Kleines Land, große Herausforderungen: Anmerkungen zu Architektur und Urbanismus in Luxemburg

in Flagge, Ingeborg (Ed.) Witry & Witry - Über das Wohnen (2018)

Der Beitrag enthält eine Reflexion über die Praxis von Architektur, Stadtplanung und Urbanismus im Großherzogtum Luxemburg. Insofern stellt er eine Rahmung für die in dem Band präsentierte Werkschau des ... [more ▼]

Der Beitrag enthält eine Reflexion über die Praxis von Architektur, Stadtplanung und Urbanismus im Großherzogtum Luxemburg. Insofern stellt er eine Rahmung für die in dem Band präsentierte Werkschau des Büros Witry & Witry in Echternach, Luxemburg, dar. Es geht um die Spezifika der sozioökonomischen Entwicklung des Landes und ihrer Implikationen für die baulich-räumliche Entwicklung, die ohne Berücksichtigung Ersterer nicht angemessen nachzuvollziehen ist. Entsprechendes gilt für die Positionierung planerischer Interventionen, oder für die Beurteilung der Passfähigkeit von Innovationen wie Partizipation der Öffentlichkeit. [less ▲]

Kleist speichern. Zur Verzeichnung des handschriftlichen Nachlasses von Georg Minde-Pouet

in Brandenburger Kleist-Blätter (1995), 8

Die Kleist-Sammlung in der Amerika-Gedenkbibliothek, Berlin

in Beiträge zur Kleist-Forschung (1995), 9

Das Klima der Großregion SaarLorLux

E-print/Working paper (2009)

Die beiden Klimakarten der Großregion, die hier beschrieben werden, zeigen die Jahresmitteltemperaturen und das Jahresmittel der Niederschläge für den Zeitraum von 1971 bis 2000.

Klinische Psychologie: Körperliche Erkrankungen

Book published by Weinheim: Verlagsgruppe Beltz - Psychologie Verlags Union. (2009)

The book describes in uniformly structured chapters the foundations and the application of psychological assessment and treatment approaches for 8 chronic physical conditions: cardiovascular disorders ... [more ▼]

The book describes in uniformly structured chapters the foundations and the application of psychological assessment and treatment approaches for 8 chronic physical conditions: cardiovascular disorders, COPD, obesity, diabetes, cancer, HIV, musculo-skeletal disorders and chronic pain, and neurological conditions. It is unique in its practical approach by giving advice on empirically based methods from Clinical and Health Psychology. It is also rare to find a monograph on this topic, as most volumes are edited books that attempt to provide a more detailed account of current research, which is usually out-dated by the time the book is published. The current monograph draws almost exclusively on meta-analyses rather than to “get lost in detail”, thereby providing a solid and more lasting empirical foundation that is translated into recommendations for daily practice. It is also low-cost and user friendly as supporting material (e.g. assessment methods, therapeutic formulations, case histories etc.) is published as pdf via the publisher’s web-site. [less ▲]

A KLM Perspective on Defeasible Reasoning for Description Logics

in Turhan, Anni-Yasmin; Wolter, Frank; Lutz, Carsten (Eds.) et al Description Logic, Theory Combination, and All That - Essays Dedicated to Franz Baader on the Occasion of His 60th Birthday (2019)

In this paper we present an approach to defeasible reasoning for the description logic ALC. The results discussed here are based on work done by Kraus, Lehmann and Magidor (KLM) on defeasible conditionals ... [more ▼]

In this paper we present an approach to defeasible reasoning for the description logic ALC. The results discussed here are based on work done by Kraus, Lehmann and Magidor (KLM) on defeasible conditionals in the propositional case. We consider versions of a preferential semantics for two forms of defeasible subsumption, and link these semantic constructions formally to KLM-style syntactic properties via representation results. In addition to showing that the semantics is appropriate, these results pave the way for more effective decision procedures for defeasible reasoning in description logics. With the semantics of the defeasible version of ALC in place, we turn to the investigation of an appropriate form of defeasible entailment for this enriched version of ALC. This investigation includes an algorithm for the computation of a form of defeasible entailment known as rational closure in the propositional case. Importantly, the algorithm relies completely on classical entailment checks and shows that the computational complexity of reasoning over defeasible ontologies is no worse than that of the underlying classical ALC. Before concluding, we take a brief tour of some existing work on defeasible extensions of ALC that go beyond defeasible subsumption. [less ▲]

Der Klöppelkrieg 1798 im Wälderdepartement: Aufstand gegen die Modernisierung?

in Pelinka, A.; Reinalter, H. (Eds.) Die Französische Revolution und das Projekt der Moderne (2002)

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions

in Cell Reports (2017)

Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model.

in PloS one (2013), 8(12), 83714

Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of ... [more ▼]

Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of dysfunctional, unfolded proteins in aging mitochondria. Mortalin dysfunction associated with Parkinson's disease (PD) increases the vulnerability of cultured cells to proteolytic stress and leads to changes in mitochondrial function and morphology. To date, Drosophila melanogaster has been successfully used to investigate pathogenesis following the loss of several other PD-associated genes. We generated the first loss-of-Hsc70-5/mortalin-function Drosophila model. The reduction of Mortalin expression recapitulates some of the defects observed in the existing Drosophila PD-models, which include reduced ATP levels, abnormal wing posture, shortened life span, and reduced spontaneous locomotor and climbing ability. Dopaminergic neurons seem to be more sensitive to the loss of mortalin than other neuronal sub-types and non-neuronal tissues. The loss of synaptic mitochondria is an early pathological change that might cause later degenerative events. It precedes both behavioral abnormalities and structural changes at the neuromuscular junction (NMJ) of mortalin-knockdown larvae that exhibit increased mitochondrial fragmentation. Autophagy is concomitantly up-regulated, suggesting that mitochondria are degraded via mitophagy. Ex vivo data from human fibroblasts identifies increased mitophagy as an early pathological change that precedes apoptosis. Given the specificity of the observed defects, we are confident that the loss-of-mortalin model presented in this study will be useful for further dissection of the complex network of pathways that underlie the development of mitochondrial parkinsonism. [less ▲]

Know your shareholder, der intermediärsgestützte Aktionärsbegriff und das Hauptversammlungsverfahren - zur Umsetzung des Kapitels la der reformierten AktionärsrechteRL

in Zeitschrift für Unternehmens- und Gesellschaftsrecht (2019)