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See detail"Neither good, nor bad, nor neutral": The Historical Dispositif of Communication Technologies
Fickers, Andreas UL

in Schreiber, Martin; Zimmermann, Clemens (Eds.) Journalism and Technological Change. Historical Perspectives, Contemporary Trends (2014)

Detailed reference viewed: 345 (17 UL)
See detailNekrologie ob een Traditiounsveräin. D’Eintracht im Thale vun Hesper seet äddi
Sagrillo, Damien UL; Schiltz, Jos

Article for general public (2012)

Detailed reference viewed: 44 (0 UL)
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See detailNematic-smectic transition under confinement in liquid crystalline colloidal shells
Liang, Hsin-Ling; Schymura, Stefan; Rudquist, Per et al

in Physical Review Letters (2011), 106(24), 247801

We carry out the first study of smectic liquid crystalline colloidal shells and investigate how their complex internal structure depends on the director configuration in the nematic phase, preceding the ... [more ▼]

We carry out the first study of smectic liquid crystalline colloidal shells and investigate how their complex internal structure depends on the director configuration in the nematic phase, preceding the smectic phase on cooling. Differences in the free energy cost of director bend and splay give an initial skewed distribution of topological defects in the nematic phase. In the smectic phase, the topological and geometrical constraints of the spherical shell imposed on the developing 1D quasi-long-range order create a conflict that triggers a series of buckling instabilities. Two different characteristic defect patterns arise, one driven by the curvature of the shell, the other by the strong nonuniformities in the director field in the vicinity of the topological defects. [less ▲]

Detailed reference viewed: 190 (1 UL)
See detailNemzetközi Bűnügyi Együttműködés az Európai Unióban
Ligeti, Katalin UL

Book published by MTA JTI (2002)

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See detailNeo-Institutionalismus
Powell, Justin J W UL

in Hedderich, Ingeborg; Biewer, Gottfried; Hollenweger, Judith (Eds.) et al Handbuch Inklusion und Sonderpädagogik (2016)

Insbesondere mit Hilfe des Neo-Institutionalismus kann aufgezeigt werden, dass sonderpädagogische Förderung wie auch schulische Inklusion als Prinzipien weltweit diffundieren und zu globalen Normen ... [more ▼]

Insbesondere mit Hilfe des Neo-Institutionalismus kann aufgezeigt werden, dass sonderpädagogische Förderung wie auch schulische Inklusion als Prinzipien weltweit diffundieren und zu globalen Normen geworden sind. Andererseits können Barrieren der schulischen Inklusion darauf zurückgeführt werden, dass sonderpädagogische Fördersysteme in vielen Ländern vornehmlich als segregierende oder separierende Organisationsformen institutionalisiert wurden, die schwer zu verändern sind. Neo-Institutionalismus schärft den Blick auf die Institutionalisierung bestimmter Organisationsformen und Organisationen, deren Angleichung und deren Persistenz. [less ▲]

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See detailUn néo-mercantilisme allemand? Hjalmar Schacht et la politique économique, monétaire et financière du IIIe Reich
Clavert, Frédéric UL

in Alcouffe, Alain; Diebold, Claude (Eds.) Histoire de la pensée économique allemande (2008)

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See detailNeoclassical growth and the "trivial" steady state
Hakenes, Hendrik; Irmen, Andreas UL

in Journal of Macroeconomics (2008), 30(3), 1097-1103

According to a common perception, the neoclassical economy void of capital cannot evolve to strictly positive levels of output, if capital is essential. We challenge this view and claim for a broad class ... [more ▼]

According to a common perception, the neoclassical economy void of capital cannot evolve to strictly positive levels of output, if capital is essential. We challenge this view and claim for a broad class of production functions, encompassing the neoclassical production function, that a take-off is possible even though the initial capital stock is zero and capital is essential. Since the marginal product of capital is initially infinite, the \"trivial\" steady state becomes so unstable that the solution to the equation of motion involves the possibility of a take-off. When it happens, the take-off has no cause. [less ▲]

Detailed reference viewed: 117 (2 UL)
See detailNeoclassical Growth and the 'Trivial' Steady State
Hakenes, Hendrik; Irmen, Andreas UL

Report (2005)

If capital is an essential input, the neoclassical growth model has a steady state with zero capital. From this, one is inclined to conclude that an economy starting without capital can never grow. We ... [more ▼]

If capital is an essential input, the neoclassical growth model has a steady state with zero capital. From this, one is inclined to conclude that an economy starting without capital can never grow. We challenge this view and claim that, if the production function satisfies the Inada conditions, a take-off is possible even though the initial capital stock is zero and capital is essential. Since the marginal product of capital is initially infinite, the ‘trivial’ steady state becomes so unstable that the solution to the equation of motion involves the possibility of a take-off, even without capital. When it happens, the take-off is spontaneous; there is no causality. [less ▲]

