AIFMD vs. the Regulation on European Long-Term Investment Funds (ELTIFR)

in Zetzsche, Dirk Andreas (Ed.) The AIFM Directive (2015)

Risk Management

in Zetzsche, Dirk Andreas (Ed.) The AIFM Directive (2015)

Investor Information, Disclosure and Transparency

in Zetzsche, Dirk Andreas (Ed.) The AIFM Directive (2015)

Kreditfonds zwischen Anleger- und Systemschutz

in Recht der Finanzinstrumente (2015)

Appointment, Authorization and Organization of the AIFM

in Zetzsche, Dirk Andreas (Ed.) The AIFM Directive (2015)

Evaluation of an anatomically augmented Statistical Shape Model of the scapula: Clinical validation and reliability of landmark selection. Submited to

in Computer Methods in Biomechanics and Biomedical Engineering. Imaging and Visualization (2015)

Use of a Computed Tomography Based Approach to Validate Noninvasive Devices to Measure Rotational Knee Laxity

in International Scholarly Research Notices (2015)

The purpose of this study is to validate a noninvasive rotational knee laxity measuring device called “Rotameter P2” with an approach based on Computed Tomography (CT). This CT-approach using X-rays is ... [more ▼]

The purpose of this study is to validate a noninvasive rotational knee laxity measuring device called “Rotameter P2” with an approach based on Computed Tomography (CT). This CT-approach using X-rays is hence invasive and can be regarded as a precise reference method that may also be applied to similar devices. An error due to imperfect femur fixation was observed but can be neglected for small torques. The most significant estimation error is due to the unavoidable soft tissues rotation and hence flexibility in the measurement chain. The error increases with the applied torque.The assessment showed that the rotational knee angle measured with the Rotameter is still overestimated because of thigh and femur displacement, soft tissues deformation, and measurement artefacts adding up to a maximum of 285% error at +15Nm for the Internal Rotation of female volunteers. This may be questioned if such noninvasive devices for measuring the Tibia-Femoral Rotation (TFR) can help diagnosing knee pathologies and investigate ligament reconstructive surgery. [less ▲]

Analysis of the Authenticated Cipher MORUS (v1)

in Cryptography and Information Security in the Balkans: First International Conference, BalkanCryptSec 2015 (2015)

We present several new observations on the CAESAR candidate MORUS (v1). First, we report a collision on its StateUpdate(S, M ) function. Second, we describe a distinguisher in a nonce-reuse scenario with ... [more ▼]

We present several new observations on the CAESAR candidate MORUS (v1). First, we report a collision on its StateUpdate(S, M ) function. Second, we describe a distinguisher in a nonce-reuse scenario with probability 1. Finally, we observe that the differences in some words of the state after the initialization have probabilities significantly higher than the random case. We note that the presented results do not threaten the security of the scheme. This is the first external analysis of the authenticated cipher MORUS. [less ▲]

The Dutch Parliament and EU Affairs: Decentralizing Scrutiny

in Hefftler, Claudia; Neuhold, Christine; Rozenberg, Olivier (Eds.) et al The Palgrave Handbook of National Parliaments and the European Union (2015)

Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond.

in Briefings in bioinformatics (2015)

Genome-scale metabolic network reconstructions provide a basis for the investigation of the metabolic properties of an organism. There are reconstructions available for multiple organisms, from ... [more ▼]

Genome-scale metabolic network reconstructions provide a basis for the investigation of the metabolic properties of an organism. There are reconstructions available for multiple organisms, from prokaryotes to higher organisms and methods for the analysis of a reconstruction. One example is the use of flux balance analysis to improve the yields of a target chemical, which has been applied successfully. However, comparison of results between existing reconstructions and models presents a challenge because of the heterogeneity of the available reconstructions, for example, of standards for presenting gene-protein-reaction associations, nomenclature of metabolites and reactions or selection of protonation states. The lack of comparability for gene identifiers or model-specific reactions without annotated evidence often leads to the creation of a new model from scratch, as data cannot be properly matched otherwise. In this contribution, we propose to improve the predictive power of metabolic models by switching from gene-protein-reaction associations to transcript-isoform-reaction associations, thus taking advantage of the improvement of precision in gene expression measurements. To achieve this precision, we discuss available databases that can be used to retrieve this type of information and point at issues that can arise from their neglect. Further, we stress issues that arise from non-standardized building pipelines, like inconsistencies in protonation states. In addition, problems arising from the use of non-specific cofactors, e.g. artificial futile cycles, are discussed, and finally efforts of the metabolic modelling community to unify model reconstructions are highlighted. [less ▲]