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The method is motivated by the cracking-particle method (Rabczuk T., Belytschko T., International Journal ... [more ▼]A new robust and efficient approach for modeling discrete cracks in meshfree methods is described. The method is motivated by the cracking-particle method (Rabczuk T., Belytschko T., International Journal for Numerical Methods in Engineering, 2004) where the crack is modeled by a set of cracked segments. However, in contrast to the above mentioned paper, we do not introduce additional unknowns in the variational formulation to capture the displacement discontinuity. Instead, the crack is modeled by splitting particles located on opposite sides of the associated crack segments and we make use of the visibility method in order to describe the crack kinematics. We apply this method to several two- and three-dimensional problems in statics and dynamics and show through several numerical examples that the method does not show any "mesh" orientation bias. © 2010 Elsevier B.V. [less ▲]Detailed reference viewed: 134 (0 UL) Simple ClinVar:an interactive web server to explore and retrieve gene and disease variants 1 aggregated in ClinVar databasePérez-Palma, Eduardo; Gramm, Marie; Nürnberg, Peter et alin Nucleic Acids Research (2019)Clinical genetic testing has exponentially expanded in recent years, leading to an overwhelming amount of patient variants with high variability in pathogenicity and heterogeneous phenotypes. A large part ... [more ▼]Clinical genetic testing has exponentially expanded in recent years, leading to an overwhelming amount of patient variants with high variability in pathogenicity and heterogeneous phenotypes. A large part of the variant level data are comprehensively aggregated in public databases such as ClinVar. However, the ability to explore this rich resource and answer general questions such as “How many genes inside ClinVar are associated with a specific disease? or “In which part of the protein are patient variants located?” is limited and requires advanced bioinformatics processing. Here, we present Simple ClinVar (http://simple-clinvar.broadinstitute.org/) a web- server application that is able to provide variant, gene, and disease level summary statistics based on the entire ClinVar database in a dynamic and user-friendly web-interface. Overall, our web application is able to interactively answer basic questions regarding genetic variation and its known relationships to disease. By typing a disease term of interest, t he user can identify in seconds the genes and phenotypes most frequently reported to ClinVar. Subsets of variants can then be further explored, filtered, or mapped and visualized in the corresponding protein sequences. Our website will follow ClinVar monthly releases and provide easy access to rich ClinVar resources to a broader audience including basic and clinical scientists. [less ▲]Detailed reference viewed: 94 (2 UL) Simple Colloidal Models for Conductive CompositesSchilling, Tanja Scientific Conference (2014, April)Detailed reference viewed: 24 (0 UL) Simple Conditionals with Constrained Right WeakeningCasini, Giovanni ; Meyer, Thomas; Varzinczak, Ivanin Proceedings of the 28th International Joint Conference on Artificial Intelligence (IJCAI 2019) (2019)In this paper we introduce and investigate a very basic semantics for conditionals that can be used to define a broad class of conditional reasoning systems. We show that it encompasses the most popular ... [more ▼]In this paper we introduce and investigate a very basic semantics for conditionals that can be used to define a broad class of conditional reasoning systems. We show that it encompasses the most popular kinds of conditional reasoning developed in logic-based KR. It turns out that the semantics we propose is appropriate for a structural analysis of those conditionals that do not satisfy the property of Right Weakening. We show that it can be used for the further development of an analysis of the notion of relevance in conditional reasoning. [less ▲]Detailed reference viewed: 67 (5 UL) A simple consistent test of conditional symmetry in symmetrically trimmed tobit modelsChen, Tao; Tripathi, Gautam in Journal of Econometrics (2017), 198Detailed reference viewed: 201 (31 UL) A Simple Engineering Soil Surface Vibration Prediction MethodMacijauskas, Darius ; Van Baars, Stefan in Civil Engineering Research Journal (2018), 4(2), In urban areas where the infrastructure is dense and construction of new structures is near existing and sensitive buildings, frequently vibrations, caused by human activities, occur. Generated waves in ... [more ▼]In urban areas where the infrastructure is dense and construction of new structures is near existing and sensitive buildings, frequently vibrations, caused by human activities, occur. Generated waves in the soil may adversely affect surrounding buildings. These vibrations have to be predicted a priori by using currently available knowledge of the soil dynamics. In order to make a good prediction of the soil surface vibration, it is necessary to perform calculations with a Finite Element Method (FEM). The disadvantages of the FEM are that this requires a special software package and a long time for the modelling and calculations. Therefore, it would be very useful to derive a simple model for engineering purposes, which could be used to predict geotechnical vibrations close to the source, without the need of special software and long calculations. Such a method is proposed in this article. This method is validated by a vibration test performed on a peaty site in the Netherlands. The predictions made with this method, have been compared with both the field measurements and the FEM calculations. The comparison proves that by using the presented vibration prediction method, the vibrations can be predicted as accurate as with the FEM. [less ▲]Detailed reference viewed: 123 (4 UL) A simple error estimator for extended finite elementsBordas, Stéphane ; Duflot, Marc; Le, Phongin Communications in Numerical Methods in Engineering (2008), 24(11), 961-971This short communication presents the idea of an a posteriori error estimate for enriched (extended) finite elements (XFEM). The enhanced strain field against which the XFEM strains are compared, is ... [more ▼]This short communication presents the idea of an a posteriori error estimate for enriched (extended) finite elements (XFEM). The enhanced strain field against which the XFEM strains are compared, is computed through extended moving least-squares smoothing constructed using the diffraction method to preserve the discontinuity. The error estimator is the L2 norm of the difference of the XFEM strain with the enhanced strain. We prove the concept of the proposed method on a 1D example with a singular solution and a 2D fracture mechanics example and conclude with some future work based on our paradigm. [less ▲]Detailed reference viewed: 87 (1 UL) A simple mass-action model for the eukaryotic heat shock response and its mathematical validationPetre, Ion; Mizera, Andrzej ; Hyder, Claire L. et alin Natural Computing (2011), 10(1), 595-612Detailed reference viewed: 92 (0 UL) A simple method for a specific retrograde labelling of dorsal root and sympathetic ganglion cells innervating the knee joint of the cat.Hanesch, Ulrike ; Heppelmann, Berndin Journal of Neuroscience Methods (1995), 63Detailed reference viewed: 54 (0 UL) Simple monoclinic crystal phase in suspensions of hard ellipsoidsPfleiderer, P.; Schilling, Tanja in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2007), 75(2), Detailed reference viewed: 92 (2 UL) Simple Realization of a Monolithic Integrated Photoreceiver for 10GBit/s Using an InP/InGaAs HeterostructureHorstmann, M.; Hollfelder, M.; Schimpf, K. et alin Proceedings of the 8th International Conference on InP and Related Compounds, Schwäbisch Gmünd, Germany (1996)Detailed reference viewed: 63 (2 UL) The Simple Shear and Simple Tension Problems in Linear and Nonlinear ElasticityLee, Chang-Kye; Bordas, Stéphane Report (2012)Detailed reference viewed: 143 (9 UL) A simple theory for the study of SDEs driven by a fractional Brownian motion, in dimension oneNourdin, Ivan in Lecture notes in Mathematics (2008)Detailed reference viewed: 94 (1 UL) "The Simplest Protocol for Oblivious Transfer'' RevisitedGenç, Ziya Alper ; Iovino, Vincenzo; Rial, Alfredo in Information Processing Letters (2020)In 2015, Chou and Orlandi presented an oblivious transfer protocol that already drew a lot of attention both from theorists and practitioners due to its extreme simplicity and high efficiency. Chou and ... [more ▼]In 2015, Chou and Orlandi presented an oblivious transfer protocol