Gluing semi-orthogonal decompositions

in Journal of Algebra (2020)

In situ magnetorheological SANS setup at Institut Laue-Langevin

in Colloid and Polymer Science (2020)

A magnetorheological sample environment is presented that allows for in situ magnetic field and shear flow during small-angle neutron scattering (SANS) measurements and is now available at the Institut ... [more ▼]

A magnetorheological sample environment is presented that allows for in situ magnetic field and shear flow during small-angle neutron scattering (SANS) measurements and is now available at the Institut Laue-Langevin (ILL). The setup allows performing simultaneous magnetorheological measurements together with the investigation of structural and magnetic changes on the nanometer length scale underlying the rheological response of ferrofluids. We describe the setup consisting of a commercial rheometer and a custom-made set of Helmholtz coils and show exemplarily data on the field and shear flow alignment of a dispersion of hematite nanospindles in water. [less ▲]

Stochastic and Quantum Thermodynamics of Driven RLC Networks

in Phys. Rev. X (2020), 10(3), 031005

PositionPeak: Stimulating position changes during meetings

in Proceedings of Conference on Human Factors in Computing Systems (2020)

In office environments, workers spend the majority of their workday sitting in a static position behind a desk or around a meeting table. Prolonged sitting time and sedentary behavior have severe negative ... [more ▼]

In office environments, workers spend the majority of their workday sitting in a static position behind a desk or around a meeting table. Prolonged sitting time and sedentary behavior have severe negative health effects. Through this explorative study, we studied how different postures can be stimulated during meetings. We designed PositionPeak: three pieces of furniture aimed at composing a 'dynamic meeting room', subtly encouraging participants to avoid static postures. We video-recorded 5 meetings (N=16) and coded the number of position changes per participant. Participants also filled out a pre- and post-questionnaire about their experience. Our findings show that PositionPeak triggers people to adopt a variety of postures. Participants on average experienced a more efficient meeting but reported physical discomfort with some objects. We discuss the influence of PositionPeak on the meetings' social dynamics, the acceptance of new conventions and design recommendations for new meeting facilities. © 2020 Owner/Author. [less ▲]

Sidelobe Performance Analysis of Noise Waveforms Considering the Doppler Mismatch

in Proceedings of the 21st International Radar Symposium (IRS), Warsaw, Poland, 2020 (2020)

Waveform design and optimization algorithms generally assume a zero-Doppler ideal case to reach an optimum or satisfactory solution in terms of the matched filter output. Therefore, its performance is ... [more ▼]

Waveform design and optimization algorithms generally assume a zero-Doppler ideal case to reach an optimum or satisfactory solution in terms of the matched filter output. Therefore, its performance is usually characterized only in terms of the resultant waveforms autocorrelation function, neglecting the practical situation in which the received signal is modulated by the target’s Doppler shift. Within this context, this work investigates the Doppler mismatch effects in the Integrated Sidelobe Level (ISL) performance of previously designed/optimized noise waveforms. The analysis has shown that, despite much better results for steady targets, the increasing Doppler mismatch reduces the ISL performance of optimized waveforms, until similar levels achieved when no optimization is performed. To address that, a subpulse Doppler processing approach is also considered, and the results have shown that, besides increasing the Doppler tolerance, it has also increased the optimized waveform robustness to the Doppler mismatch, reducing the resultant ISL loss and thus extending its applicability. [less ▲]

Bordertextures – vers une approche transdisciplinaire des frontières. Un rapport d’atelier

in Hamez, Grégory; Defays, Jean-Marc (Eds.) Réalités, perceptions et représentations des frontières. L’espace transfrontalier de la Grande Région Sarre-Lor-Lux (2020)

La présente contribution est conçue sous forme d'un rapport d'atelier et donne un premier aperçu concernant le développement d'une approche des phénomènes de frontières et d'espaces frontaliers sur la ... [more ▼]

La présente contribution est conçue sous forme d'un rapport d'atelier et donne un premier aperçu concernant le développement d'une approche des phénomènes de frontières et d'espaces frontaliers sur la base des études culturelles. Cette approche tente d'être plus large que celle correspondant aux perspectives jusqu'à présent préconisées par les sciences sociales et appréhende les phénomènes des frontières et des espaces frontaliers en tant qu'entités composées de différentes pratiques et différents discours faisant référence aux frontières et aux différences. Ces entités comprises au sens de bordertextures sont exemplairement illustrées à travers des phénomènes concernant la frontière entre les États-Unis et le Mexique, la frontière franco-allemande et l'Irlande du Nord et elles sont déclinées en différentes dimensions d'analyse. Parmi ces dernières, la corporéalité, la spatialité et la matérialité figurent parmi les approches heuristiques des bordertextures que la présente contribution aborde à titre d'exemples. L'approche relativise la perspective largement répandue correspondant à une conception territoriale de la frontière pour élargir la palette des perspectives analytiques et celles des domaines analysés au sein des Border Studies. [less ▲]

