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See detailDu « Plakert » au cerf bleu
Spirinelli, Fabio UL

Article for general public (2017)

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See detailDu ‘Cycle de Minuit’ à la liberté du romancier : la permanence et le mouvement dans l’écriture roualdienne
Freyermuth, Sylvie UL

in Marillaud et Gauthier, Pierre et Robert (Ed.) Ecritures évolutives : entre transgression et innovation (2010)

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See detailDual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation
Hauss, Frederique; Liu, Jiawei; Michelucci, Alessandro UL et al

in Bioorganic & Medicinal Chemistry Letters (2007), 17(15), 4218-4222

The synthesis of resveratrol fatty alcohols (RFAs), a new class of small molecules presenting strong potential for the treatment of neurological diseases, is described. RFAs, hybrid compounds combining ... [more ▼]

The synthesis of resveratrol fatty alcohols (RFAs), a new class of small molecules presenting strong potential for the treatment of neurological diseases, is described. RFAs, hybrid compounds combining the resveratrol nucleus and omega-alkanol side chains, are able to modulate neuroinflammation and to induce differentiation of neural stem cells into mature neurons. Acting on neuroprotection and neuroregeneration, RFAs represent an innovative approach for the treatment or cure of neuropathies. [less ▲]

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See detailThe dual Bonahon-Schläfli formula
Mazzoli, Filippo UL

E-print/Working paper (2018)

Given a differentiable deformation of geometrically finite hyperbolic 3-manifolds (M_t)_t, the Bonahon-Schläfli formula expresses the derivative of the volume of the convex cores (CM_t)_t in terms of the ... [more ▼]

Given a differentiable deformation of geometrically finite hyperbolic 3-manifolds (M_t)_t, the Bonahon-Schläfli formula expresses the derivative of the volume of the convex cores (CM_t)_t in terms of the variation of the geometry of its boundary, as the classical Schläfli formula does for the volume of hyperbolic polyhedra. Here we study the analogous problem for the dual volume, a notion that arises from the polarity relation between the hyperbolic space H^3 and the de Sitter space dS^3. The corresponding dual Bonahon-Schläfli formula has been originally deduced from Bonahon's work by Krasnov and Schlenker. Here, making use of the differential Schläfli formula and the properties of the dual volume, we give a (almost) self-contained proof of the dual Bonahon-Schläfli formula, without making use of Bonahon's original result. [less ▲]

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See detailA dual control approach for repeated anticipatory traffic control with estimation of network flow sensitivity
Huang, Wei; Viti, Francesco UL; Tampere, Chris

in Journal of Advanced Transportation (2016)

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See detailDual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors
Lorendeau, Doriane; Rinaldi, Gianmarco; Boon, Ruben et al

in Metabolic Engineering (2016)

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See detailDual pairs in the Pin-group and duality for the corresponding spinorial representation
Guerin, Clément UL; Liu, Gang; Merino, Allan

E-print/Working paper (2019)

In this paper, we give a complete picture of Howe correspondence for the setting (O(E,b),Pin(E,b),Π), where O(E,b) is an orthogonal group (real or complex), Pin(E,b) is the two-fold Pin-covering of O(E,b ... [more ▼]

In this paper, we give a complete picture of Howe correspondence for the setting (O(E,b),Pin(E,b),Π), where O(E,b) is an orthogonal group (real or complex), Pin(E,b) is the two-fold Pin-covering of O(E,b), and Π is the spinorial representation of Pin(E,b). More precisely, for a dual pair (G,G′) in O(E,b), we determine explicitly the nature of its preimages (G̃,G′~) in Pin(E,b), and prove that apart from some exceptions, (G̃,G′~) is always a dual pair in Pin(E,b); then we establish the Howe correspondence for Π with respect to (G̃,G′~). [less ▲]

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See detailDual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation
Haan, Serge UL; Margue, Christiane UL; Engrand, A. et al

in Journal of Immunology (2008), 180(2), 998-1007

Jak1 is a tyrosine kinase that noncovalently forms tight complexes with a variety of cytokine receptors and is critically involved in signal transduction via cytokines. Jaks are predicted to have a 4.1 ... [more ▼]

Jak1 is a tyrosine kinase that noncovalently forms tight complexes with a variety of cytokine receptors and is critically involved in signal transduction via cytokines. Jaks are predicted to have a 4.1, ezrin, radixin, moesin (FERM) domain at their N terminus. FERM domains are composed of three structurally unrelated subdomains (F1, F2, and F3) which are in close contact to one another and form the clover-shaped FERM domain. We generated a model structure of the Jak1 FERM domain, based on solved FERM structures and the alignments with other FERM domains. To destabilize different subdomains and to uncover their exact function, we mutated specific hydrophobic residues conserved in FERM domains and involved in hydrophobic core interactions. In this study, we show that the structural integrity of the F2 subdomain of the FERM domain of Jak1 is necessary to bind the IFN-gammaRalpha. By mutagenesis of hydrophobic residues in the hydrophobic core between the three FERM subdomains, we find that the structural context of the FERM domain is necessary for the inhibition of Jak1 phosphorylation. Thus, FERM domain mutations can have repercussions on Jak1 function. Interestingly, a mutation in the kinase domain (Jak1-K907E), known to abolish the catalytic activity, also leads to an impaired binding to the IFN-gammaRalpha when this mutant is expressed at endogenous levels in U4C cells. Our data show that the structural integrity of both the FERM domain and of the kinase domain is essential for both receptor binding and catalytic function/autoinhibition. [less ▲]

