References of "2018"
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See detailAuf dem Weg zur mehrsprachigen Bildung in der frühen Kindheit
Kirsch, Claudine UL

in Universität Luxembourg (Ed.) Bildungsbericht.Bildungsverläufe und Bildungserfolge (2018)

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See detailWealth inequality, frailty, and memory impairment: Is wealthier = healthier true at all older ages?
Leist, Anja UL

Scientific Conference (2018, December)

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See detailSchulische Kompetenzen von Erstklässlern und ihre Entwicklung nach zwei Jahren.
Hoffmann, Danielle UL; Hornung, Caroline UL; Gamo, Sylvie UL et al

Report (2018)

Dieses Kapitel stellt die Befunde aus drei Datenerhebungen (2014, 2015, 2016) der ÉpStan im Zyklus 2.1 vor und zeigt welche schulischen Kompetenzen Erstklässler am Anfang ihrer Schullaufbahn aufweisen und ... [more ▼]

Dieses Kapitel stellt die Befunde aus drei Datenerhebungen (2014, 2015, 2016) der ÉpStan im Zyklus 2.1 vor und zeigt welche schulischen Kompetenzen Erstklässler am Anfang ihrer Schullaufbahn aufweisen und wie sich diese über zwei Jahre hinweg entwickeln. Allgemein betrachtet, sind die für den Zyklus 1 festgehaltenen Bildungsstandards in den drei überprüften Kernkompetenzen („Luxemburgisch-Hörverstehen“, „Vorläuferfertigkeiten der Schriftsprache“ und „Mathematik“) erfüllt. In allen drei Kompetenzen erreicht die Mehrheit der Schülerinnen und Schüler zu Beginn des Zyklus 2.1 das Niveau Avancé. Zwei Jahre später, im Zyklus 3.1, fällt die Verteilung der Schülerinnen und Schüler auf die verschiedenen Kompetenzränge negativer aus als im Zyklus 2.1. Hier haben vergleichsweise mehr Kinder das Niveau Socle in allen drei Kernkompetenzen noch nicht erreicht. Unsere Befunde zeigen außerdem, dass verschiedene außerschulische Faktoren (wie z. B. sozioökonomische Situation, Sprachhintergrund) bereits sehr früh im Verlauf der Schullaufbahn einen äußerst starken Einfluss auf die Testergebnisse haben und dass sich dieser Einfluss über die Jahre hinweg verstärkt. [less ▲]

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See detailPower and Load Optimization in Interference-Coupled Non-Orthogonal Multiple Access Networks
Lei, Lei UL; You, Lei; Yang, Yang UL et al

in IEEE Global Communications Conference (GLOBECOM) 2018 (2018, December)

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See detailLa fiducie et la structuration des fonds d'investissement de droit français
Riassetto, Isabelle UL; Storck, Michel

in Mélanges en l'honneur du professeur Claude Witz (2018)

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See detailLa sémiotique visuelle naissante : Greimas et sa postérité
Colas-Blaise, Marion UL

in La Part de l'Oeil (2018), (32), 275-295

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See detailL’efficacité du retour dans les États membres de l’UE: défis et bonnes pratiques dans l’application des règles européennes en matière de retour
Petry, David UL; Sommarribas, Adolfo UL; Coda, Nicolas UL et al

Article for general public (2018)

Le retour des ressortissants de pays tiers en séjour irrégulier est l‘un des principaux piliers de la politique de l‘UE en matière de migration et d‘asile. Dans son plan d‘action sur le retour en 2015 et ... [more ▼]

Le retour des ressortissants de pays tiers en séjour irrégulier est l‘un des principaux piliers de la politique de l‘UE en matière de migration et d‘asile. Dans son plan d‘action sur le retour en 2015 et dans sa communication de 2017 relative à une politique de retour plus efficace et la recommandation qui l‘a accompagnée, la Commission a souligné la nécessité d‘une mise en œuvre plus stricte des règles européennes en la matière. Cette note de synthèse présente les principaux résultats de l’étude réalisée en 2017 par le point de contact de l´European Migration Network au Luxembourg intitulée «L’efficacité du retour dans les Etats membres de l’UE: défis et bonnes pratiques dans l’application des règles européennes en matière de retour» ainsi que du rapport synthétique qui en résulte. L’étude se base sur les informations recueillies jusqu’au mois de juillet 2017. Cette note de synthèse vise à analyser l‘impact des règles européennes sur le retour ainsi que sur les politiques et pratiques mises en œuvre dans les différents États membres. Elle présente également la manière dont les normes et procédures européennes ont été interprétées et appliquées au niveau national et, dans la mesure du possible, leur impact sur l‘efficacité du dispositif de retour. Toutefois, une certaine prudence s’impose tant il est difficile d‘établir des liens de causalité entre des mesures politiques spécifiques et le nombre de retours mis en œuvre. [less ▲]

