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See detailThe Discourse of German Geisteswissenschaftliche Pädagogik - A Contextual Reconstruction
Tröhler, Daniel UL

in Paedagogica Historica (2003), XXXIX(6), 759-778

The framework of German educational discourse of the twentieth century is so-called geisteswissenschaftliche Pädagogik, or education as one of the humanities or arts rather than as a science. It triumphed ... [more ▼]

The framework of German educational discourse of the twentieth century is so-called geisteswissenschaftliche Pädagogik, or education as one of the humanities or arts rather than as a science. It triumphed around 1925 in the second half of the Weimar Republic. This article outlines in three steps the core elements of this educational discourse. [less ▲]

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See detailThe discourse of lending aid on small-scale development project websites: Dutch depreciatory diminutives
Juffermans, Kasper UL

in Language Matters: Studies in the Languages of Africa (2008), 39(1), 125-144

This article offers an analysis of the use of language on the websites of Dutch and Flemish small-scale development organisations active in The Gambia. The scope of this research is the websites of 66 ... [more ▼]

This article offers an analysis of the use of language on the websites of Dutch and Flemish small-scale development organisations active in The Gambia. The scope of this research is the websites of 66 organisations found through the hyperlink page http://gambia-hulporganisaties.startpagina.nl. The texts on the websites form a small corpus of around 375 000 words. Methodologically, a discourse-analytical perspective is assumed, heuristically assisted by corpus linguistic software. Thus, the texts are analysed simultaneously from a macro and micro-level: large-scale lexical patterns are combined with smaller-scale, contextualised, individual chunks of text. After a brief outline of the projects’ roots in tourism through self-reported histories of involvement and a cursory review of the literature on meanings and functions of diminutives in Dutch and other languages, the role of diminutives in the representation of the Third-World Other is explored. It is argued that diminutives in this context are used in an ambivalent way: diminutives express a sense of sympathy and at the same time reveal a derogative tone in descriptions of the Gambian side of the projects. [less ▲]

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See detailThe discourse structure of literature review paragraphs: a multilingual study
Deroey, Katrien UL; Huemer, Birgit UL; Lejot, Eve UL

in Schreibwissenschaft (2019)

This paper examines literature reviews in 12 master’s dissertations written in German, English and French. Specifically, we analysed the discourse structure of 155 paragraphs to assess the extent to which ... [more ▼]

This paper examines literature reviews in 12 master’s dissertations written in German, English and French. Specifically, we analysed the discourse structure of 155 paragraphs to assess the extent to which students manage to write a coherent review combining literature reports with their own ‘voice’. The study was motivated by the design of a multilingual academic writing course at the University of Luxembourg Language Centre. The analysis distinguished three main discourse elements, nl. report, discussion and text orientation. The data reveal considerable variation in the frequency with which these combine to form different paragraph types. However, in all three languages, report discourse uses the same quotation and reformulation strategies and tends to employ ‘list’ structures with few cohesive links. Discussion elements are generally not elaborated and the writer’s voice is weak. Text organization uses the same linguistic strategies and is mainly used to orientate readers rather than to summarize or signal transitions. Pedagogical implications for multilingual academic writing courses are discussed. [less ▲]

Detailed reference viewed: 259 (9 UL)
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See detailDiscourse Yes, Implementation Maybe: an Immobility and Paralysis of Sustainable Development Policy
Carr, Constance UL

in European Planning Studies (2014), 22(9), 1824-1840

Sustainable development policies are on the move. Cities the world over are reposition-ing, repackaging and remarketing themselves as green and sustainable, and sustainable development is the moniker ... [more ▼]

