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See detailEvidence for low temperature phase transition in Rb2ZnCl4 from dielectric constant and birefringence measurements
Günter, P.; Sanctuary, Roland UL; Rohner, F. et al

in Solid State Communications (1981), 37(11), 883-888

Temperature dependences of the dielectric constants [epsilon]i and of the birefringences [Delta]ni for light propagation directions along all the three crystallographic axes (i = a, b, c) have been ... [more ▼]

Temperature dependences of the dielectric constants [epsilon]i and of the birefringences [Delta]ni for light propagation directions along all the three crystallographic axes (i = a, b, c) have been measured between 5 and 350 K. The optical measurements clearly reveal a new phase transition at TL = 75 K, below which the crystal structure is transformed from the ferroelectric Pna21 phase into an unknown low temperature phase, possibly the monoclinic space group P1121. Small peaks in the dielectric constants [epsilon]a and [epsilon]b have been observed at this transition temperature. [less ▲]

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See detailEvidence for structural transformations in polymer melts
Krüger, Jan-Kristian UL; Peetz, L.; Wildner, W. et al

in Polymer (2009), 21(6), 620-626

Crystallizing and non-crystallizing polymers have been investigated by Brillouin spectroscopy in the liquid state. The temperature gradient of the sound velocity of crystallizing polymers shows a ... [more ▼]

Crystallizing and non-crystallizing polymers have been investigated by Brillouin spectroscopy in the liquid state. The temperature gradient of the sound velocity of crystallizing polymers shows a discontinuity at ~60-110K above the melting transition. The non-crystallizing polymers investigated show no uniform behaviour. We interpret the phase between the melt temperature and the temperature of the additional transformation as a phase of locally nematic structure. This interpretation is also supported by a study of density, refractive index, viscosity and hypersonic attenuation. [less ▲]

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See detailEvidence for the formation of nanoprecipitates with magnetically disordered regions in bulk Ni50Mn45In5 Heusler alloys
Benacchio, G.; Titov, Ivan UL; Malyeyev, Artem UL et al

in Physical Review. B, Condensed Matter and Materials Physics (2019), 99

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See detailEvidence for the homothetic scaling of urban forms
Lemoy, Rémi UL; Caruso, Geoffrey UL

Scientific Conference (2017, September)

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See detailEvidence for the homothetic scaling of urban forms
Lemoy, Rémi UL; Caruso, Geoffrey UL

in Environment and Planning B: Urban Analytics and City Science (2018)

The size and form of cities influence their social and environmental impacts. Whether cities have the same form irrespective of their size is still an open question. We analyse the profile of artificial ... [more ▼]

The size and form of cities influence their social and environmental impacts. Whether cities have the same form irrespective of their size is still an open question. We analyse the profile of artificial land and population density, with respect to the distance to their main centre, for the 300 largest European cities. Our analysis combines the GMES/Copernicus Urban Atlas 2006 land use database at 5 m resolution for 300 larger urban zones with more than 100,000 inhabitants and the Geostat population grid at 1 km resolution. We find a remarkable constancy of radial profiles across city sizes. Artificial land profiles scale in the two horizontal dimensions with the square root of city population, while population density profiles scale in three dimensions with its cube root. In short, cities of different size are homothetic in terms of land use and population density, which challenges the idea that larger cities are more parsimonious in the use of land per capita. While earlier literature documented the scaling of average densities (total surface and population) with city size, we document the scaling of the whole radial distance profile with city size, thus liaising intra-urban radial analysis and systems of cities. Our findings also yield homogenous spatial definitions of cities, from which we can re-question urban scaling laws and Zipf’s law for cities. [less ▲]

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See detailEvidence for the interaction of mast cell-degranulating peptide with pertussis toxin-sensitive G proteins in mast cells
Mousli, M.; Bronner, C.; Bueb, Jean-Luc UL et al

in European Journal of Pharmacology (1991), 207(3), 249-55

K(+)-channel blocker properties have been reported for mast cell-degranulating peptide (MCD) in the central nervous system, but its action mechanism in mast cells remains unknown. We studied the effect of ... [more ▼]

