References of "2009"
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See detailLuxemburg, Metz und das Reich. Die Reichsstadt Metz im Gesichtsfeld Karls IV.
Margue, Michel UL

in Die Goldene Bulle. Politik - Wahrnehmung - Rezeption (2009)

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See detailA symplectic map between hyperbolic and complex Teichmüller theory
Krasnov, Kirill; Schlenker, Jean-Marc UL

in Duke Mathematical Journal (2009), 150(2), 331--356

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See detailSpace and time resolving molecular acoustics as a tool to visualize epoxy formation at a planar hardener-resin interface
Sanctuary, Roland UL; Philipp, Martine UL; Müller, Ulrich UL et al

in Chemical Physics Letters (2009), 476(1-3), 11-14

Scanning Brillouin microscopy visualizes the temporal evolution of a heterogeneous hypersonic profile during chemical reactions and transport processes around a planar phase boundary between an epoxy ... [more ▼]

Scanning Brillouin microscopy visualizes the temporal evolution of a heterogeneous hypersonic profile during chemical reactions and transport processes around a planar phase boundary between an epoxy resin and hardener. The hypersonic investigations are interpreted in terms of structural formation and annihilation in the layered sample and are compared to results obtained for a well mixed bulk sample of the same composition of reactants. Chaotic transport channels are made responsible for the creation of local glassy heterogeneities not observable in the bulk material on a macroscopic level. [less ▲]

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See detailAssociations between demanding occupational conditions and tobacco, alcohol and cannabis use among French working men and women.
Legleye, Stéphane; Peretti-Watel, P.; Baumann, Michèle UL

in International Institute, of Sociology (Ed.) 39th World Congress of the International Institute of Sociology (2009)

This study assessed associations between demanding workplace conditions and substance use in France, taking account of gender. A total of 13,241 workers were randomly selected and interviewed by telephone ... [more ▼]

This study assessed associations between demanding workplace conditions and substance use in France, taking account of gender. A total of 13,241 workers were randomly selected and interviewed by telephone to obtain information about: alcohol use, tobacco use, cannabis use, socio-demographic characteristics, occupation, type of work contract, and working conditions (physical and mental demands, time pressure, lack of rest, satisfaction with conditions, opportunity to learn new things). Data were analyzed using multivariate logistic models. Alcohol abuse was reported by 20% of men and 11% of women; 32% and 24%, respectively, used tobacco every day; and 9% and 3% had used cannabis in the previous 12 months (p<0.001). Among men, tobacco use related to physical and mental demands, dissatisfaction with work and not learning new things (increased risk IR 22-31%). Among women, it related to physical demand, time pressure, lack of rest and not learning new things (IR 15-43%). Alcohol abuse related to dissatisfaction with work among men (IR 22%). Cannabis use related to dissatisfaction with work in men (IR 93%). Having a short-term contract related to all three substances uses among men (IR 25-57%) and to alcohol abuse and tobacco use among women (IR 21-35%). Being freelance related to use of tobacco and cannabis use among men (IR 50-89%). In conclusion, alcohol, tobacco and cannabis use were related to demanding occupational conditions, but in different ways among males and females. These findings suggest that improving workplace conditions and limiting short-term and freelance employment may help prevent substance use and related diseases. [less ▲]

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See detailLæring retur
Biesta, Gert UL

Book published by Unge Pædagoger (2009)

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See detailFinite element simulation of metal-semiconductor-metal photodetector
Guarino, G.; Donaldson, W. R.; Mikulics, Martin et al

in Solid-State Electronics (2009), 53(10), 1144-1148

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See detailÄrgerreaktionen in der Mediation
Steffgen, Georges UL

in Perspektive Mediation (2009), 6

Im Kontext eines Mediationsprozesses sind häufig emotionale Reaktionen der Beteiligten festzustellen. Insbesondere Ärgerreaktionen können auftreten und sich sowohl destruktiv als auch konstruktiv auf die ... [more ▼]