Sustainable development policies are on the move. Cities the world over are reposition-ing, repackaging and remarketing themselves as green and sustainable, and sustainable development is the moniker imported to spark the process. At the same time, sustainable development, as a normative point of departure, is itself going through cycles of reinterpretation and re-composition. The research in this paper aims to understand this process by mapping the trajectories of sustainable development policies, and understanding sustainable development as a contextually grounded policy in motion. In Luxembourg, as planners are confronted with finding ways to manage growth, sustainable development has come to permeate all levels of the planning system. To understand how this came into being, research methods were employed that include document screening and a series of conversational interviews that were later transcribed and coded. In so doing, the discourse around sustainable development policy could be reconstructed and analysed. The results showed that the multi-scalar, cross-national, and simultaneously micro-level governance structures pose many obstructions to the implementation of sustainable development policies that are imported from abroad. Thus, policy is ultimately immobile, and a policy paralysis can be spoken of. [less ▲]

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See detailDiscourses of border crossers: Peruvian domestic workers in Lima as promoters of integration in Peru?
Mick, Carola UL

in Discourse Studies (2011), 13(2), 189-209

This article is based on narrative, autobiographic interviews with domestic workers in Peru focusing on their migration and work experiences. The interviewees evoke a border discourse that divides and ... [more ▼]

This article is based on narrative, autobiographic interviews with domestic workers in Peru focusing on their migration and work experiences. The interviewees evoke a border discourse that divides and hierarchizes Peruvian society and stigmatizes migrants, especially migrant domestic workers. As domestic service leads to intense social interactions at this ‘border’, the interviewees are constantly forced to ‘translate’ (Bhabha, 1996) when constructing their identity. The discourse-analytical bottom–up perspective focusing on membership categorization devices evaluates the performativity of the discourses of those considered as ‘oppressed’; it analyses processes of subjection and subjectification: whereas some of the interviewees internalize the discursively attributed inferior ‘Me’, others use the constructed borders as an opportunity to develop hybrid discourse strategies that cross and even deconstruct social categorizations. By focusing on the agency of ‘border-crossers’, the article aims at scientifically ‘rethinking the social with cultural difference as a constitutive feature’ (Papastergiadis, 2000: 18). [less ▲]

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See detailDiscourses of sexual relationships in a sample of German and British young people: A Q methodological study
Franz, Anke; Worrell, Marcia; Vögele, Claus UL

in Culture, Health and Sexuality (2016), 18(4), 391-404

Young people live in an environment, which sexualises young people, particularly women, along traditional gender roles. This, in parallel with a silence about positive sexuality in policy development ... [more ▼]

Young people live in an environment, which sexualises young people, particularly women, along traditional gender roles. This, in parallel with a silence about positive sexuality in policy development, means that sexual double standards prevail in young people’s lives. The aim of this study was to explore the discourses young women and men from two European countries, Germany and England, draw on when making sense of sexual relationships, and how these are steeped in the local cultural climate and messages. The study used Q methodology and included 65 German and English young people between 16 and 19 years of age. Six accounts emerged: sex as responsible, intimate and shared experience; sex as joint fun; ideal versus reality; sex has to be responsible, consensual and shared; caring relationships offer the perfect context for fulfilling sex; and equality between partners. The importance of cultural context in the availability of specific dominant and alternative discourses is discussed with a focus on how this influences young people’s sense-making with regard to sexuality and sexual relationships. Future directions for research are highlighted. [less ▲]

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See detailDISCOV: Encouraging a Healthy Active Lifestyle through the Design of Interactive Environments.
van Renswouw, Loes; Verhoef, Jasmijn; Vos, Steven et al

Scientific Conference (2021, June)

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See detailDISCOV: Stimulating Physical Activity through an Explorative Interactive Walking Experience
van Renswouw, Loes; Verhoef, Jasmijn; Vos, Steven et al

in IASDR 2021: 9th Congress of the International Association of Societies of Design Research (in press)

Aware of the consequences of their inactive lifestyles, many people still struggle to integrate enough physical activity into their busy lives. Interventions that nudge to reinforce existing active ... [more ▼]

Aware of the consequences of their inactive lifestyles, many people still struggle to integrate enough physical activity into their busy lives. Interventions that nudge to reinforce existing active behavior seem therefore more likely to be effective than those adding an activity to daily routines. To encourage people to increase their physical activity level, we designed Discov, a network of physical waypoints triggering people to lengthen their walks. Placed in a public park, Discov encourages people to explore their surroundings in a fun and challenging way by creating an interactive walking experience. Adopting a Research-through-Design approach, we explore the potential of the design of accessible infrastructures and human-environment interactions to impact public health by nudging citizens into being more physically active. We discuss insights gathered through this process and report on first user tests of this interactive walking experience. [less ▲]