K(+)-channel blocker properties have been reported for mast cell-degranulating peptide (MCD) in the central nervous system, but its action mechanism in mast cells remains unknown. We studied the effect of MCD on the membrane potential of rat peritoneal mast cells using the fluorescent probe bis-oxonol. Unexpectedly, MCD induced a decrease in bis-oxonol fluorescence, in a rapid and then a slower phase, suggesting hyperpolarization of mast cells. Other K(+)-channel blockers, tetraethylammonium and 4-aminopyridine, did not significantly modify the bis-oxonol fluorescence and did not alter the effect of MCD. The late phase of bis-oxonol fluorescence decrease was inhibited by ouabain and by potassium deprivation, whereas histamine release was not affected. The first phase of putative hyperpolarization induced by MCD coincided with histamine release and with the generation of inositol polyphosphates. Prior treatment of the cells with pertussis toxin inhibited these effects of MCD. MCD stimulated the GTPase activity of purified G proteins (G0/Gi) in a concentration-dependent manner. These results indicate that the effect of MCD on mast cells is unrelated to K+ channels but that it is relevant to the activation of pertussis toxin-sensitive G proteins leading to the activation of phospholipase C. A direct interaction of MCD with G proteins is proposed, which, unlike mastoparan, does not require positive cooperativity. [less ▲]

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See detailEvidence for the involvement of calcitonin gene-related peptide in the epithelium-dependent contraction of guinea-pig trachea in response to capsaicin
Tschirhart, Eric UL; Bertrand, C.; Theodorsson, E. et al

in Naunyn-Schmiedeberg's Archives of Pharmacology (1990), 342(2), 177-81

Capsaicin (10(-9) to 10(-5) M) contracted guinea-pig tracheal strips. Epithelium-containing tracheal strips developed a maximum active tension which was significantly higher than that observed in ... [more ▼]

Capsaicin (10(-9) to 10(-5) M) contracted guinea-pig tracheal strips. Epithelium-containing tracheal strips developed a maximum active tension which was significantly higher than that observed in epithelium-free strips. Anti-CGRP (calcitonin gene-related peptide) serum blocked the epithelium-dependent potentiation of the capsaicin-induced contraction in the intact tracheal strips, without affecting the response of the epithelium-free strips. This result suggests the occurrence of an epithelium-dependent release of CGRP. This same serum markedly reduced the contraction induced by exogenous rat CGRP in both intact and epithelium-free tracheal strips. In epithelium-free tracheal strips, capsaicin-induced contraction was abolished by spantide (10(-6) and 10(-5) M), a substance P antagonist, but, in intact tracheal strips, spantide did not abolish the capsaicin-induced contraction, showing that both CGRP and substance P release are directly induced by capsaicin. Moreover, the contractile responses to rat CGRP of intact tracheal strips from guinea pig suggest that CGRP itself might be able to release a contracting factor from the airway epithelium. Therefore, CGRP originating from the airway epithelium may play a major role in the control of airway smooth muscle tone. [less ▲]

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See detailEvidence from site-directed mutagenesis that the cytoplasmic domain of the beta3 subunit influences the conformational state of the alphaVbeta3 integrin ectodomain.
Schaffner-Reckinger, Elisabeth UL; Brons, N. H.; Kieffer, N.

in Thrombosis and haemostasis (2001), 85(4), 716-23

In order to explore the mechanisms leading to conformational changes of the vitronectin receptor alphavbeta3 following ligand or divalent cation binding, we have investigated the expression of epitopes ... [more ▼]

In order to explore the mechanisms leading to conformational changes of the vitronectin receptor alphavbeta3 following ligand or divalent cation binding, we have investigated the expression of epitopes known as ligand-induced binding sites (LIBS) on beta3 cytoplasmic tail mutants expressed in CHO cells. Truncation of the entire beta3 cytoplasmic domain induced constitutive LIBS exposure on alphavbeta3 and alphaIIbeta3. Deletion of the C-terminal NITY759 sequence or disruption of the NPLY747 motif by a Y747A substitution impaired extracellular conformational changes on alphavbeta3 following RGDS, echistatin or Mn2+ binding, whereas the substitutions Y747F, Y759A or Y759F allowed normal LIBS exposure. Furthermore, metabolic energy depletion totally prevented Mn2+-dependent LIBS exposure, but had only a minor effect on RGDS-induced conformational changes. Our results demonstrate that the structural integrity of the NPLY747 motif in the beta3 cytoplasmic domain, rather than potential phosphorylation of Tyr747 or Tyr759, is a prerequisite for conformational changes within the alphavbeta3 ectodomain, and suggest that two different mechanisms are responsible for RGDS- and Mn2+-dependent conformational changes. [less ▲]

