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See detail3D visualization of archaeological uncertainty
Sifniotis, M.; Jackson, B. J. C.; Mania, K. et al

in Proc. ACM Symposium on Applied Perception (2010)

By uncertainty, we define an archaeological expert's level of confidence in an interpretation deriving from gathered evidence. Archaeologists and computer scientists have urged caution in the use of 3D ... [more ▼]

By uncertainty, we define an archaeological expert's level of confidence in an interpretation deriving from gathered evidence. Archaeologists and computer scientists have urged caution in the use of 3D for archaeological reconstructions because the availability of other possible hypotheses is not always being acknowledged. This poster presents a 3D visualization system of archaeological uncertainty. [less ▲]

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See detail3D-Formanalyse von retroperitonealen Tumoren im Kindesalter: entwicklung einer statistischen 2D/3D-Methodik und Anwendung dieser mit MRT-Datensätzen
Giebel, Stefan Markus; Nourkami, N.; Leuschner, I. et al

Scientific Conference (2010, September 18)

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See detail3DBodyTex: Textured 3D Body Dataset
Saint, Alexandre Fabian A UL; Ahmed, Eman UL; Shabayek, Abd El Rahman UL et al

in 2018 Sixth International Conference on 3D Vision (3DV 2018) (2018)

In this paper, a dataset, named 3DBodyTex, of static 3D body scans with high-quality texture information is presented along with a fully automatic method for body model fitting to a 3D scan. 3D shape ... [more ▼]

In this paper, a dataset, named 3DBodyTex, of static 3D body scans with high-quality texture information is presented along with a fully automatic method for body model fitting to a 3D scan. 3D shape modelling is a fundamental area of computer vision that has a wide range of applications in the industry. It is becoming even more important as 3D sensing technologies are entering consumer devices such as smartphones. As the main output of these sensors is the 3D shape, many methods rely on this information alone. The 3D shape information is, however, very high dimensional and leads to models that must handle many degrees of freedom from limited information. Coupling texture and 3D shape alleviates this burden, as the texture of 3D objects is complementary to their shape. Unfortunately, high-quality texture content is lacking from commonly available datasets, and in particular in datasets of 3D body scans. The proposed 3DBodyTex dataset aims to fill this gap with hundreds of high-quality 3D body scans with high-resolution texture. Moreover, a novel fully automatic pipeline to fit a body model to a 3D scan is proposed. It includes a robust 3D landmark estimator that takes advantage of the high-resolution texture of 3DBodyTex. The pipeline is applied to the scans, and the results are reported and discussed, showcasing the diversity of the features in the dataset. [less ▲]

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See detail3‑Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L‑Serine Synthesis
Paczia, Nicole UL; Becker, Julia UL; Conrotte, Jean-François UL et al

in Biochemistry (2019)

The enzymatic mechanism of 3-phosphoglycerate to 3-phosphohydroxypyruvate oxidation, which forms the first step of the main conserved de novo serine synthesis pathway, has been revisited recently in ... [more ▼]

The enzymatic mechanism of 3-phosphoglycerate to 3-phosphohydroxypyruvate oxidation, which forms the first step of the main conserved de novo serine synthesis pathway, has been revisited recently in certain microorganisms. While this step is classically considered to be catalyzed by an NAD-dependent dehydrogenase (e.g., PHGDH in mammals), evidence has shown that in Pseudomonas, Escherichia coli, and Saccharomyces cerevisiae, the PHGDH homologues act as transhydrogenases. As such, they use α-ketoglutarate, rather than NAD+, as the final electron acceptor, thereby producing D-2-hydroxyglutarate in addition to 3-phosphohydroxypyruvate during 3-phosphoglycerate oxidation. Here, we provide a detailed biochemical and sequence−structure relationship characterization of the yeast PHGDH homologues, encoded by the paralogous SER3 and SER33 genes, in comparison to the human and other PHGDH enzymes. Using in vitro assays with purified recombinant enzymes as well as in vivo growth phenotyping and metabolome analyses of yeast strains engineered to depend on either Ser3, Ser33, or human PHGDH for serine synthesis, we confirmed that both yeast enzymes act as transhydrogenases, while the human enzyme is a dehydrogenase. In addition, we show that the yeast paralogs differ from the human enzyme in their sensitivity to inhibition by serine as well as hydrated NADH derivatives. Importantly, our in vivo data support the idea that a 3PGA transhydrogenase instead of dehydrogenase activity confers a growth advantage under conditions where the NAD+:NADH ratio is low. The results will help to elucidate why different species evolved different reaction mechanisms to carry out a widely conserved metabolic step in central carbon metabolism. [less ▲]