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See detailDISCOVER: A Unified Protocol for Data Dissemination and Collection in VANETs
Turcanu, Ion UL; Salvo, Pierpaolo; Baiocchi, Andrea et al

in Proceedings of the 12th ACM Symposium on Performance Evaluation of Wireless Ad Hoc, Sensor, \&\#38; Ubiquitous Networks (2015, November)

Message dissemination and data collection from vehicles are two key enablers of Intelligent Transportation System services that can be offered by a Vehicular Ad-Hoc Network (VANET) technology. In this ... [more ▼]

Message dissemination and data collection from vehicles are two key enablers of Intelligent Transportation System services that can be offered by a Vehicular Ad-Hoc Network (VANET) technology. In this work we propose a fully distributed protocol for dissemination of query and collection of reply messages carrying information gathered from vehicles moving in a given target area, in an urban scenario. The key idea is to use the dissemination phase (forward wave) to create a network of relay nodes that are in charge of delivering reply messages back to the originating point (reverse wave). The proposed protocol is evaluated with reference to two real urban environments. Main parameters are dimensioned and an insight in the protocol working is given. [less ▲]

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See detailDiscovering ePassport Vulnerabilities using Bisimilarity
Horne, Ross James UL; Mauw, Sjouke UL

in Logical Methods in Computer Science (2021), 17(2), 241--2452

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See detailDiscovering Everyday Mathematical Situations Outside the Classroom with MathCityMap and GeoGebra 3D
Lavicza, Zsolt; Haas, Ben; Kreis, Yves UL

in Ludwig, Matthias; Jablonski, Simone; Caldeira, Amélia (Eds.) et al Research on Outdoor STEM Education in the digiTal Age: Proceedings of the ROSETA Online Conference in June 2020 (2020, June 10)

In elementary school, teaching and learning activities aim to develop, among others, students’ skills to acquire deeper understanding of their living environments. There are numerous opportunities for ... [more ▼]

In elementary school, teaching and learning activities aim to develop, among others, students’ skills to acquire deeper understanding of their living environments. There are numerous opportunities for students to recognize forms, shapes, and mathematical connections in everyday situations. These everyday situations can be simulated in classrooms; however, educational technologies offer new approaches to extend classroom activities, teachers can simulate and design shapes through Augmented Reality and 3D printing within or beyond the classroom. To stimulate students’ everyday mathematical connections utilizing these technologies could assist in developing activities outside the classroom in urban or in natural environments. Through this approach students could utilize or enhance their mathematical and technical skills within their usual living environments. Utilising educational software such as MathCityMap, GeoGebra 3D Calculator, and other 3D modelling software we developed examples of tasks that could offer easy transitions from in- to out-side of classrooms. In this paper, we will describe learning and teaching aims of these tasks and outline further research and development directions to broaden opportunities to develop students’ mathematical, design and modelling skills. [less ▲]

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See detailDiscovering pair-wise genetic interactions: an information theory-based approach.
Ignac, Tomasz UL; Skupin, Alexander UL; Sakhanenko, Nikita A. et al

in PloS one (2014), 9(3), 92310

Phenotypic variation, including that which underlies health and disease in humans, results in part from multiple interactions among both genetic variation and environmental factors. While diseases or ... [more ▼]

Phenotypic variation, including that which underlies health and disease in humans, results in part from multiple interactions among both genetic variation and environmental factors. While diseases or phenotypes caused by single gene variants can be identified by established association methods and family-based approaches, complex phenotypic traits resulting from multi-gene interactions remain very difficult to characterize. Here we describe a new method based on information theory, and demonstrate how it improves on previous approaches to identifying genetic interactions, including both synthetic and modifier kinds of interactions. We apply our measure, called interaction distance, to previously analyzed data sets of yeast sporulation efficiency, lipid related mouse data and several human disease models to characterize the method. We show how the interaction distance can reveal novel gene interaction candidates in experimental and simulated data sets, and outperforms other measures in several circumstances. The method also allows us to optimize case/control sample composition for clinical studies. [less ▲]