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See detailFriend or Foe? Portraying the German Occupier in Luxembourg (1914-1918).
Camarda, Sandra UL

in Mutations. Mémoires et Perspectives du Bassin Minier (2018), (10), 161-167

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See detailSuccessive convex approximation algorithms for sparse signal estimation with nonconvex regularizations
Yang, Yang UL; Pesavento, Marius; Chatzinotas, Symeon UL et al

in IEEE Journal of Selected Topics in Signal Processing (2018), 12(6), 1286-1302

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See detailEn construction. La fabrique française d'Internet et du Web dans les années 1990
Schafer, Valerie UL

Book published by INA Editions (2018)

Cet ouvrage s’inscrit dans le cadre d’une histoire jeune et très contemporaine, celle d’Internet, du Web et des cultures numériques et explore leur fabrique dans les années 1990 en France. Cette recherche ... [more ▼]

Cet ouvrage s’inscrit dans le cadre d’une histoire jeune et très contemporaine, celle d’Internet, du Web et des cultures numériques et explore leur fabrique dans les années 1990 en France. Cette recherche, à la croisée de l’histoire des médias, de l’histoire de l’innovation, et de l’histoire sociale et culturelle, reflète les apports d’une approche française de l’histoire d’Internet et du Web. Matérialité et infrastructures, temporalités et trajectoires, espaces et territoires traversent les cinq chapitres du livre. Ils apportent des arguments au choix d’une analyse nationale d’un phénomène pourtant transnational, en s’intéressant à l’attribution des noms de domaine et à la francophonie au sein de la Toile, à la transition entre la culture Minitel et celle du Web, ou encore à la place d’un État qui passe du volontarisme et du monopole des télécommunications à la dérégulation et aux imaginaires des autoroutes puis de la société de l’information. Explorant les pratiques, difficultés, tâtonnements de la période et le tournant grand public du Web, on croise au cours de cette navigation des informaticiens, des entrepreneurs, des politiques, des passionnés de science-fiction, des militants, autant d’acteurs qui se confrontent, débattent, co-construisent. Ils vous invitent à les suivre dans un chantier entre « cathédrale et bazar », pour reprendre Eric Raymond, dont l’exotisme mais aussi l’actualité des débats ne cessent de nous frapper. Bienvenue dans le Cyberespace des années 1990 ! [less ▲]

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See detailFrench memories about the ARPANET: a conversation with Michel Élie and Gérard Le Lann
Schafer, Valerie UL; Paloque-Bergès, Camille

in Internet Histories: Digital Technology, Culture and Society (2018)

Although the ARPANET was a United States-funded project that was deeply rooted in US post-war science and technology policies, it had an international dimension from its very early days. The memories of ... [more ▼]

Although the ARPANET was a United States-funded project that was deeply rooted in US post-war science and technology policies, it had an international dimension from its very early days. The memories of Michel Elie and Gerard Le Lann are oriented towards their US experience. They testify to an early French presence in the ARPANET project at two stages of its history: in 1969–1970, when the first nodes came into activity, and in 1973–1974, when TCP, which evolved into TCP/IP and became the Internet’s flagship protocol, was defined, replacing NCP, which was at the heart of the ARPANET. They thus highlight crucial but different sides of the ARPANET’s genesis. [less ▲]

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See detailGenotype-phenotype relations for the Parkinson’s disease genes SNCA, LRRK2, VPS35: MDSGene Review.
Trinh, Joanne; Zeldenrust, Florentine M. J.; Huang, Jana et al

in Movement Disorders (2018), 33(12), 1857-1870

This comprehensive MDSGene review is devoted to the three autosomal-dominant PD forms: PARK-SNCA, PARK-LRRK2, and PARK-VPS35. It follows MDSGene's standardized data extraction protocol, screened a total ... [more ▼]