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See detailDual Study Programmes in Global Context: Internationalisation in Germany and Transfer to Brazil, France, Qatar, Mexico and the US
Graf, Lukas UL; Powell, Justin J W UL; Fortwengel, Johann et al

Book published by DAAD (2014)

This exploratory study is devoted in equal measure to the status quo and the future perspectives of the internationalisation of dual study programmes, a special hybrid form of vocational training and ... [more ▼]

This exploratory study is devoted in equal measure to the status quo and the future perspectives of the internationalisation of dual study programmes, a special hybrid form of vocational training and higher education developed in Germany. Building on the earlier DAAD studies ‘Sachstand: Duales Studium als Exportmodell’ (Maschke 2012) and ‘Modelle und Szenarien für den Export deutscher Studienangebote ins Ausland’ (Schreiterer and Witte 2001; see also DAAD/HRK 2012), the authors examine both the degree of internationalisation of existing dual study programmes in Germany (with special emphasis on students’ geographical mobility) and the possibilities and limits of systematically transferring this emergent educational model to selected countries. Two recent trends have helped put issues of internationalisation and the transfer of German education concepts higher up on the policy agenda again: first, the current economic situation in Germany, which has remained robust despite the recent financial and economic turmoil, reflected most importantly in comparatively low levels of youth unemployment. Dual vocational education and training models are seen as a key factor contributing to this success. Second, the concept of dual studies reflects an emergent model of skill formation at the nexus of initial vocational training and tertiary education. This innovative hybrid form is seen as having the potential to play a crucial role in the development of competencies for twenty-first-century occupations, not least against the backdrop of the pressing skills gap. [less ▲]

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See detailThe dual volume of quasi-Fuchsian manifolds and the Weil-Petersson distance
Mazzoli, Filippo UL

E-print/Working paper (2019)

Making use of the dual Bonahon-Schläfli formula, we prove that the dual volume of the convex core of a quasi-Fuchsian manifold M is bounded by an explicit constant, depending only on the topology of M ... [more ▼]

Making use of the dual Bonahon-Schläfli formula, we prove that the dual volume of the convex core of a quasi-Fuchsian manifold M is bounded by an explicit constant, depending only on the topology of M, times the Weil-Petersson distance between the hyperbolic structures on the upper and lower boundary components of the convex core of M. [less ▲]

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See detailA Dual-Grid Multiscale Approach to CFD-DEM Couplings for Multiphase Flow
Pozzetti, Gabriele UL

Doctoral thesis (2018)

This thesis focuses on a novel dual-grid multiscale approach to CFD- DEM1 couplings, proposes its advantages in terms of numerical proper- ties and performance, and provides examples of engineering ... [more ▼]

This thesis focuses on a novel dual-grid multiscale approach to CFD- DEM1 couplings, proposes its advantages in terms of numerical proper- ties and performance, and provides examples of engineering applications that can benefit from it. In recent years, CFD-DEM couplings are be- coming a more and more adopted solution for the numerical simulation of particle-laden flows. In particular, couplings based on the volume av- eraging technique have become a standard for numerical simulations in chemical and process engineering. Furthermore, they are rapidly spread- ing to civil, geotechnical and mechanical applications due to their ability in dealing with arbitrarily complex mixtures of continuum and granular media. Despite the several advantages that these Eulerian-Lagrangian cou- plings provide, their rigorous application to complex scenarios is currently limited by two main factors. First, the computational traceability of the solutions can become problematic due to the lack of a general theory on the subject. In particular, grid-convergence studies for the solution of the continuous phases are often not feasible due to the averaging procedure that imposes limitations on the grid structure and refinement. Second, the parallel implementation of these numerical schemes holds important disadvantages in terms of memory consumption and inter-physics com- munication load. These disadvantages are significantly limiting the ex- tension of these approaches to large-scale scenarios. This thesis collects some of the most significant works published in the last years on a novel approach that allows solving the two above- mentioned problems, and, therefore, tackling more complex and expen- sive scenarios. I refer to this approach as dual-grid multiscale approach for CFD-DEM couplings. It consists in using two different computational grids, one for the coupling between continuum and discrete entities and one for the solution of the so-obtained continuum equations. The two grids, i.e. the two problems, are in this way resolved on two different scales. The first scale or “bulk” scale is chosen to optimize the averag- ing operation. At this length-scale, the discrete entities are considered as zero-dimensional, and interact with the fluid with local exchanges of momentum, mass, and energy. The second scale or “fluid-fine” scale is identified as the one at which a unique solution for the averaged equa- tions can be provided. In practice, this is chosen as the one at which the solution of the fluid equations becomes grid-independent. An inter-scale communication is adopted by interpolating fields from the fluid-fine scale to the bulk one and vice-versa. The theoretical description of the method is first provided with par- ticular reference to the DEM-VOF coupling. Even in its simplest version, the multiscale approach is shown to generate grid-convergent solutions and significantly higher accuracy than a standard CFD-DEM coupling. This shows how the new approach is able to overcome the first main limitation described above. Then, an optimized parallel implementation of the method is pro- posed to show how this multiscale approach can provide significant ben- efits also for what concerns the execution time. Technically, this is made possible by moving the communication cost of the coupling from the inter-physics communication that characterized the standard CFD-DEM couplings to an optimized inter-scale communication routine. This en- ables the method to overcome a major bottleneck of the parallel execution of CFD-DEM couplings and therefore the second main limitation of those schemes. Finally, the dual-grid multiscale method is applied to approach in- dustrially relevant problems that were till now out-of-reach for standard CFD-DEM couplings, proving how this technique can have direct real- case application and produce immediate benefits for practitioners willing to adopt it. [less ▲]

