First International Workshop on Bidirectional Transformations (BX 2012): Preface

in Electronic Communications of the EASST (2012), 49

Bidirectional transformations (bx) are a mechanism for maintaining the consistency of two (or perhaps more) related sources of information. Such sources can be databases, software models, documents, or ... [more ▼]

Bidirectional transformations (bx) are a mechanism for maintaining the consistency of two (or perhaps more) related sources of information. Such sources can be databases, software models, documents, or their abstract models like graphs or trees. BX are an emerging topic in a wide range of research areas with prominent presence at top conferences in different fields. The methodologies used for bx range from classical program transformation to graph transformation techniques, from ad-hoc techniques for data synchronization to the development of domain-specific languages and their integration. The First International Workshop on Bidirectional Transformations (BX 2012) established a dedicated venue for bx in all relevant areas. It was initiated by the participants of the Dagstuhl Seminar "Bidirectional Transformations" (bx) in Germany 2011, which continued the GRACE International Meeting on Bidirectional Transformations held in Japan 2008. The workshop BX 2012 took place at the Tallinn University of Technology, Estonia on the 25th of March 2012, as a satellite event of ETAPS 2012, the European Joint Conferences on Theory and Practice of Software. [less ▲]

Bildungsbeteiligung und soziale Partizipation von Migrantinnen und Migranten - Erkenntnisse einer Vollerhebung unter den Stipendiatinnen und Stipendiaten der Hans-Böckler-Stiftung

in Soziale Ungleichheit in der Einwanderungsgesellschaft. Kategorien, Konzepte, Einflussfaktoren (2012)

Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).

in Analytical and Bioanalytical Chemistry (2012), 402(3), 1183-98

Here we present an ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for extracellular measurements of known and unexpected metabolites in parallel. The method was developed by ... [more ▼]

Here we present an ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method for extracellular measurements of known and unexpected metabolites in parallel. The method was developed by testing 86 metabolites, including amino acids, organic acids, sugars, purines, pyrimidines, vitamins, and nucleosides, that can be resolved by combining chromatographic and m/z dimensions. Subsequently, a targeted quantitative method was developed for 80 metabolites. The presented method combines a UPLC approach using hydrophilic interaction liquid chromatography (HILIC) and MS detection achieved by a hybrid quadrupole-time of flight (Q-ToF) mass spectrometer. The optimal setup was achieved by evaluating reproducibility and repeatability of the analytical platforms using pooled quality control samples to minimize the drift in instrumental performance over time. Then, the method was validated by analyzing extracellular metabolites from acute lymphoblastic leukemia cell lines (MOLT-4 and CCRF-CEM) treated with direct (A-769662) and indirect (AICAR) AMP activated kinase (AMPK) activators, monitoring uptake and secretion of the targeted compound over time. This analysis pointed towards a perturbed purine and pyrimidine catabolism upon AICAR treatment. Our data suggest that the method presented can be used for qualitative and quantitative analysis of extracellular metabolites and it is suitable for routine applications such as in vitro drug screening. [less ▲]

Neue Attraktivität, und wenn ja wieviele? Von Reurbanisierungs-Diskursen, Bewertungsfragen und den Chancen einer stärkeren Interaktion von Forschung und Praxis

in Adam, Brigitte; Sturm, Gabriele (Eds.) Die Attraktivität großer Städte – ökonomisch, demografisch, kulturell (2012)

Zwischen "Kartoffelbäuerin" und "Golftussi". Schönheitshandeln im sozialen und biographischen Kontext.

in Filter, Dagmar; Reich, Jana (Eds.) "Bei mir bist du schön..." Kritische Reflexionen über Konzepte von Schönheit und Körperlichkeit. (2012)

Remembering World War II and legitimating Luxembourgish as the national language: consensus or conflict?

in Langer, Nils; Davies, Steffan; Wandenbussche, Wim (Eds.) Language and History, Linguistics and Historiography (2012)

Private Schriftlichkeit:Sprachwahl und Verschriftlichungsstrategien in Feldpostbriefen des 2. Weltkriegs

in Grucza, Franciszek; Zhu, Jianhua (Eds.) Akten des XII. Internationalen Germanistenkongresses (2012)

An iterative economic residential choice ABM of urban growth in Luxembourg (extended abstract)

in Pinto N (Ed.) Proceedings of the Symposium on Cellular Automata Models of Urban and Spatial Systems (2012)

Developing a fast photochemical calculator for an integrated assessment model

in International Journal of Environment and Pollution (2012)

The use of integrated assessment models, in air quality policy, which combines atmospheric models with others from different fields, raises the need of developing specific air quality modelling concepts ... [more ▼]

The use of integrated assessment models, in air quality policy, which combines atmospheric models with others from different fields, raises the need of developing specific air quality modelling concepts. The air quality model, AUSTAL2000-AYLTP uses an adapted version of AUSTAL2000 model to calculate transport coupled with a fast photochemical module. Two approaches are compared: one using a look-up table and the other using a coupled box model. The lookup table has been built using the OZIPR model by simulating a large set of possible combinations of meteorological variables and precursor concentrations. The second approach consists of coupling the Lagrangian model AUSTAL2000 with the OZIPR box model. In both approaches the photochemistry is included in the mode by using a quasi-linear reaction rates coefficient which is used to affect the mass of the Lagrangian particles. We discuss the differences and the suitability of the two model versions, through exploring CPU time flexibility, applicability and accuracy. [less ▲]

Macbeth and the joystick: Evidence for moral cleansing after playing a violent video game

in Journal of Experimental Social Psychology (2012), 48