui en a été victime. En effet, l’AVC produit des effets sur l’organisation des relations entre les patients et les aidants, ce réaménagement dépendant en grande partie de la situation antérieure des liens affectifs. La personne atteinte de plein fouet par cet accident n’est pas la seule au centre de cette étude, nous avons fait le choix de privilégier également la personne désignée par le patient comme son « aidant principal ». Au sein des tandems patient-aidant qui partagent désormais le quotidien entaché des conséquences produites par un AVC, s’installe ou non une harmonie en fonction de la manière dont l’évènement est ressenti et intériorisé. La façon dont le patient et l’aidant vivent l’adaptation à cette nouvelle situation et la façon dont les personnes rencontrées réagissent devant les comportements de la personne atteinte font appels ou non à une complicité qui mérite d’être étudiée. Face au retentissement psychologique et social, aux activités culturelles et de loisirs abandonnées ou maintenues, aux aides, services et informations obtenus ou non depuis l’AVC, les objectifs de ce travail ont été de comparer les réponses fournies par les patients et les aidants et d’analyser les domaines dans lesquels elles sont concordantes au sein des diades. [less ▲]

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See detailTankstellen als Zwischenräume I: Praktiken und Narrative
Kmec, Sonja UL

in Wille, Christian; Reckinger, Rachel; Kmec, Sonja (Eds.) et al Räume und Identitäten in Grenzregionen. Politiken – Medien – Subjekte (2014)

Dieser Beitrag untersucht Tankstellen als ein räumliches Element, das auf der einen Seite Luxemburgs staatliche Grenzen - und somit das Image des Landes selbst - prägt. Auf der anderen Seite haben ... [more ▼]

Dieser Beitrag untersucht Tankstellen als ein räumliches Element, das auf der einen Seite Luxemburgs staatliche Grenzen - und somit das Image des Landes selbst - prägt. Auf der anderen Seite haben Tankstellen mit anderen Orten anonymen Massentransits (wie Bahnhöfen, Flughäfen oder Supermärkten) gemein, dass sie »keine besondere Identität und kein besonderes Verhältnis, sondern Einsamkeit und Ähnlichkeit« schaffen. Sie entsprechen Marc Augés Beschreibung von »wirklichen Nicht-Orten der Übermoderne«. »Nicht-Orte« werden dabei nicht ontologisch definiert, d.h. nicht als Dinge an sich, sondern im Kontrast zum »relationalen« Charakter von »Orten«. Dieser Beitrag zeigt auf, wie Tankstellen - in Darstellung und Praxis - zwischen der Sphäre der Unpersönlichkeit und jener der Vertrautheit oszillieren und inwiefern dadurch neue Räume für (Inter-)Aktion eröffnen werden. [less ▲]

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See detailTankstellen als Zwischenräume II: Transfiguration
Prüm, Agnès UL

in Wille, Christian; Reckinger, Rachel; Kmec, Sonja (Eds.) et al Räume und Identitäten in Grenzregionen. Politiken – Medien – Subjekte (2014)

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See detailTanktourismus in der Großregion SaarLorLux
Ullrich, Daniel; Pauly, Michel UL; Caruso, Geoffrey UL et al

E-print/Working paper (2009)

Das Großherzogtum Luxemburg verfügte im Jahr 2008 über 238 Tankstellen. Allein 167 davon - knapp drei Viertel - liegen in unmittelbarer Nähe zur Landesgrenze. Hier kam es in den letzten Jahrzehnten zu ... [more ▼]

Das Großherzogtum Luxemburg verfügte im Jahr 2008 über 238 Tankstellen. Allein 167 davon - knapp drei Viertel - liegen in unmittelbarer Nähe zur Landesgrenze. Hier kam es in den letzten Jahrzehnten zu einer unverhältnismäßig hohen Konzentration von Tankstellen als Folge des internationalen Tanktourismus, eines Phänomens, das sich aus dem deutlichen Preisvorteil des Kraftstoffs in Luxemburg gegenüber seinen Nachbarländern ergibt. [less ▲]

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See detailTanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models
Buenafe, O. E.; Orellana-Paucar, A.; Maes, J. et al

in ACS Chemical Neuroscience (2013), 4(11), 1479-1487

Danshen or Chinese red sage (Salvia miltiorrhiza, Bunge) is used by traditional Chinese medicine (TCM) practitioners to treat neurological, cardiovascular, and cerebrovascular disorders and is included in ... [more ▼]

Danshen or Chinese red sage (Salvia miltiorrhiza, Bunge) is used by traditional Chinese medicine (TCM) practitioners to treat neurological, cardiovascular, and cerebrovascular disorders and is included in some TCM formulations to control epileptic seizures. In this study, acetonic crude extracts of danshen inhibited pentylenetetrazol (PTZ)-induced seizure activity in zebrafish larvae. Subsequent zebrafish bioassay-guided fractionation of the extract resulted in the isolation of four major tanshinones, which suppressed PTZ-induced activity to varying degrees. One of the active tanshinones, tanshinone IIA, also reduced c-fos expression in the brains of PTZ-exposed zebrafish larvae. In rodent seizure models, tanshinone IIA showed anticonvulsive activity in the mouse 6-Hz psychomotor seizure test in a biphasic manner and modified seizure thresholds in a complex manner for the mouse i.v. PTZ seizure assay. Interestingly, tanshinone IIA is used as a prescription drug in China to address cerebral ischemia in patients. Here, we provide the first in vivo evidence demonstrating that tanshinone IIA has anticonvulsant properties as well. © 2013 American Chemical Society. [less ▲]