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See detailEvidence management for compliance of critical systems with safety standards: A survey on the state of practice
Nair, Sunil; de la Vara, Jose Luis; Sabetzadeh, Mehrdad UL et al

in Information & Software Technology (2015), 60

Context Demonstrating compliance of critical systems with safety standards involves providing convincing evidence that the requirements of a standard are adequately met. For large systems, practitioners ... [more ▼]

Context Demonstrating compliance of critical systems with safety standards involves providing convincing evidence that the requirements of a standard are adequately met. For large systems, practitioners need to be able to effectively collect, structure, and assess substantial quantities of evidence. Objective This paper aims to provide insights into how practitioners deal with safety evidence management for critical computer-based systems. The information currently available about how this activity is performed in the industry is very limited. Method We conducted a survey to determine practitioners’ perspectives and practices on safety evidence management. A total of 52 practitioners from 15 countries and 11 application domains responded to the survey. The respondents indicated the types of information used as safety evidence, how evidence is structured and assessed, how evidence evolution is addressed, and what challenges are faced in relation to provision of safety evidence. Results Our results indicate that (1) V&V artefacts, requirements specifications, and design specifications are the most frequently used safety evidence types, (2) evidence completeness checking and impact analysis are mostly performed manually at the moment, (3) text-based techniques are used more frequently than graphical notations for evidence structuring, (4) checklists and expert judgement are frequently used for evidence assessment, and (5) significant research effort has been spent on techniques that have seen little adoption in the industry. The main contributions of the survey are to provide an overall and up-to-date understanding of how the industry addresses safety evidence management, and to identify gaps in the state of the art. Conclusion We conclude that (1) V&V plays a major role in safety assurance, (2) the industry will clearly benefit from more tool support for collecting and manipulating safety evidence, and (3) future research on safety evidence management needs to place more emphasis on industrial applications. [less ▲]

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See detailEvidence on the Impact of Education on Social Progress
Samuel, Robin UL

Scientific Conference (2012)

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See detailEvidence on the Insurance Effect of Marginal Income Taxes
Grant, Charles; Koulovatianos, Christos UL; Michaelides, Alexander et al

Report (2008)

Marginal income taxes may have an insurance effect by decreasing the effective fluctuations of after-tax individual income. By compressing the idiosyncratic component of personal income fluctuations ... [more ▼]

Marginal income taxes may have an insurance effect by decreasing the effective fluctuations of after-tax individual income. By compressing the idiosyncratic component of personal income fluctuations, higher marginal taxes should be negatively correlated with the dispersion of consumption across households, a necessary implication of an insurance effect of taxation. Our study empirically examines this negative correlation, exploiting the ample variation of state taxes across US states. We show that taxes are negatively correlated with the consumption dispersion of the within-state distribution of non-durable consumption and that this correlation is robust. [less ▲]

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See detailEvidence on the Insurance Effect of Redistributive Taxation
Koulovatianos, Christos UL; Grant, Charles; Michaelides, Alexander et al

in Review of Economics and Statistics (2010), 92(1), 965-973

If households face uninsurable idiosyncratic earnings risk, theory predicts that re- distributive tax and transfer systems have both an insurance and a distortionary e®ect. Exploiting the substantial ... [more ▼]

If households face uninsurable idiosyncratic earnings risk, theory predicts that re- distributive tax and transfer systems have both an insurance and a distortionary e®ect. Exploiting the substantial variation of tax and transfer systems across US states and over time we investigate the necessary traces of these two effects in the data: that state-level measures of redistributive taxation should correlate negatively with, (a) the standard deviation, and (b) the mean, of the within-state consumption distribution. We find that the first correlation is robust, supporting strongly the presence of an insurance effect. The distortionary effect can also be detected in the data but it is less precisely estimated. [less ▲]

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See detailEvidence that cortisol-induced increase in baroreflex sensitivity of heart rate control is not due to afferent visceral neurotransmission
Schulz, André UL; Richter, S.; Schächinger, H.

in 7th World Congress on Stress: Program and Abstracts (2010)

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See detailEvidence that stress effects on interoception depend on attentional factors
Schulz, André UL; Schachinger, H.

in Abstractband des 30. Symposiums Klinische Psychologie und Psychotherapie (2012)

