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See detailL'abbaye Neumunster - et tout un ancien quartier urbain
Pauly, Michel UL

in Abbaye de Neumunster (2004)

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See detailThe abbot and the Monastic Community in the Gaelic Churches, 550 to 800
Pettiau, Hérold UL

in Glyn S. Burgess; Strijbosch, Clara (Eds.) The Brendan Legend. Texts and Versions (2006)

This chapters deals with aspects of the organisation of monastic communities in the Gaelic Churches from 550 to 800. It focusses on the role of the head of the community, the abbot, regarding general ... [more ▼]

This chapters deals with aspects of the organisation of monastic communities in the Gaelic Churches from 550 to 800. It focusses on the role of the head of the community, the abbot, regarding general questions of monastic discipline, organising of the liturgical life of the community, regulation of the diet and of the food provision in the community. [less ▲]

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See detailABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels
Zwarts, K. Y.; Clee, S. M.; Zwinderman, A. H. et al

in Clinical Genetics (2002), 61(2), 115-125

The authors have previously shown that individuals heterozygous for ABCA1 mutations have decreased high density lipoprotein cholesterol, increased triglycerides and an increased frequency of coronary ... [more ▼]

The authors have previously shown that individuals heterozygous for ABCA1 mutations have decreased high density lipoprotein cholesterol, increased triglycerides and an increased frequency of coronary artery disease (CAD), and that single nucleotide polymorphisms (SNPs) in the coding region of the ABCA1 gene significantly impact plasma lipid levels and the severity of CAD in the general population. They have now identified several SNPs in non-coding regions of ABCA1 which may be important for the appropriate regulation of ABCA1 expression (i.e. in the promoter, intron 1 and the 5′ untranslated region), and have examined the phenotypic effects of these SNPs in the REGRESS population. Out of 12 SNPs, four were associated with a clinical outcome. A threefold increase in coronary events with an increased family history of CAD was evident for the G-191C variant. Similarly, the C69T SNP was associated with a twofold increase in events. In contrast, the C-17G was associated with a decrease in coronary events and the InsG319 was associated with less atherosclerosis. For all these SNPs, the changes in atherosclerosis and CAD occurred without detectable changes in plasma lipid levels. These data suggest that common variation in non-coding regions of ABCA1 may significantly alter the severity of atherosclerosis, without necessarily influencing plasma lipid levels. [less ▲]

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See detailThe ABCD of cyclic quadrilaterals
Begalla, Engjell UL; Perucca, Antonella UL

Article for general public (in press)

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See detailABCDE Tutorial LuxLogAI 2018 - Default entailment course
Weydert, Emil UL

Scientific Conference (2018)

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See detailAbdications of Sovereignty in State Action and Horizontal Effect Jurisprudence
Van Der Walt, Johan Willem Gous UL

in Kahana, Tsvi; Scolnicov, Anat (Eds.) Boundaries of State, Boundaries of Rights: Human Rights, Private Actors, and Positive Obligations (2016)

This article argues that different regimes of horizontal effect adjudication invariably turn on different attitudes to state sovereignty. Aversions to horizontal effect are usually a reflection of an ... [more ▼]

This article argues that different regimes of horizontal effect adjudication invariably turn on different attitudes to state sovereignty. Aversions to horizontal effect are usually a reflection of an apprehension regarding state sovereignty (understood as a threat to liberty) whereas endorsements of horizonal effect usually reflect a positive regard for state sovereingty (as a condition for liberty). [less ▲]

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See detailAbel-Preis an Mathematiker Lennart Carleson
Molitor-Braun, Carine UL; Mortini, Raymond

Article for general public (2006)

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See detailAbel-Preis für Mathematiker Mischa Gromov
Mortini, Raymond; Schlichenmaier, Martin UL

Article for general public (2009)

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See detailAbelian varieties over finitely generated fields and the conjecture of Geyer and Jarden on torsion
Arias De Reyna Dominguez, Sara UL; Gajda, Wojciech; Petersen, Sebastian

in Mathematische Nachrichten (2013), 286(13), 1269-1286

In this paper we prove the Geyer-Jarden conjecture on the torsion part of the Mordell-Weil group for a large class of abelian varieties defined over finitely generated fields of arbitrary characteristic ... [more ▼]