Detailed reference viewed: 134 (3 UL)
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See detailNeonatal maternal separation stress alters neuropathic pain behaviour and spinal nociceptive processing in rats
Genty, Julien UL; Le Coz, Glenn-Marie UL; Anton, Fernand UL et al

Scientific Conference (2014)

Aims Early life stress enhances vulnerability to metabolic and mental disorders in adulthood. Altered pain sensitivity and dysfunctional emotional processing have been described in this context. We ... [more ▼]

Aims Early life stress enhances vulnerability to metabolic and mental disorders in adulthood. Altered pain sensitivity and dysfunctional emotional processing have been described in this context. We assessed the impact of neonatal maternal separation (MS) on chronic constriction injury (CCI) induced neuropathic pain behavior and biochemical spinal processing in early adulthood. Methods Four groups of rats were tested: Controls, MS, CCI, MS+CCI. For MS, pups were separated from the dam from postnatal day 2 to 12 for 3 hours per day. At an age of 7 weeks mechanical and thermal pain thresholds where assessed by the von Frey and the cold plate test. CCI surgery was performed in two of the experimental groups and behavioural measurements were continued until day 21 post surgery. After decapitation spinal cord levels L4/L5 were removed and total RNA was extracted to perform qPCR. Results MS alone did not affect pain thresholds. Surprisingly, MS+CCI rats were less sensitive to mechanical and thermal stimuli compared to CCI. Regarding the biochemical data, MS as well as MS+CCI led to an upregulation of glial markers, cytokines and growth factors and to a downregulation of glutamate receptors and transporters. Conclusion Behavioral and biochemical data are conflicting. The reduced pain sensitivity in MS animals is in contrast to activation of glia and enhanced expression of cytokines but in line with reduced glutamatergic signalling. Since MS and MS+CCI groups did not differ, pain-related processing may have been outweighed by stress-related programming of biochemical reactivity. [less ▲]

Detailed reference viewed: 125 (14 UL)
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See detailNero? Wer war denn Nero? Eine Besprechung der drei Ausstellungen in Trier
Jungblut, Marie-Paule UL

in Museum Aktuell (2016), 233

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See detailNested Graphs: a model to efficiently distribute multi-agent systems on HPC clusters
Rousset, Alban UL; Herrmann, Bénédicte; Lang, Christophe et al

in Concurrency & Computation : Practice & Experience (2017), 30(7), 22

Computational simulation is becoming increasingly important in numerous research fields. Depending on the modeled system, several methods such as differential equations or Monte-Carlo simulations may be ... [more ▼]

Computational simulation is becoming increasingly important in numerous research fields. Depending on the modeled system, several methods such as differential equations or Monte-Carlo simulations may be used to represent the system behavior. The amount of computation and memory needed to run a simulation depends on its size and precision and large simulations usually lead to long runs thus requiring to adapt the model to a parallel system. Complex systems are often simulated using Multi-agent systems (MAS). While linear system based models benefit from a large set of tools to take advantage of parallel resources, multi-agent systems suffer from a lack of platforms that ease the use of such resources. In this paper, we propose the use of Nested Graphs for a new modeling approach that allows the design of large, complex and multi-scale multi-agent models which can efficiently be distributed on parallel resources. Nested Graphs are formally defined and are illustrated on the well-known predator-prey model. We also introduce PDMAS (Parallel and Distributed Multi-Agent System) a platform that implements the Nested Graph modeling approach to ease the distribution of multi-agent models on High Performance Computing clusters. Performance results are presented to validate the efficiency of the resulting models. [less ▲]

Detailed reference viewed: 61 (2 UL)
See detail"Nët e weidert Rad, mee de Sandkär, deen alles a Fro stellt" : 50 Joër Generalstreik
Scuto, Denis UL

Article for general public (1992)

Detailed reference viewed: 37 (0 UL)
See detailThe Netherlands: Policy-enhanced Inequalities Tempered by Household Formation
Haas, Christina UL; Salverda, Wiemer; De Graaf-Zijl, Marloes et al

in Nolan, Brian; Salverda, Wiemer; Checchi, Daniele (Eds.) et al Changing Inequalities & Societal Impacts in Rich Countries. Thirty Countries' Experiences (2014)

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See detailNetPower DemoLab A Test Bed Infrastructure for Security and Reliability Investigations of SCADA Systems
Jostock, Markus UL; Sachau, Jürgen UL

in Abstract paper of 2011 Grande Region Security and Reliability Day (2011)

The purpose of this paper is to present the capabilities of the new NetPower DemoLab of the Interdisciplinary Centre for Reliability and Trust at the University of Luxembourg, operated by the Systems and ... [more ▼]

The purpose of this paper is to present the capabilities of the new NetPower DemoLab of the Interdisciplinary Centre for Reliability and Trust at the University of Luxembourg, operated by the Systems and Control group, and to stimulate potential public or private collaborations in the area of SCADA security and reliability investigations. [less ▲]

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See detailNetwork Analysis and Routing eVALuation V3.0
Melakessou, Foued UL; Engel, Thomas UL