Die Siegfried-Figur der Nibelungenüberlieferung in interkultureller Perspektive

in Cornejo, Renata; Schiewer, Gesine Lenore; Weinberg, Manfred (Eds.) Konzepte der Interkulturalität in der Germanistik weltweit (2020)

Siegfried, the hero of the Middle High German »Nibelungenlied«, is not only interesting as a figure from the perspective of a German-national myth formation. This article aims to show that Siegfried is ... [more ▼]

Siegfried, the hero of the Middle High German »Nibelungenlied«, is not only interesting as a figure from the perspective of a German-national myth formation. This article aims to show that Siegfried is also important from the perspective of ›intercultural medieval studies‹. Therefore, the Siegfried figure in the Nibelungenlied is determined by cultural hybridity. His Scandinavian counterpart, Sigurd, is no less revealing as a cultural mediator. [less ▲]

Topological network measures for drug repositioning.

in Briefings in bioinformatics (2020)

Drug repositioning has received increased attention since the past decade as several blockbuster drugs have come out of repositioning. Computational approaches are significantly contributing to these ... [more ▼]

Drug repositioning has received increased attention since the past decade as several blockbuster drugs have come out of repositioning. Computational approaches are significantly contributing to these efforts, of which, network-based methods play a key role. Various structural (topological) network measures have thereby contributed to uncovering unintuitive functional relationships and repositioning candidates in drug-disease and other networks. This review gives a broad overview of the topic, and offers perspectives on the application of topological measures for network analysis. It also discusses unexplored measures, and draws attention to a wider scope of application efforts, especially in drug repositioning. [less ▲]

„Dann eben in die Natur damit“ – Der neue Trend der Waldbestattung in Luxemburg: Geschichte, Beweggründe und ökologische Auswirkungen

in Thiltges, Sébastian; Solte-Gresser, Christiane (Eds.) Kulturökologie und ökologische Kulturen in der Großregion / Écologie culturelle et cultures écologiques dans la Grande Région (2020)

For the environment, humans and their way of life have become one of the most decisive factors of influence: their impact defines the geochronological era of the Anthropocene. These manmade changes ... [more ▼]

For the environment, humans and their way of life have become one of the most decisive factors of influence: their impact defines the geochronological era of the Anthropocene. These manmade changes include one specific type of sediments, namely that of human remains. In industrialized regions, the biologically degradable, organic matter of the human body is often altered by medical implants and pharmaceutical residues. Sepulchral practices may add other toxic substances. This article examines how the recent trend towards woodland burials of cremated remains in Luxembourg is embedded in ecological discourse and imagination, and asks whether it does provide an environment-friendly alternative to traditional full-body inhumations. [less ▲]

Comparative transcriptome analysis of Parkinson’s disease and Hutchinson-Gilford progeria syndrome reveals shared susceptible cellular network processes

in BMC Medical Genomics (2020), 13(114),

Background Parkinson’s Disease (PD) and Hutchinson-Gilford Progeria Syndrome (HGPS) are two heterogeneous disorders, which both display molecular and clinical alterations associated with the aging process ... [more ▼]

Background Parkinson’s Disease (PD) and Hutchinson-Gilford Progeria Syndrome (HGPS) are two heterogeneous disorders, which both display molecular and clinical alterations associated with the aging process. However, similarities and differences between molecular changes in these two disorders have not yet been investigated systematically at the level of individual biomolecules and shared molecular network alterations. Methods Here, we perform a comparative meta-analysis and network analysis of human transcriptomics data from case-control studies for both diseases to investigate common susceptibility genes and sub-networks in PD and HGPS. Alzheimer’s disease (AD) and primary melanoma (PM) were included as controls to confirm that the identified overlapping susceptibility genes for PD and HGPS are non-generic. Results We find statistically significant, overlapping genes and cellular processes with significant alterations in both diseases. Interestingly, the majority of these shared affected genes display changes with opposite directionality, indicating that shared susceptible cellular processes undergo different mechanistic changes in PD and HGPS. A complementary regulatory network analysis also reveals that the altered genes in PD and HGPS both contain targets controlled by the upstream regulator CDC5L. Conclusions Overall, our analyses reveal a significant overlap of affected cellular processes and molecular sub-networks in PD and HGPS, including changes in aging-related processes that may reflect key susceptibility factors associated with age-related risk for PD. [less ▲]