In this paper we prove the Geyer-Jarden conjecture on the torsion part of the Mordell-Weil group for a large class of abelian varieties defined over finitely generated fields of arbitrary characteristic. The class consists of all abelian varieties with big monodromy, i.e., such that the image of Galois representation on l-torsion points, for almost all primes l, contains the full symplectic group. [less ▲]

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See detailAbelian varieties over number fields, tame ramification and big Galois image
Arias De Reyna Dominguez, Sara UL; Kappen, Christian

in Mathematical Research Letters (2013), 20(01), 1-17

Given a natural number n ≥ 1 and a number field K, we show the existence of an integer l_0 such that for any prime number l ≥ l_0 , there exists a finite extension F/K, unramified in all places above l ... [more ▼]

Given a natural number n ≥ 1 and a number field K, we show the existence of an integer l_0 such that for any prime number l ≥ l_0 , there exists a finite extension F/K, unramified in all places above l, together with a principally polarized abelian variety A of dimension n over F such that the resulting l-torsion representation ρ_{A,l} : G_F → GSp(A[l]) is surjective and everywhere tamely ramified. In particular, we realize GSp_{2n}(F_l) as the Galois group of a finite tame extension of number fields F' /F such that F is unramified above l. [less ▲]

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See detailAbelian varieties with tame and surjective Galois representations
Arias De Reyna Dominguez, Sara UL

Scientific Conference (2013, August)

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See detailAberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-kappaB signaling.
Hahn, M.; Burckert, J.-P.; Luttenberger, C. A. et al

in Leukemia (2017), 32(1), 72-82

The pathogenesis of chronic lymphocytic leukemia (CLL) has been linked to constitutive NF-kappaB activation but the underlying mechanisms are poorly understood. Here we show that alternative splicing of ... [more ▼]

The pathogenesis of chronic lymphocytic leukemia (CLL) has been linked to constitutive NF-kappaB activation but the underlying mechanisms are poorly understood. Here we show that alternative splicing of the negative regulator of NF-kappaB and tumor suppressor gene CYLD regulates the pool of CD5(+) B cells through sustained canonical NF-kappaB signaling. Reinforced canonical NF-kappaB activity leads to the development of B1 cell-associated tumor formation in aging mice by promoting survival and proliferation of CD5(+) B cells, highly reminiscent of human B-CLL. We show that a substantial number of CLL patient samples express sCYLD, strongly implicating a role for it in human B-CLL. We propose that our new CLL-like mouse model represents an appropriate tool for studying ubiquitination-driven canonical NF-kappaB activation in CLL. Thus, inhibition of alternative splicing of this negative regulator is essential for preventing NF-kappaB-driven clonal CD5(+) B-cell expansion and ultimately CLL-like disease. [less ▲]

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See detailThe ability to read numbers: A universal measure?
Tymms, Peter; Aleksic, Gabrijela UL; Bartholo, Tiago et al

in AERA (2018)

This study tests the hypothesis that there is a single pathway for the order in which children learn to identify numbers. Although a prime facie case can be made, systematic variation might be expected ... [more ▼]

This study tests the hypothesis that there is a single pathway for the order in which children learn to identify numbers. Although a prime facie case can be made, systematic variation might be expected because of teaching, or language of instruction, or country of origin. This study concludes that such variations are minor and that the pathway that children follow when learning to identify numbers follows the same pattern across different groups. This finding is significant in furthering our knowledge of children’s early mathematics development; it suggests that there is a universal developmental scale from which the diverse aspects of mathematical development can be viewed. This lays the foundation for international comparisons of the mathematical development of young children. [less ▲]

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See detailAblenkung. Kafkas Idee des literarischen Suizids
Mein, Georg UL

in Zeitschrift für Deutsche Philologie (2003), (2), 266-286

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See detailL'abolition de l'esclavage fête ses 130 ans au Brésil...
Santana, Dominique UL