Im Kontext eines Mediationsprozesses sind häufig emotionale Reaktionen der Beteiligten festzustellen. Insbesondere Ärgerreaktionen können auftreten und sich sowohl destruktiv als auch konstruktiv auf die Konfliktbearbeitung auswirken. Aufbauend auf einer Analyse der Funktionalität und Internationalität des Ärgers kann eine selbst- oder fremdgerichtete Ärgerregulation indiziert sein. Konkrete Möglichkeiten werden hierzu aufgezeigt. [less ▲]

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See detailAttentional networks are differentially affected by baro-afferent feedback
Schulz, André UL; Wager, J.; Romer, S. et al

in Frontiers in Behavioral Neuroscience (2009)

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See detailStein's method and exact Berry-Esseen asymptotics for functionals of Gaussian fields
Nourdin, Ivan UL; Peccati, Giovanni UL

in Annals of Probability (2009), 37(6), 2231--2261

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See detailMechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach.
Witt, Johannes; Barisic, Sandra; Schumann, Eva et al

in BMC Systems Biology (2009), 3

BACKGROUND: Biological effects of nuclear factor-kappaB (NF kappaB) can differ tremendously depending on the cellular context. For example, NF kappaB induced by interleukin-1 (IL-1) is converted from an ... [more ▼]

BACKGROUND: Biological effects of nuclear factor-kappaB (NF kappaB) can differ tremendously depending on the cellular context. For example, NF kappaB induced by interleukin-1 (IL-1) is converted from an inhibitor of death receptor induced apoptosis into a promoter of ultraviolet-B radiation (UVB)-induced apoptosis. This conversion requires prolonged NF kappaB activation and is facilitated by IL-1 + UVB-induced abrogation of the negative feedback loop for NF kappaB, involving a lack of inhibitor of kappaB (I kappaB alpha) protein reappearance. Permanent activation of the upstream kinase IKK beta results from UVB-induced inhibition of the catalytic subunit of Ser-Thr phosphatase PP2A (PP2Ac), leading to immediate phosphorylation and degradation of newly synthesized I kappaB alpha. RESULTS: To investigate the mechanism underlying the general PP2A-mediated tuning of IKK beta phosphorylation upon IL-1 stimulation, we have developed a strictly reduced mathematical model based on ordinary differential equations which includes the essential processes concerning the IL-1 receptor, IKK beta and PP2A. Combining experimental and modelling approaches we demonstrate that constitutively active, but not post-stimulation activated PP2A, tunes out IKK beta phosphorylation thus allowing for I kappaB alpha resynthesis in response to IL-1. Identifiability analysis and determination of confidence intervals reveal that the model allows reliable predictions regarding the dynamics of PP2A deactivation and IKK beta phosphorylation. Additionally, scenario analysis is used to scrutinize several hypotheses regarding the mode of UVB-induced PP2Ac inhibition. The model suggests that down regulation of PP2Ac activity, which results in prevention of I kappaB alpha reappearance, is not a direct UVB action but requires instrumentality. CONCLUSION: The model developed here can be used as a reliable building block of larger NF kappa B models and offers comprehensive simplification potential for future modeling of NF kappa B signaling. It gives more insight into the newly discovered mechanisms for IKK deactivation and allows for substantiated predictions and investigation of different hypotheses. The evidence of constitutive activity of PP2Ac at the IKK complex provides new insights into the feedback regulation of NF kappa B, which is crucial for the development of new anti-cancer strategies. [less ▲]

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See detailCaring for dependent people. Carers Evaluation scales
Hoffmann, Martine UL; Ferring, Dieter UL

in Final Conference of the CARERS Project, Liaison Office Brussels. Brussels ,Belgium (2009)

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See detailDas mittelalterliche Straßennetz in der Stadt Luxemburg
Pauly, Michel UL

in Der Luxemburg Atlas / Atlas du Luxembourg: Vielfalt und Wandel Luxemburgs im Kartenbild (2009)