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See detailTanz um den weißen Stier. Europa und das Theater der Gegenwart
Tropper, Elisabeth UL

Speeches/Talks (2016)

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See detailTanz um den weißen Stier. Europa und das Theater der Gegenwart. Zur Einführung in ein weites Feld
Tropper, Elisabeth UL

in Bloch, Natalie; Heimböckel, Dieter; Tropper, Elisabeth (Eds.) Vorstellung Europa - Performing Europe. Interdisziplinäre Perspektiven auf Europa im Theater der Gegenwart (2017)

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See detailTAO4school: Generic goes specific
Fischbach, Antoine UL

Bachelor/master dissertation (2008)

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See detailTAO: Paving the Way New Assessment Instruments using an open and versatile Computer-Based Platform
Latour, Thibaud; Martin, Romain UL; Plichart, P. et al

in International Journal of Psychology (2008), 43

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See detailTAO: Several use cases of a collaborative, internet-based computer-assisted testing platform
Martin, Romain UL; Latour, T.; Burton, Réginald UL et al

in Proceedings of world conference on educational multimedia, hypermedia and telecommunications 2006 (2006)

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See detailTapping the Potential of Diverse Founding Teams for Firm Growth: The Role of New Venture Activities
Tryba, Anne UL; Patzelt, Holger; Breugst, Nicola

Scientific Conference (2018, August)

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See detailTarget setting in intensive insulin management is associated with metabolic control: The Hvidoere Childhood Diabetes Study Group Centre Differences Study 2005
Swift, P. G. F.; Skinner, T. C.; De Beaufort, Carine UL et al

in Pediatric Diabetes (2010), 11(4), 271-278

Objective: To evaluate glycaemic targets set by diabetes teams, their perception by adolescents and parents, and their influence on metabolic control.Methods: Clinical data and questionnaires were ... [more ▼]

Objective: To evaluate glycaemic targets set by diabetes teams, their perception by adolescents and parents, and their influence on metabolic control.Methods: Clinical data and questionnaires were completed by adolescents, parents/carers and diabetes teams in 21 international centres. HbA1c was measured centrally.Results: A total of 2062 adolescents completed questionnaires (age 14.4 ± 2.3 yr; diabetes duration 6.1 ± 3.5 yr). Mean HbA 1c = 8.2 ± 1.4% with significant differences between centres (F = 12.3; p < 0.001) range from 7.4 to 9.1%. There was a significant correlation between parent (r = 0.20) and adolescent (r = 0.21) reports of their perceived ideal HbA1c and their actual HbA1c result (p < 0.001), and a stronger association between parents' (r = 0.39) and adolescents' (r = 0.4) reports of the HbA1c they would be happy with and their actual HbA1c result. There were significant differences between centres on parent and adolescent reports of ideal and happy with HbA1c (8.1 < F > 17.4;p < 0.001). A lower target HbA1c and greater consistency between members of teams within centres were associated with lower centre HbA1c (F = 16.0; df = 15; p < 0.001).Conclusions: Clear and consistent setting of glycaemic targets by diabetes teams is strongly associated with HbA1c outcome in adolescents. Target setting appears to play a significant role in explaining the differences in metabolic outcomes between centres. © 2009 John Wiley & Sons A/S. [less ▲]

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See detailTarget Tracking Optimization of UAV Swarms Based on Dual-Pheromone Clustering
Brust, Matthias R. UL; Zurad, Maciej UL; Hentges, Laurent Philippe UL et al

in CYBCONF 2017-12-13 09:39:53 +0000 2017-12-13 09:39:53 +0000 (2017)

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See detailTargeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.
Kimura, Tomomi E.; Jin, Jiawei; Zi, Min et al

in Circulation Research (2010), 106(5), 961-70

RATIONALE: Mitogen-activated protein kinase (MAPK) pathways provide a critical connection between extrinsic and intrinsic signals to cardiac hypertrophy. Extracellular signal-regulated protein kinase (ERK ... [more ▼]

RATIONALE: Mitogen-activated protein kinase (MAPK) pathways provide a critical connection between extrinsic and intrinsic signals to cardiac hypertrophy. Extracellular signal-regulated protein kinase (ERK)5, an atypical MAPK is activated in the heart by pressure overload. However, the role of ERK5 plays in regulating hypertrophic growth and hypertrophy-induced apoptosis is not completely understood. OBJECTIVE: Herein, we investigate the in vivo role and signaling mechanism whereby ERK5 regulates cardiac hypertrophy and hypertrophy-induced apoptosis. METHODS AND RESULTS: We generated and examined the phenotypes of mice with cardiomyocyte-specific deletion of the erk5 gene (ERK5(cko)). In response to hypertrophic stress, ERK5(cko) mice developed less hypertrophic growth and fibrosis than controls. However, increased apoptosis together with upregulated expression levels of p53 and Bad were observed in the mutant hearts. Consistently, we found that silencing ERK5 expression or specific inhibition of its kinase activity using BIX02189 in neonatal rat cardiomyocytes (NRCMs) reduced myocyte enhancer factor (MEF)2 transcriptional activity and blunted hypertrophic responses. Furthermore, the inhibition of MEF2 activity in NRCMs using a non-DNA binding mutant form of MEF2 was found to attenuate the ERK5-regulated hypertrophic response. CONCLUSIONS: These results reveal an important function of ERK5 in cardiac hypertrophic remodeling and cardiomyocyte survival. The role of ERK5 in hypertrophic remodeling is likely to be mediated via the regulation of MEF2 activity. [less ▲]

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