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See detail§ 4 WpHG zur Zuständigkeit der Bundesanstalt für Finanzdienstleistungsaufsicht, Kapitalmarktrechtskommentar
Zetzsche, Dirk Andreas UL

in Schwark, E.; Zimmer, D. (Eds.) Kapitalmarktrechtskommentar (2010)

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See detail4-Amino-1,2,4-triazole: Playing a key role in the chemical deposition of Cu–In–Ga metal layers for photovoltaic applications.
Berner, Ulrich; Widenmeyer, Markus; Engler, Patrick et al

in Thin Solid Films (2014)

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See detail4. Forschungsbericht zur Weiterentwicklung des Arbeitsqualitätsindexes in Luxemburg
Sischka, Philipp UL; Steffgen, Georges UL

E-print/Working paper (2019)

Der Survey zu dem „Quality of Work Index Luxembourg“ (QoW), der von der Universität Luxemburg und der luxemburgischen Chambré des Salariés entwickelt wurde (Steffgen, Kohl, 2013; Sischka, Steffgen, 2015 ... [more ▼]

Der Survey zu dem „Quality of Work Index Luxembourg“ (QoW), der von der Universität Luxemburg und der luxemburgischen Chambré des Salariés entwickelt wurde (Steffgen, Kohl, 2013; Sischka, Steffgen, 2015, 2016, 2017), wurde 2017 bereits zum fünften Mal mittels einer telefonischen Befragung durchgeführt. Ziel des Index ist es, die erlebte Arbeitssituation und -qualität luxemburgischer Arbeitnehmer zu erfassen. Der vorliegende Bericht dokumentiert die psychometrische Testung der Güte des aktuellen Erhebungsinstruments. Dazu erfolgt zunächst eine Beschreibung der für die Skalen genutzten Items, die Überprüfung der internen Konsistenz der jeweiligen Skala mittels verschiedener Reliabilitätsstatistiken (Cronbach’s Alpha, Korrelationsanalysen der Items) sowie Koeffizienten zur Beschreibung der Skalenverteilung. Konfirmatorische Faktorenanalysen dienen dazu, zu testen, ob die Items auf den a priori festgelegten Faktoren laden und ob sich die unterstellte Faktorenstruktur auch in den Daten zeigt. Außerdem werden die Zusammenhänge der Skalen mittels Korrelationsanalysen über-prüft. Die QoW-Skalen werden außerdem auf verschiedene Well-Being-Skalen regressiert, um deren Relevanz für den QoW-Index zu prüfen. Da der QoW Survey teilweise als Panelbefragung durchgeführt wird, wird außerdem geklärt, ob es hinsichtlich demographischer Eigenschaften der Befragten, hinsichtlich der QoW-Skalen oder hinsichtlich verschiedener Well-Being-Maße zu systematischen Ausfällen seit der letzten Welle gekommen ist. Ebenso werden einige Längsschnitt-Regressionsanalysen gerechnet, um zu überprüfen, ob einige Arbeitsbedingungen längerfristige Effekte auf das Well-Being der Arbeitnehmer aufweisen. Die QoW-Befragung 2017 hat außerdem das Schwerpunktthema „Digitalisierung“ behandelt. Die Themenblöcke werden mittels Latenter Profile-Analysen untersucht. Im Anschluss wird überprüft ob sich die extrahierten Profile hinsichtlich der QoW- und der Well-Being-Skalen unterscheiden. Abschließend wird das gesamte Erhebungsinstrument zusammenfassend diskutiert und Empfehlungen bezüglich der weiteren Entwicklung der Skalen gegeben. [less ▲]