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See detailDiscovering pesticides and their TPs in Luxembourg waters using open cheminformatics approaches
Krier, Jessy; Singh, Randolph R.; Kondic, Todor UL et al

in Environment International (2022), 158

The diversity of hundreds of thousands of potential organic pollutants and the lack of (publicly available) information about many of them is a huge challenge for environmental sciences, engineering, and ... [more ▼]

The diversity of hundreds of thousands of potential organic pollutants and the lack of (publicly available) information about many of them is a huge challenge for environmental sciences, engineering, and regulation. Suspect screening based on high-resolution liquid chromatography-mass spectrometry (LC-HRMS) has enormous potential to help characterize the presence of these chemicals in our environment, enabling the detection of known and newly emerging pollutants, as well as their potential transformation products (TPs). Here, suspect list creation (focusing on pesticides relevant for Luxembourg, incorporating data sources in 4 languages) was coupled to an automated retrieval of related TPs from PubChem based on high confidence suspect hits, to screen for pesticides and their TPs in Luxembourgish river samples. A computational workflow was established to combine LC-HRMS analysis and pre-screening of the suspects (including automated quality control steps), with spectral annotation to determine which pesticides and, in a second step, their related TPs may be present in the samples. The data analysis with Shinyscreen (https://gitlab.lcsb.uni.lu/eci/shinyscreen/), an open source software developed in house, coupled with custom-made scripts, revealed the presence of 162 potential pesticide masses and 96 potential TP masses in the samples. Further identification of these mass matches was performed using the open source approach MetFrag (https://msbi.ipb-halle.de/MetFrag/). Eventual target analysis of 36 suspects resulted in 31 pesticides and TPs confirmed at Level-1 (highest confidence), and five pesticides and TPs not confirmed due to different retention times. Spatio-temporal analysis of the results showed that TPs and pesticides followed similar trends, with a maximum number of potential detections in July. The highest detections were in the rivers Alzette and Mess and the lowest in the Sûre and Eisch. This study (a) added pesticides, classification information and related TPs into the open domain, (b) developed automated open source retrieval methods - both enhancing FAIRness (Findability, Accessibility, Interoperability and Reusability) of the data and methods; and (c) will directly support “L’Administration de la Gestion de l’Eau” on further monitoring steps in Luxembourg. [less ▲]

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See detailDiscovering Pesticides and their Transformation Products in Luxembourg Waters using Open Cheminformatics Approaches
Krier, Jessy UL; Singh, Randolph UL; Kondic, Todor UL et al

E-print/Working paper (2021)

Abstract The diversity of hundreds of thousands of potential organic pollutants and the lack of (publicly available) information about many of them is a huge challenge for environmental sciences ... [more ▼]

Abstract The diversity of hundreds of thousands of potential organic pollutants and the lack of (publicly available) information about many of them is a huge challenge for environmental sciences, engineering, and regulation. Suspect screening based on high-resolution liquid chromatography-mass spectrometry (LC-HRMS) has enormous potential to help characterize the presence of these chemicals in our environment, enabling the detection of known and newly emerging pollutants, as well as their potential transformation products (TPs). Here, suspect list creation (focusing on pesticides relevant for Luxembourg, incorporating data sources in 4 languages) was coupled to an automated retrieval of related TPs from PubChem based on high confidence suspect hits, to screen for pesticides and their TPs in Luxembourgish river samples. A computational workflow was established to combine LC-HRMS analysis and pre-screening of the suspects (including automated quality control steps), with spectral annotation to determine which pesticides and, in a second step, their related TPs may be present in the samples. The data analysis with Shinyscreen (https://git-r3lab.uni.lu/eci/shinyscreen/), an open source software developed in house, coupled with custom-made scripts, revealed the presence of 162 potential pesticide masses and 135 potential TP masses in the samples. Further identification of these mass matches was performed using the open source MetFrag (https://msbi.ipb-halle.de/MetFrag/). Eventual target analysis of 36 suspects resulted in 31 pesticides and TPs confirmed at Level-1 (highest confidence), and five pesticides and TPs not confirmed due to different retention times. Spatio-temporal analysis of the results showed that TPs and pesticides followed similar trends, with a maximum number of potential detections in July. The highest detections were in the rivers Alzette and Mess and the lowest in the Sûre and Eisch. This study (a) added pesticides, classification information and related TPs into the open domain, (b) developed automated open source retrieval methods - both enhancing FAIRness (Findability, Accessibility, Interoperability and Reusability) of the data and methods; and (c) will directly support “L’Administration de la Gestion de l’Eau” on further monitoring steps in Luxembourg. [less ▲]