that already drew a lot of attention both from theorists and practitioners due to its extreme simplicity and high efficiency. Chou and Orlandi claimed that their protocol is universally composable secure (UC-secure) in the random oracle model under dynamic corruptions. UC-security is a very strong security guarantee that assures that, not only the protocol in itself is secure, but can be also used safely in larger protocols. Unfortunately, in this work we point out a flaw in their security proof for the case of a corrupt sender. In more detail, we define a decisional problem and we prove that, if a correct security proof for the Chou and Orlandi's protocol is provided, then this problem can be solved correctly with overwhelming probability. Therefore, the protocol of Chou and Orlandi cannot be instantiated securely with groups for which our decisional problem cannot be solved correctly with overwhelming probability. Consequently, the protocol of Chou and Orlandi cannot be instantiated with {\em all} groups $\G$ in which the CDH problem is intractable, but only with groups in which both the CDH problem is intractable and our decisional problem can be solved with overwhelming probability. After the appearance of our work, Chou and Orlandi acknowledged the problems we pointed out in their security proof and subsequent works showed additional issues, removing the claims of UC security of their protocol. [less ▲]Detailed reference viewed: 71 (2 UL) Simplicial localization of homotopy algebras over a propYalin, Sinan in Mathematical Proceedings of the Cambridge Philosophical Society (2014), 157(3), 457468We prove that a weak equivalence between two cofibrant (colored) props in chain complexes induces a Dwyer-Kan equivalence between the simplicial localizations of the associated categories of algebras ... [more ▼]We prove that a weak equivalence between two cofibrant (colored) props in chain complexes induces a Dwyer-Kan equivalence between the simplicial localizations of the associated categories of algebras. This homotopy invariance under base change implies that the homotopy category of homotopy algebras over a prop P does not depend on the choice of a cofibrant resolution of P, and gives thus a coherence to the notion of algebra up to homotopy in this setting. The result is established more generally for algebras in combinatorial monoidal dg categories. [less ▲]Detailed reference viewed: 21 (0 UL) A simplified and accelerated phase field method for crack nucleation and propagation in highly heterogeneous materialsNguyen, Thanh Tung ; Yvonnet, Julien; Zhu, Q.-Z. et alin 20th European Conference on Fracture (2014)Detailed reference viewed: 19 (0 UL) A Simplified Approach to Computing Efficiency Bounds in Semiparametric ModelsSeverini, Thomas A.; Tripathi, Gautam in Journal of Econometrics (2001), 102Detailed reference viewed: 126 (1 UL) Simplified density indexes of walls and tie-columns for confined masonry buildings in seismic zonesCai, Gaochuang ; Su, Q.W; Tsavdaridis, K.D. et alin Journal of Earthquake Engineering (2017)This paper discusses and quantifies the minimum requirements of walls and tie-columns in confined masonry (CM) buildings located in earthquake-prone regions. A research database including 238 damaged CM ... [more ▼]This paper discusses and quantifies the minimum requirements of walls and tie-columns in confined masonry (CM) buildings located in earthquake-prone regions. A research database including 238 damaged CM buildings obtained from the 2008 Wenchuan earthquake survey is established and comprehensively examined. The requirements of masonry walls in CM buildings are discussed, and a simplified tie-column density index is proposed for evaluating the potential damage of the structures. Besides, the minimum requirements of reinforced concrete tie-columns and their maximum allowable spacing in CM buildings at different seismic intensity zones are discussed. [less ▲]Detailed reference viewed: 64 (1 UL) Simplified formation process for Cu2ZnSnS4-based solar cellsBerg, Dominik ; Crossay, Alexandre ; Guillot, Jérôme et alin Thin Solid Films (2014), 573Detailed reference viewed: 245 (1 UL) Simplified Reducibility Proofs of Church-Rosser for beta- and beta-eta-reductionKamareddine, Fairouz; Rahli, Vincent in Electronic Notes in Theoretical Computer Science (2009), 247Detailed reference viewed: 47 (3 UL)