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See detailStress Strengthens Memory of first impressions of others’ positive personality traits
Lass-Hennemann, J.; Kuehl, L.; Schulz, André UL et al

in Frontiers in Behavioral Neuroscience (2009)

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See detailGuerres et occupations dans la première moitié du 20ème siècle
Majerus, Benoît UL

in Jeanneney, Jean-Noël (Ed.) 27 leçons d'histoire (2009)

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See detailJohann Heinrich Pestalozzi. Schriften zur Französischen Revolution
Tröhler, Daniel UL

Book published by Pestalozzianum (2009)

Achtbändige Studienausgabe der Werke Johann Heinrich Pestalozzis. In den hier versammelten Schriften zur Französischen Revolution setzt sich Pestalozzi mit den sozialen und wirtschaftlichen Ursachen und ... [more ▼]

Achtbändige Studienausgabe der Werke Johann Heinrich Pestalozzis. In den hier versammelten Schriften zur Französischen Revolution setzt sich Pestalozzi mit den sozialen und wirtschaftlichen Ursachen und Folgen der Französischen Revolution auseinander. Diese Analysen erlauben es ihm, Stellung zu den politischen Unruhen nehmen, die im Gefolge der Französischen Revolution auch auf die Schweiz übergriffen (Stäfner Unruhen 1794/95). Trotz seiner grundsätzlichen Sympathie für die Anliegen der minder berechtigten Landbevölkerung weist er eine Neuorientierung der Gesellschaft zurück, die nur das wirtschaftliche Eigeninteresse der Bürger ins Zentrum rückt und das Gemeinwohl vernachlässigt. [less ▲]

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See detailDer historische Hintergrund von Romfahrt und Bilderchronik
Pauly, Michel UL

in Margue, Michel; Pauly, Michel; Schmid, Wolfgang (Eds.) Der Weg zur Kaiserkrone. Der Romzug Heinrichs VII. in der Darstellung Erzbischof Balduins von Trier (2009)

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See detailJohann Heinrich Pestalozzi. Écrits sur la Méthode, Volume II - Industrie, pauvreté et éducation.
Soëtard, Michel; Tröhler, Daniel UL

Book published by Lep (2009)

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See detailMéthodologie et interdisciplinarité
Kmec, Sonja UL; Majerus, Benoît UL

in Majerus, Benoît; Kmec, Sonja; Margue, Michel (Eds.) et al Dépasser le cadre national des 'lieux de mémoire'. Innovations méthodologiques, approches comparatives, lectures transnationales (2009)

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See detailON/OFF and beyond--a boolean model of apoptosis.
Schlatter, Rebekka; Schmich, Kathrin; Avalos Vizcarra, Ima et al

in PLoS Computational Biology (2009), 5(12), 1000595

Apoptosis is regulated by several signaling pathways which are extensively linked by crosstalks. Boolean or logical modeling has become a promising approach to capture the qualitative behavior of such ... [more ▼]

Apoptosis is regulated by several signaling pathways which are extensively linked by crosstalks. Boolean or logical modeling has become a promising approach to capture the qualitative behavior of such complex networks. Here we built a large-scale literature-based Boolean model of the central intrinsic and extrinsic apoptosis pathways as well as pathways connected with them. The model responds to several external stimuli such as Fas ligand, TNF-alpha, UV-B irradiation, interleukin-1beta and insulin. Timescales and multi-value node logic were used and turned out to be indispensable to reproduce the behavior of the apoptotic network. The coherence of the model was experimentally validated. Thereby an UV-B dose-effect is shown for the first time in mouse hepatocytes. Analysis of the model revealed a tight regulation emerging from high connectivity and spanning crosstalks and a particular importance of feedback loops. An unexpected feedback from Smac release to RIP could further increase complex II formation. The introduced Boolean model provides a comprehensive and coherent description of the apoptosis network behavior. It gives new insights into the complex interplay of pro- and antiapoptotic factors and can be easily expanded to other signaling pathways. [less ▲]

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