This comprehensive MDSGene review is devoted to the three autosomal-dominant PD forms: PARK-SNCA, PARK-LRRK2, and PARK-VPS35. It follows MDSGene's standardized data extraction protocol, screened a total of 2,972 citations, and is based on fully curated phenotypic and genotypic data on 937 patients with dominantly inherited PD attributed to 44 different mutations in SNCA, LRRK2, or VPS35. All of these data are also available in an easily searchable online database (www.mdsgene.org), which additionally provides descriptive summary statistics on phenotypic and genetic data. Despite the high degree of missingness of phenotypic features and unsystematic reporting of genotype data in the original literature, the present review recapitulates many of the previously described findings including later onset of disease (median age at onset: ∼49 years) compared to recessive forms of PD of an overall excellent treatment response. Our systematic review validates previous reports showing that SNCA mutation carriers have a younger age at onset compared to LRRK2 and VPS35 (P < 0.001). SNCA mutation carriers often have additional psychiatric symptoms, and although not exclusive to only LRRK2 or VPS35 mutation carriers, LRRK2 mutation carriers have a typical form of PD, and, lastly, VPS35 mutation carriers have good response to l-dopa. [less ▲]

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See detailWeb History in Context
Schafer, Valerie UL; Thierry, Benjamin

in Brügger, Niels; Milligan, Ian (Eds.) The SAGE Handbook of Web History FIRST EDITION (2018)

The presence now of the Web in every area of life demands studies which constitute it simultaneously both as itself a contextualising object and as anchored in a context. Contextualising because today it ... [more ▼]

The presence now of the Web in every area of life demands studies which constitute it simultaneously both as itself a contextualising object and as anchored in a context. Contextualising because today it directly influences an infinite number of objects, which can no longer be studied without taking account of their echoes online. In transmedia dynamics in particular, we can see how the Web is increasingly becoming an ever-present backdrop to controversies, to the configuration of information and even to interpersonal relationships. Equally, the Web must find its own contextualisation, first of all – since we are historians – from a diachronic perspective. The first challenge is not to remain within the limits set by the technology itself. This twofold approach (the Web in context and the Web as context) suggests how focused we need to be on the construction of an ever-changing socio-technical reality – a return to a totalising, process-focused history which takes account of ongoing developments. We should resist the effects of any discourse tending to fix realities or establish, in hieratic or metonymic fashion, an image of ‘THE’ Web. The present analysis falls into three main sections, which interrogate, in turn, the diachronic or temporal contextualisation, the boundaries or spatial contextualisation, and finally collective and individual experiences of the Web. [less ▲]

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See detailHydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release
Mazumder, A; Lee, JY; Talhi, O et al

in Cancer Letters (2018)

We synthetized and investigated the anti-leukemic potential of the novel cytostatic bis(4-hydroxycoumarin) derivative OT-55 which complied with the Lipinski's rule of 5 and induced differential toxicity ... [more ▼]

We synthetized and investigated the anti-leukemic potential of the novel cytostatic bis(4-hydroxycoumarin) derivative OT-55 which complied with the Lipinski's rule of 5 and induced differential toxicity in various chronic myeloid leukemia (CML) cell models. OT-55 triggered ER stress leading to canonical, caspase-dependent apoptosis and release of danger associated molecular patterns. Consequently, OT-55 promoted phagocytosis of OT-55-treated CML cells by both murine and human monocyte-derived macrophages. Moreover, OT-55 inhibited tumor necrosis factor α-induced activation of nuclear factor-кB and produced synergistic effects when used in combination with imatinib to inhibit colony formation in vitro and Bcr-Abl+ patient blast xenograft growth in zebrafish. Furthermore, OT-55 synergized with omacetaxine in imatinib-resistant KBM-5 R cells to inhibit the expression of Mcl-1, triggering apoptosis. In imatinib-resistant K562 R cells, OT-55 triggered necrosis and blocked tumor formation in zebrafish in combination with omacetaxine. [less ▲]

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See detailGood Business: The Economic Case for Protecting Human Rights
Baglayan, Basak UL; Landau, Ingrid; Mcvey, Marisa et al

Report (2018)

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See detailLiterary Histories, National Literatures, and Early Conceptions of World Literature in the Athenaeum, 1833-1838.
Millim, Anne-Marie UL

in Yearbook of English Studies (2018), 48

The reign of William IV represents a period concerned with questions of national identity, not only in a national context, but also in a global one. Periodicals of the time, such as the Athenaeum, present ... [more ▼]