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See detail4.2 Social Dynamics Metrics-Working Group Report
Benenson, Zinaida; Bleikertz, Sören; Foley, Simon N. et al

in Socio-Technical Security Metrics (2015)

Individuals continually interact with security mechanisms when performing tasks in everyday life. These tasks may serve personal goals or work goals, be individual or shared. These interactions can be ... [more ▼]

Individuals continually interact with security mechanisms when performing tasks in everyday life. These tasks may serve personal goals or work goals, be individual or shared. These interactions can be influenced by peers and superiors in the respective environments (workplace, home, public spaces), by personality traits of the users, as well as by contextual constraints such as available time, cognitive resources, and perceived available effort. All these influencing factors, we believe, should be considered in the design, implementation and maintenance of good socio-technical security mechanisms. Therefore, we need to observe reliable socio-technical data, and then transform them into meaningful and helpful metrics for user interactions and influencing factors. More precisely, there are three main questions that the group discussed: 1. What data do we need to observe and what of this data we actually can observe and measure? 2. How can we observe and measure? 3. What can we do with the results of the observations? [less ▲]

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See detail40 editions of ICSE: the ruby anniversary celebration
Bianculli, Domenico UL; Medvidović, Nenad; Rosenblum, David R.

Book published by self-published (2018)

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See detail40 Jahre später : Kann die Einschätzung von Grundschullehrkräften zur Intelligenz ihrer Schülerinnen und Schüler deren Bildungsrenditen als Erwachsene vorhersagen?
Brunner, M.; Fischbach, A.; Baudson, Tanja Gabriele UL et al

Scientific Conference (2015)

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See detail40 Jahre später: Kann die Einschätzung von Grundschullehrkräften zur Intelligenz ihrer Schülerinnen und Schülern deren Bildungsrenditen als Erwachsene vorhersagen?
Brunner, Martin; Fischbach, Antoine UL; Baudson, Tanja Gabriele et al

Scientific Conference (2015, March)

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See detail40 Most Expensive Photographs. Blouin Art+Auction, Databank
Kräussl, Roman UL

Diverse speeches and writings (2017)

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See detail40 Most Expensive Sculptures. Blouin Art+Auction, Databank
Kräussl, Roman UL

Diverse speeches and writings (2017)

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See detail40. Komplexe Überdachung II: Luxemburg. Die Genese einer neuen Nationalsprache
Gilles, Peter UL

in Herrgen, Joachim; Schmidt, Jürgen-Erich (Eds.) Language and Space - An International Handbook of Linguistic Variation. Vol. 4 Deutsch (in press)

Der Beitrag behandelt die komplexe Sprachensituation Luxemburgs, mit Fokus auf den germanischen Varietäten, i.e. Deutsch und Luxemburgisch, im Hinblick auf Überdachung und ihre sprachgeschichtlichen ... [more ▼]

Der Beitrag behandelt die komplexe Sprachensituation Luxemburgs, mit Fokus auf den germanischen Varietäten, i.e. Deutsch und Luxemburgisch, im Hinblick auf Überdachung und ihre sprachgeschichtlichen Verschiebungen. In dieser varietätenlinguistischen Perspektive liegt der Schwerpunkt auf der äußeren Sprachgeschichte; Aspekte der inneren Sprachgeschichte werden aus Platzgründen lediglich anhand ausgewählter Beispiele thematisiert. [less ▲]

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See detail§§ 49 - 66 KAGB zur grenzüberschreitenden Tätigkeit und zum Europäischen Pass
Zetzsche, Dirk Andreas UL; München, A.

in Kapitalanlagegesetzbuch, Kommentar (2019)

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See detail49. Thierry Revol: Représentation du sacré dans les textes dramatiques des XIe-XIIIe siècles en France
Cicotti, Claudio UL

in Zeitschrift für Romanische Philologhie (2002), 118(4), 744-745

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See detail4D Biology for health and disease
Abrahams, J. P.; Apweiler, R.; Balling, Rudi UL et al

in New Biotechnology (2011), 28(4), 291-293

The "4D Biology Workshop for Health and Disease", held on 16-17th of March 2010 in Brussels, aimed at finding the best organising principles for large-scale proteomics, interactomics and structural ... [more ▼]