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See detailDual-mode quasi-logarithmic quantizer with embedded G.711 codec
Denic, Bojan; Peric, Zoran; Despotovic, Vladimir UL et al

in Journal of Electrical Engineering (2018), 69(1), 46-51

The G.711 codec has been accepted as a standard for high quality coding in many applications. A dual-mode quantizer, which combines the nonlinear logarithmic quantizer for restricted input signals and G ... [more ▼]

The G.711 codec has been accepted as a standard for high quality coding in many applications. A dual-mode quantizer, which combines the nonlinear logarithmic quantizer for restricted input signals and G.711 quantizer for unrestricted input signals is proposed in this paper. The parameters of the proposed quantizer are optimized, where the minimal distortion is used as the criterion. It is shown that the optimized version of the proposed quantizer provides 5.4 dB higher SQNR (Signal to Quantization Noise Ratio) compared to G.711 quantizer, or equivalently it performs savings in the bit rate of approximately 0.9 bit/sample for the same signal quality. Although the complexity is slightly increased, we believe that due to the superior performance it can be successfully implemented for high-quality quantization. [less ▲]

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See detailDual-Use Research In Ransomware Attacks: A Discussion on Ransomware Defence Intelligence
Genç, Ziya Alper UL; Lenzini, Gabriele UL

in Proceedings of the 6th International Conference on Information Systems Security and Privacy (2020)

Previous research has shown that developers rely on public platforms and repositories to produce functional but insecure code. We looked into the matter for ransomware, enquiring whether also ransomware ... [more ▼]

Previous research has shown that developers rely on public platforms and repositories to produce functional but insecure code. We looked into the matter for ransomware, enquiring whether also ransomware engineers re-use the work of others and produce insecure code. By methodically reverse-engineering 128 malware executables, we have found that, out of 21 ransomware samples, 9 contain copy-paste code from public resources. Thanks to this finding, we managed to retrieve the decryption keys with which to nullify the ransomware attacks. From this fact, we recall critical cases of code disclosure in the recent history of ransomware and, arguing that ransomware are components in cyber-weapons, reflect on the dual-use nature of this research. We further discuss benefits and limits of using cyber-intelligence and counter-intelligence strategies that could be used against this threat. [less ▲]

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See detailDuale Prozessmodelle der sozialen Urteilsbildung
Böhmer, Ines; Böhmer, Matthias UL

in Südkamp, Anna; Praetorius, Anna-Katharina (Eds.) Diagnostische Kompetenz von Lehrkräften: Theoretische und methodische Weiterentwicklungen (2015, March)

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See detailDuale Studiengänge als „unerwartete“ Form der institutionellen Durchlässigkeit zwischen Berufs- und Hochschulbildung in Deutschland
Graf, Lukas UL

in Solga, Heike; Brzinsky-Fay, Christian; Graf, Lukas (Eds.) et al Vergleiche innerhalb von Gruppen und institutionelle Gelingensbedingungen. Vielversprechende Perspektiven für die Ungleichheitsforschung (2013)

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See detailA duality for Moore groups
Kuznetsova, Julia UL

in Journal of Operator Theory (2013), 69(2), 571-600

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See detailA Duality for the Algebras of a Łukasiewicz n + 1-valued Modal System
Teheux, Bruno UL

in Studia Logica (2007), 87(1), 13-36

n this paper, we develop a duality for the varieties of a Łukasiewicz n + 1-valued modal system. This duality is an extension of Stone duality for modal algebras. Some logical consequences (such as ... [more ▼]

n this paper, we develop a duality for the varieties of a Łukasiewicz n + 1-valued modal system. This duality is an extension of Stone duality for modal algebras. Some logical consequences (such as completeness results, correspondence theory...) are then derived and we propose some ideas for future research. [less ▲]

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See detailA duality of locally compact groups which does not involve the Haar measure
Kuznetsova, Julia UL

E-print/Working paper (2012)

Detailed reference viewed: 23 (0 UL)