Detailed reference viewed: 48 (3 UL)
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See detailDiscovering Pesticides, Pharmaceuticals TPs in Luxembourg Waters using Open Cheminformatics Approaches
Krier, Jessy; Singh, Randolph R.; Kondic, Todor UL et al

Scientific Conference (2021, June 24)

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See detailDiscovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains.
Espinosa Angarica, Vladimir UL; Ventura, Salvador; Sancho, Javier

in BMC genomics (2013), 14

BACKGROUND: Prion proteins conform a special class among amyloids due to their ability to transmit aggregative folds. Prions are known to act as infectious agents in neurodegenerative diseases in animals ... [more ▼]

BACKGROUND: Prion proteins conform a special class among amyloids due to their ability to transmit aggregative folds. Prions are known to act as infectious agents in neurodegenerative diseases in animals, or as key elements in transcription and translation processes in yeast. It has been suggested that prions contain specific sequential domains with distinctive amino acid composition and physicochemical properties that allow them to control the switch between soluble and beta-sheet aggregated states. Those prion-forming domains are low complexity segments enriched in glutamine/asparagine and depleted in charged residues and prolines. Different predictive methods have been developed to discover novel prions by either assessing the compositional bias of these stretches or estimating the propensity of protein sequences to form amyloid aggregates. However, the available algorithms hitherto lack a thorough statistical calibration against large sequence databases, which makes them unable to accurately predict prions without retrieving a large number of false positives. RESULTS: Here we present a computational strategy to predict putative prion-forming proteins in complete proteomes using probabilistic representations of prionogenic glutamine/asparagine rich regions. After benchmarking our predictive model against large sets of non-prionic sequences, we were able to filter out known prions with high precision and accuracy, generating prediction sets with few false positives. The algorithm was used to scan all the proteomes annotated in public databases for the presence of putative prion proteins. We analyzed the presence of putative prion proteins in all taxa, from viruses and archaea to plants and higher eukaryotes, and found that most organisms encode evolutionarily unrelated proteins with susceptibility to behave as prions. CONCLUSIONS: To our knowledge, this is the first wide-ranging study aiming to predict prion domains in complete proteomes. Approaches of this kind could be of great importance to identify potential targets for further experimental testing and to try to reach a deeper understanding of prions' functional and regulatory mechanisms. [less ▲]

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See detailDiscovering signal transduction networks using signaling domain-domain interactions
Nguyen, Thanh-Phuong UL; Ho, Tu Bao

in Genome Informatics (2006), 17(2), 35--45

Detailed reference viewed: 31 (3 UL)
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See detailDiscovering Students’ Complex Problem Solving Strategies in Educational Assessment
Toth, K.; Greiff, Samuel UL; Wüstenberg, Sascha UL et al

in Proceedings of the 7th International Conference on Educational Data Mining. (pp. 225-228) (2014)

Detailed reference viewed: 62 (5 UL)
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See detailDiscovering the core security requirements of DRM systems by means of objective trees
Jonker, Hugo UL; Mauw, Sjouke UL

in Handbook of Research on Secure Multimedia Distribution (2009)

Detailed reference viewed: 85 (0 UL)