Article for general public (2018)

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See detailAbolition de l’exequatur et présomption de compatibilité avec les droits fondamentaux
Cuniberti, Gilles UL

in Revue Critique de Droit International Privé (2014)

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See detailAbolition of Exequatur - Addressing the Commission's Concerns
Cuniberti, Gilles UL; Rueda, Isabelle UL

in Rabelszeitschrift für ausländisches und internationales Privatrecht (2011)

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See detailAbolition of peroxiredoxin-5 mitochondrial targeting during canid evolution.
Van der Eecken, Valerie; Clippe, Andre; Dekoninck, Sophie et al

in PloS one (2013), 8(9), 72844

In human, the subcellular targeting of peroxiredoxin-5 (PRDX5), a thioredoxin peroxidase, is dependent on the use of multiple alternative transcription start sites and two alternative in-frame translation ... [more ▼]

In human, the subcellular targeting of peroxiredoxin-5 (PRDX5), a thioredoxin peroxidase, is dependent on the use of multiple alternative transcription start sites and two alternative in-frame translation initiation sites, which determine whether or not the region encoding a mitochondrial targeting sequence (MTS) is translated. In the present study, the abolition of PRDX5 mitochondrial targeting in dog is highlighted and the molecular mechanism underlying the loss of mitochondrial PRDX5 during evolution is examined. Here, we show that the absence of mitochondrial PRDX5 is generalized among the extant canids and that the first events leading to PRDX5 MTS abolition in canids involve a mutation in the more 5' translation initiation codon as well as the appearance of a STOP codon. Furthermore, we found that PRDX5 MTS functionality is maintained in giant panda and northern elephant seal, which are phylogenetically closely related to canids. Also, the functional consequences of the restoration of mitochondrial PRDX5 in dog Madin-Darby canine kidney (MDCK) cells were investigated. The restoration of PRDX5 mitochondrial targeting in MDCK cells, instead of protecting, provokes deleterious effects following peroxide exposure independently of its peroxidase activity, indicating that mitochondrial PRDX5 gains cytotoxic properties under acute oxidative stress in MDCK cells. Altogether our results show that, although mitochondrial PRDX5 cytoprotective function against oxidative stress has been clearly demonstrated in human and rodents, PRDX5 targeting to mitochondria has been evolutionary lost in canids. Moreover, restoration of mitochondrial PRDX5 in dog MDCK cells, instead of conferring protection against peroxide exposure, makes them more vulnerable. [less ▲]

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See detailAbortion in the Third Reich: Ideology and the Penal System Concerning Women in the Penal Institution in Saarbrücken, Germany
Wingerter, Elisabeth UL

Presentation (2015, March 21)

With the help of almost 200 dossiers of the Penal Institution in Saarbrücken (Germany) from the period from 1928 to 1944, I examine the situation of imprisoned German women during the Nazi Regime. I am ... [more ▼]

With the help of almost 200 dossiers of the Penal Institution in Saarbrücken (Germany) from the period from 1928 to 1944, I examine the situation of imprisoned German women during the Nazi Regime. I am focusing on the cases of illegal abortions by examining individual cases as well as common ideological and legal conceptions. The dossiers helped me to make conclusions about the gap between ideological ideas concerning the German woman and the complex and dark reality of life conditions for women. Insufficient medical and sexual education along with a legal inferiority shaped the „abortion epidemics“ among lower class women. Secondary and primary sources show that along with the gradual descent of the whole legal system into a system of institutionalized crime, economic conditions also influenced the catastrophic conditions for the pregnant lower class woman. The complexity of the cases is striking: Along with the lack of understanding for the female body, economic misery, legal problems and war, many other factors appear during the research. Pressure from the own family, social norms and Christian morals played a role. Furthermore, men were an essential part of this history as husbands, fathers or rapists. Moreover, abortions developed into a business, as groups of men and women started to help other undergo abortion for money. I also explain the most common procedure of abortion and its risks. [less ▲]

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