The reign of William IV represents a period concerned with questions of national identity, not only in a national context, but also in a global one. Periodicals of the time, such as the Athenaeum, present the co-existence of two related, but inherently opposite conceptions of literature and its functions: Goethe’s idea of Weltliteratur is contemporaneous to developments in the formation and consolidation of national literatures, which can be observed to co-exist even in the early nineteenth-century. World literature, as imagined by Goethe in the 1930s, represents a way of circumventing the inward-looking attitude of nationalism, and of prioritising fluidity and flexibility over stability. National literature, as practiced widely during the nineteenth century, represents a way of grounding national genius in literary texts, either by scrutinising only the works of authors of a specific nationality, or by comparing them in a transnational, intercultural perspective. This article investigates two series of articles published almost concurrently in the Athenaeum: ‘A Biographical and Critical History of the Literature of the last Fifty Years’, by Allan Cunningham in 1833, and ‘Literature of the Nineteenth Century’, by diverse authors between 1834 and 1838. This article highlights the co-existence between different authorial focalisations in historicising and historiographing literature, demonstrating the malleability, undecidability, and arbitrariness of dominant models of national literary identities. I argue that during the 1830s, the Athenaeum’s outlook is decidedly cosmopolitan and international as the contributors engage with European literature equally often as they do with British texts. They are also eager to stretch the readers’ awareness beyond the European context, embracing the wealth of ideas, styles, and perspectives as culturally enriching, but not exotic, erudition. [less ▲]

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See detailScience and Technology Studies Approaches to Web History
Musiani, Francesca; Schafer, Valerie UL

in Brügger, Niels; Milligan, Ian (Eds.) The SAGE Handbook of Web History FIRST EDITION (2018)

This chapter seeks to show the value of a relational, practice-oriented approach – what in STS vocabulary is called ‘unpacking black boxes’, or doing a sociology ‘of assemblages’. The chapter examines how ... [more ▼]

This chapter seeks to show the value of a relational, practice-oriented approach – what in STS vocabulary is called ‘unpacking black boxes’, or doing a sociology ‘of assemblages’. The chapter examines how this approach can shed light on the hybrid mobilizations of innovators, consumers, users and entrepreneurs – alongside their creations and cultures – that have made the Web the complex socio-technical system it is today. [less ▲]

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See detailRecent Advances on GNSS Multipath Reflectometry (GNSS-MR) for Sea and Lake Level Studies
van Dam, Tonie UL; Tabibi, Sajad UL; Geremia-Nievinski, F. et al

Scientific Conference (2018, December)

Global navigation satellite system multipath reflectometry (GNSS-MR) has been used to exploit signals of opportunity at L-band for ground-based sea and lake level studies at several locations in the last ... [more ▼]

Global navigation satellite system multipath reflectometry (GNSS-MR) has been used to exploit signals of opportunity at L-band for ground-based sea and lake level studies at several locations in the last few years. Although geodetic-quality antennas are designed to boost the direct transmission from the satellite and to suppress indirect surface reflections, the delay of reflections with respect to the line-of-sight propagation can be used to estimate the water-surface level in a stable terrestrial reference frame. In this contribution, signal-to-noise ratio (SNR) observations from commercial off-the-shelf systems are used to retrieve water level at multiple constellations and modulations. We constrained phase-shifts so as yield more precise reflector heights and further corrected for the tropospheric propagation delays for greater accuracy. We assess GNSS-MR accuracy and precision in two cases. In the first one, using the inversion formal uncertainty and modulation-specific variance factors, reflector heights are combined and converted to water level at hourly epoch spacing and eight-hourly averaging window length. The RMSE between GNSS-MR and tide gauge (TG) records for a single station in the Great Lakes is 1.93 cm for a 12-year period. In the second case, we employ an extended dynamic model, taking tidal velocity and acceleration into account, which is applied for ten stations worldwide. Regression slope between GNSS-MR and TG exhibits a smaller deviation from the ideal 1:1 relationship, compared to the conventional dynamic model (with no acceleration). The RMSE between sub-hourly GNSS-MR and TG is 1.98 cm, with 0.998 correlation coefficient. Tidal constituents agree at the sub-mm level between GNSS-MR and TG. [less ▲]

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