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See detailEvidence-based recommendations for the development of obesity prevention programs targeted at preschool children
Summerbell, Carolyn; Moore, Helen; Vögele, Claus UL et al

in Obesity Reviews : An Official Journal of the International Association for the Study of Obesity (2012), 13(Suppl 1), 129-132

As previously discussed in other papers in this Supplement of Obesity Reviews, the Toybox intervention was developed using an evidence-based approach, and refined through pilot testing. As part of that ... [more ▼]

As previously discussed in other papers in this Supplement of Obesity Reviews, the Toybox intervention was developed using an evidence-based approach, and refined through pilot testing. As part of that evidence base, two pieces of work were carried out. First, a series of narrative reviews of educational strategies and psychological approaches explaining young children’s acquisition and formation of energy-balance related behaviours, and facilitating their management (Gibson et al1; Vögele et al2; Kreichauf et al3, all published in this supplement). Second, a systematic review to identify behavioural models underpinning school-based interventions in pre-school and school settings for the prevention of obesity in children aged 4-6 years (Nixon et al4; published in this supplement). The aim of this short paper is to summarise and translate the findings from these two reviews into practical evidence-based recommendations for researchers and policy makers to consider when developing and implementing interventions for the prevention of overweight and obesity in young (aged 4-6) children. [less ▲]

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See detailEvidence-Basing the Future of the EHEA
Deca, Ligia UL; Curaj, Adrian; Haj, Mihai Cezar et al

in Journal of the European Higher Education Area (2014), (3),

The EHEA has been launched in 2010 with the wider goal of ensuring more comparable, compatible and coherent systems of higher education in Europe. This initiative, deemed by many observers as one of the ... [more ▼]

The EHEA has been launched in 2010 with the wider goal of ensuring more comparable, compatible and coherent systems of higher education in Europe. This initiative, deemed by many observers as one of the most successful regional cooperation process in the field of higher education policies, relies on soft-coordination mechanisms grounded on the principle of evidence-based policy making (Deca, 2013). The present article aims at illustrating the way in which European level policy decisions have so far been grounded on evidence, while making the case for potential additional tools that could contribute to achieving the EHEA goals: data analytics, semantic analysis and ‘big data’ approaches. [less ▲]

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See detailEvidenz und Werte in Erziehung und Bildung. Drei weitere Defizite evidenzbasierter Praxis
Biesta, Gert UL

in Otto, H.-U.; Polutta, A.; Ziegler, H. (Eds.) What Works - Welches Wissen braucht die Soziale Arbeit? (2010)

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See detailEvidenz, Erziehung und die Politik der Forschung
Biesta, Gert UL

in Bellmann, J.; Müller, T. (Eds.) Wissen was wirkt. Kritik evidenzbasierter Pädagogik. (2011)

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See detailEVIV: An end-to-end verifiable Internet voting system
Joaquim, Rui UL; Ferreira, Paulo; Ribeiro, Carlos

in Computers & Security (2013), 32(0), 170-191

Traditionally, a country’s electoral system requires the voter to vote at a specific day and place, which conflicts with the mobility usually seen in modern live styles. Thus, the widespread of Internet ... [more ▼]

Traditionally, a country’s electoral system requires the voter to vote at a specific day and place, which conflicts with the mobility usually seen in modern live styles. Thus, the widespread of Internet (mobile) broadband access can be seen as an opportunity to deal with this mobility problem, i.e. the adoption of an Internet voting system can make the live of voter’s much more convenient; however, a widespread Internet voting systems adoption relies on the ability to develop trustworthy systems, i.e. systems that are verifiable and preserve the voter’s privacy. Building such a system is still an open research problem. Our contribution is a new Internet voting system: EVIV, a highly sound End-to-end Verifiable Internet Voting system, which offers full voter’s mobility and preserves the voter’s privacy from the vote casting PC even if the voter votes from a public PC, such as a PC at a cybercafe´ or at a public library. Additionally, EVIV has private vote verificationmechanisms, in which the voter just has to perform a simple match of two small strings (4-5 alphanumeric characters), that detect and protect against vote manipulations both at the insecure vote client platform and at the election server side. [less ▲]

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See detailEvolution and Neural Networks – Protein Secondary Structure Prediction Above 71% Accuracy
Rost, B.; Sander, C.; Schneider, Reinhard UL

in Proceedings of the 27th Hawaii International Conference on System Sciences, Vol. V, Biotechnology Computing (1994)

Detailed reference viewed: 37 (0 UL)