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See detailPhysiological implications of the interaction between the plasma membrane calcium pump and nNOS.
Cartwright, Elizabeth J.; Oceandy, Delvac; Neyses, Ludwig UL

in Pflügers Archiv: European Journal of Physiology (2009), 457(3), 665-71

The tight regulation of intracellular calcium levels is essential for the normal function of a great many cellular processes, and disruption of this regulation, resulting in sustained increases in ... [more ▼]

The tight regulation of intracellular calcium levels is essential for the normal function of a great many cellular processes, and disruption of this regulation, resulting in sustained increases in intracellular-free calcium, has been associated with numerous diseases. One of the several transporters involved in calcium homeostasis is a P-type ATPase known as the plasma membrane calcium/calmodulin-dependent ATPase (PMCA) which is involved in calcium extrusion from the cytosol to the extracellular compartment. It has long been established that in many cell types, in particular non-excitable cells, the primary role of PMCA is in the bulk transport of intracellular calcium; however, its role in excitable cells is less clear. In the heart, for example, calcium is essential for contractile function as well as being a key messenger in signal transduction pathways; however, the mechanisms by which the cardiomyocyte distinguishes between these roles of calcium remain unclear. It is perhaps the transporters not involved in the contractile cycle (such as PMCA) that are able to carry non-contractile signals. This review will highlight the role of PMCA as a modulator of signal transduction pathways and in particular the role of isoform 4 in the regulation of the nitric oxide signalling pathway. [less ▲]

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See detailNicotine Interact With Gabaergic System: Behavioural Evidences?,
Mancuso, Giovanna UL; Tirelli, Ezio

in Pflügers Archiv: European Journal of Physiology (1996), 431(3),

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See detailEffects of nicotine transdermally (patch) on attention working memory and mood
Mancuso, Giovanna UL; Andres, Pilard; Tirelli, Ezio et al

in Pflügers Archiv: European Journal of Physiology (1995), 430

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See detailAdjuvant induced monoarthritis influences SP-mRNA expression in rat dorsal root ganglia
Blecher, Fabian; Hanesch, Ulrike UL; Heppelmann, Bernd et al

in Pflügers Archiv: European Journal of Physiology (1993), 422(Suppl. 1), 50

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See detailDistribution of neurokinin A in articular afferents of the cat
Hanesch, Ulrike UL; Heppelmann, Bernd; Schmidt, Robert

in Pflügers Archiv: European Journal of Physiology (1992), 420(Suppl. 1), 54

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See detailCGRP-immunoreactive nerve fibers in the dura mater encephali of cat and rat
Hanesch, Ulrike UL; Meßlinger, Karl; Schmidt, Robert

in Pflügers Archiv: European Journal of Physiology (1991), 418

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See detailEffect of colchicine treatment on neuropeptide immunoreactivity in cat`s primary articular afferents
Hanesch, Ulrike UL; Heppelmann, Bernd; Schmidt, Robert

in Pflügers Archiv: European Journal of Physiology (1991), 418

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See detailDistribution of somatostatin in primary articular afferents in cat
Hanesch, Ulrike UL; Heppelmann, Bernd; Schmidt, Robert

in Pflügers Archiv: European Journal of Physiology (1990), 415

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See detailMorphometrically verified differences between neurons of the thalamic ventral posteromedial nucleus (VPM) and of its ventral periphery (VPMvp)
Brandt, Heike; Brüggemann, Johannes; Hanesch, Ulrike UL et al

in Pflügers Archiv: European Journal of Physiology (1988), 411

Detailed reference viewed: 39 (1 UL)