Scientific Conference (2014, May 15)

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See detailNetwork analysis for systems biology
Chaiboonchoe, A.; Jurkowski, Wiktor UL; Pellet, J. et al

in Prokop, Aleš; Csukás (Eds.) Springer book in Systems Biology, Vol.1: Systems Biology:, Integrative Biology and Simulation Tools (2013)

Network analysis is an essential component of systems biology approaches toward understanding the molecular and cellular interactions underlying biological systems functionalities and their perturbations ... [more ▼]

Network analysis is an essential component of systems biology approaches toward understanding the molecular and cellular interactions underlying biological systems functionalities and their perturbations in disease. Regulatory and signalling pathways, which involve DNA, RNA proteins and metabolites as key elements, coordinate most aspects of cellular functioning. Cellular processes, which are dependent on the structure and dynamics of gene regulatory networks, can be studied by employing a network representation of molecular interactions. In this chapter we describe several types of networks and how combination of different analytic approaches can be used to study diseases. We provide a list of selected tools for visualization and network analysis. We introduce protein-protein interaction networks, gene regulatory networks, signalling networks and metabolic networks. We then define concepts underlying network representation of cellular processes and molecular interactions. We finally discuss how the level of accuracy in inferring functional relationships influences the choice of methods applied for the analysis of a particular network type. [less ▲]

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See detailNetwork analysis of neurodegenerative disease highlights a role of toll-like receptor signaling
Nguyen, Thanh-Phuong UL; Caberlotto, Laura; Morine, Melissa J. et al

in BioMed Research International (2014), 2014

Despite significant advances in the study of the molecular mechanisms altered in the development and progression of neurodegenerative diseases (NDs), the etiology is still enigmatic and the distinctions ... [more ▼]

Despite significant advances in the study of the molecular mechanisms altered in the development and progression of neurodegenerative diseases (NDs), the etiology is still enigmatic and the distinctions between diseases are not always entirely clear. We present an efficient computationalmethod based on protein-protein interaction network (PPI) tomodel the functional network of NDs. The aim of this work is fourfold: (i) reconstruction of a PPI network relating to the NDs, (ii) construction of an association network between diseases based on proximity in the disease PPI network, (iii) quantification of disease associations, and (iv) inference of potentialmolecularmechanisminvolved in the diseases.The functional links of diseases not only showed overlap with the traditional classification in clinical settings, but also offered new insight into connections between diseases with limited clinical overlap. To gain an expanded view of the molecular mechanisms involved in NDs, both direct and indirect connector proteins were investigated. The method uncovered molecular relationships that are in common apparently distinct diseases and provided important insight into the molecular networks implicated in disease pathogenesis. In particular, the current analysis highlighted the Toll-like receptor signaling pathway as a potential candidate pathway to be targeted by therapy in neurodegeneration. [less ▲]

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See detailNetwork analysis of respiratory sensations during stress and sports using flowthrough centrality measurements
Petersen, Sibylle UL; Mann, Charles F.; Matula, David W. et al

in International Journal of Psychology (2008), 43(3-4), 329-329

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See detailNetwork analysis to model diseases and cellular reprogramming for therapeutic intervention
Crespo, Isaac UL

Doctoral thesis (2013)

Applications of network analysis to the study of disease can be divided into two main categories: disease description, including characterisation, diagnosis and prognosis; and disease treatment, including ... [more ▼]

Applications of network analysis to the study of disease can be divided into two main categories: disease description, including characterisation, diagnosis and prognosis; and disease treatment, including drug target discovery and cellular reprogramming, together with its applications to regenerative medicine. In this dissertation, I will critically discuss some research projects on which I have been working during my PhD program. In correspondence with the two aforementioned categories, these projects can be broken down into two different blocks of content, with the common goal of acquiring insights into the study of disease. In the first block of contents, corresponding with Chapter 2, I will explain and discuss novel strategies for network-based analysis and modelling which have been applied for disease description and characterisation in different case-studies, namely the metabolic syndrome, prion disease and the epithelial to mesenchymal transition in breast cancer. Indeed, these projects exploited the evolutionary conservation of motifs of regulatory interactions and consistency between computed and experimentally validated expression so as to reconstruct dynamical models and create a network-based characterisation of the corresponding systems. With regards the second block of content, corresponding with Chapter 3, I explain and discuss novel computational methods which have been developed during my PhD program to address the task of the artificial induction of cellular reprogramming; something with a wealth of potential applications when it comes to the creation of disease models and in the field of regenerative medicine. Within the general conclusion discussion focuses on the fact that, although the methodology explained in this work was developed in the context of disease study, one may find the application of some of these ideas and strategies fitting for other problems. Indeed, the same principles applied to detect driver genes capable of changing the cell phenotype when perturbed can also be applied to control biological living systems for basic research or industrial purposes. These principles could also be potentially extended to higher level systems than the cellular level (tissue or cell population level). [less ▲]

Detailed reference viewed: 188 (17 UL)