The "4D Biology Workshop for Health and Disease", held on 16-17th of March 2010 in Brussels, aimed at finding the best organising principles for large-scale proteomics, interactomics and structural genomics/biology initiatives, and setting the vision for future high-throughput research and large-scale data gathering in biological and medical science. Major conclusions of the workshop include the following. (i) Development of new technologies and approaches to data analysis is crucial. Biophysical methods should be developed that span a broad range of time/spatial resolution and characterise structures and kinetics of interactions. Mathematics, physics, computational and engineering tools need to be used more in biology and new tools need to be developed. (ii) Database efforts need to focus on improved definitions of ontologies and standards so that system-scale data and associated metadata can be understood and shared efficiently. (iii) Research infrastructures should play a key role in fostering multidisciplinary research, maximising knowledge exchange between disciplines and facilitating access to diverse technologies. (iv) Understanding disease on a molecular level is crucial. System approaches may represent a new paradigm in the search for biomarkers and new targets in human disease. (v) Appropriate education and training should be provided to help efficient exchange of knowledge between theoreticians, experimental biologists and clinicians. These conclusions provide a strong basis for creating major possibilities in advancing research and clinical applications towards personalised medicine. [less ▲]

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See detail4th Conference on Poisson Geometry and related fields
Poncin, Norbert UL

Report (2004)

Speakers' abstracts and list of participants of the International Conference on 'Poisson Geometry and related fields' organized in June 2004 at the University of Luxembourg by Norbert Poncin

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See detail5 Figures de l’Histoire des idées européennes ou la recherche de la Communauté politique
Poirier, Philippe UL

in Arjakovsky, Antoine (Ed.) Histoire de la conscience européenne (2016)

Il ne s’agit pas de produire un récit exhaustif ou apologétique ou exclusif de la conscience européenne. Il s’agit de rendre visible la réalité mouvante d’une conscience européenne qui s’affirme de plus ... [more ▼]

Il ne s’agit pas de produire un récit exhaustif ou apologétique ou exclusif de la conscience européenne. Il s’agit de rendre visible la réalité mouvante d’une conscience européenne qui s’affirme de plus en plus en Europe. Pour n’avoir aucun lieu où se penser et où se refléter, celle-ci est bien souvent abandonnée à elle-même au point de douter de sa réalité propre. Mais les enjeux politiques, économiques et culturels de l’Europe politique sont tels que l’Union européenne ne pourra plus se permettre trop longtemps de se passer de récit commun. [less ▲]

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See detail5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Hopkinson, Richard J.; Tumber, Anthony; Yapp, Clarence et al

in Chemical Science (2013), 4(8), 3110-3117

2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase panel, we compare the inhibitory activities of 5-carboxy-8-hydroxyquinoline ... [more ▼]

2-Oxoglutarate and iron dependent oxygenases are therapeutic targets for human diseases. Using a representative 2OG oxygenase panel, we compare the inhibitory activities of 5-carboxy-8-hydroxyquinoline (IOX1) and 4-carboxy-8-hydroxyquinoline (4C8HQ) with that of two other commonly used 2OG oxygenase inhibitors, N-oxalylglycine (NOG) and 2,4-pyridinedicarboxylic acid (2,4-PDCA). The results reveal that IOX1 has a broad spectrum of activity, as demonstrated by the inhibition of transcription factor hydroxylases, representatives of all 2OG dependent histone demethylase subfamilies, nucleic acid demethylases and gamma-butyrobetaine hydroxylase. Cellular assays show that, unlike NOG and 2,4-PDCA, IOX1 is active against both cytosolic and nuclear 2OG oxygenases without ester derivatisation. Unexpectedly, crystallographic studies on these oxygenases demonstrate that IOX1, but not 4C8HQ, can cause translocation of the active site metal, revealing a rare example of protein ligand-induced metal movement. [less ▲]

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