References of "2008"
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See detailDie empirische Analyse von Sozialisationsprozessen
Boehnke, Klaus; Hadjar, Andreas UL

in Hurrelmann, Klaus; Grundmann, Matthias; Walper, Sabine (Eds.) Handbuch Sozialisationsforschung, 7 (2008)

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See detailMetabolic networks are NP-hard to reconstruct.
Nikoloski, Zoran; Grimbs, Sergio; May, Patrick UL et al

in Journal of Theoretical Biology (2008), 254(4), 807-16

High-throughput data from various omics and sequencing techniques have rendered the automated metabolic network reconstruction a highly relevant problem. Our approach reflects the inherent probabilistic ... [more ▼]

High-throughput data from various omics and sequencing techniques have rendered the automated metabolic network reconstruction a highly relevant problem. Our approach reflects the inherent probabilistic nature of the steps involved in metabolic network reconstruction. Here, the goal is to arrive at networks which combine probabilistic information with the possibility to obtain a small number of disconnected network constituents by reduction of a given preliminary probabilistic metabolic network. We define automated metabolic network reconstruction as an optimization problem on four-partite graph (nodes representing genes, enzymes, reactions, and metabolites) which integrates: (1) probabilistic information obtained from the existing process for metabolic reconstruction from a given genome, (2) connectedness of the raw metabolic network, and (3) clustering of components in the reconstructed metabolic network. The practical implications of our theoretical analysis refer to the quality of reconstructed metabolic networks and shed light on the problem of finding more efficient and effective methods for automated reconstruction. Our main contributions include: a completeness result for the defined problem, polynomial-time approximation algorithm, and an optimal polynomial-time algorithm for trees. Moreover, we exemplify our approach by the reconstruction of the sucrose biosynthesis pathway in Chlamydomonas reinhardtii. [less ▲]

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See detailQuelle place pour l'école dans la société luxembourgeoise de demain ?
Dierendonck, Christophe UL; Martin, Romain UL; Meyers, Christian UL et al

in Martin, Romain; Dierendonck, Christophe; Meyers, Christian (Eds.) et al La place de l'école dans la société luxembourgeoise de demain (2008)

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See detailCadres de participation en transition: une perspective multimodale sur l'organisation de la parole en classe
Steinbach Kohler, Fee; Fasel Lauzon, Virginie; Berger, Evelyne UL

in Congrès Mondial de Linguistique Française, Paris, France, 2008 (2008)

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See detailElastic Consistency in Decentralized Distributed Virtual Environments
Schloss, Hermann; Botev, Jean UL; Esch, Markus UL et al

in Proceedings of the 4th International Conference on Automated Solutions for Cross Media Content and Multi-channel Distribution (AXMEDIS) (2008)

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See detailCharge and doping distributions by capacitance profiling in Cu(In,Ga)Se2 solar cells
Cwil, Michael; Igalson, Malgorzata; Zabierowski, Powel et al

in Journal of Applied Physics (2008), 103

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See detailProceedings of the 8th Conference on Geometry and Topology of Manifolds
Kubarski, Jan; Poncin, Norbert UL; Wolak, Robert

Book published by Faculty of Science, Technology and Communication, University of Luxembourg (2008)

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See detailTransmission of values and intergenerational Solidarity in Luxembourg
Michels, Tom UL; Albert, Isabelle UL; Ries, Thierry et al

in Presented at the 4th Congress of the European Society on Family Relations. Jyväskylä, Finland. (2008)

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See detailComment articuler la linguistique et la sémiostylistique ? Le champ stylistique à l'épreuve de la matérialité de l'écrit
Colas-Blaise, Marion UL

in Actes du Congrès mondial de linguistique française (2008)

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See detailComputer-Based School System Monitoring with Feedback to Teachers
Plichart, P.; Busana, Gilbert UL; Martin, Romain UL et al

in Proceedings of World Conference on Educational Multimedia, Hypermedia and Telecommunications (2008)

Educational multimedia focuses traditionally on the design of computer aided learning environments. Evaluation has to be viewed as an essential part of the learning environment. Beyond opportunities ... [more ▼]

Educational multimedia focuses traditionally on the design of computer aided learning environments. Evaluation has to be viewed as an essential part of the learning environment. Beyond opportunities provided by its computerization (behaviours tracking, richer interactions, etc.), Computer Based Assessment provides teachers a measurement instrument where their students are put together with larger groups of students on the same assessment scale, using a unique competency model. It provides feedback to teachers that enable them to early detect shortcomings of their courses, pedagogical approach. ICT provides in this case a flexible way for the results collection, feedback reporting raising strengths and weaknesses, assurance of anonymity, data privacy. Moreover, it would give decision makers of the educational system information on the educational system steering efficiency. This paper describes ongoing assessment based on the TAO platform with feedback to teachers done in Luxembourg. [less ▲]

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See detailWhat makes a problem complex? Factors determining difficulty in dynamic situations and implications for diagnosing complex problem solving competence
Greiff, Samuel UL; Funke, Joachim

in Zumbach, Joerg; Schwartz, Neil; Seufert, Tina (Eds.) et al Beyond knowledge: the legacy of competence (2008)

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See detailOn the dynamics of capital accumulation across space
Camacho, Carmen; Zou, Benteng UL; Briani, Maya

in European Journal of Operational Research (2008), 186(2), 451-465

We solve an optimal growth model in continuous space, continuous and bounded time. The optimizer chooses the optimal trajectories of capital and consumption across space and time by maximizing an ... [more ▼]

We solve an optimal growth model in continuous space, continuous and bounded time. The optimizer chooses the optimal trajectories of capital and consumption across space and time by maximizing an objective function with both space and time discounting. We extract the corresponding Pontryagin conditions and prove their sufficiency. We end up with a system of two parabolic differential equations with the corresponding boundary conditions. We propose a simple numerical set-up to simulate PDE systems which we employ to study the roles of initial capital and technology distributions over space in various scenarios. [less ▲]

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See detailConviviality masks in multiagent systems
Caire, Patrice UL; Villata, Serena; Boella, Guido et al

in Conviviality Masks in Multiagent Systems (2008)

In this paper we study tools for conviviality to develop user-friendly multiagent systems. First, we show how to use the social-cognitive concept of conviviality in multiagent system technology by ... [more ▼]

In this paper we study tools for conviviality to develop user-friendly multiagent systems. First, we show how to use the social-cognitive concept of conviviality in multiagent system technology by relating it to agent power and social dependence networks. Second, we de- fine conviviality masks as transformations of social dependencies by hiding power relations and social structures to facilitate social interactions. Third, we introduce dynamic dependence networks to model the creation of conviviality using conviviality masks. We illustrate the use of conviviality masks with a multiagent telecon- ferencing application for virtual worlds. [less ▲]

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See detailMultiplikatorenschulung oder wie Fremdsprachenlehrende zu WeiterbildnerInnen werden
Höppner, Kristina D. C. UL; Bosch, Hildegard

Book published by Hueber (2008)

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See detailCa2+-dependent regulation of NOX2 activity via MRP proteins in HL-60 granulocytes
Schenten, Véronique UL; Bréchard, Sabrina UL; Melchior, Chantal UL et al

in Calcium Binding Proteins (2008), 3(1), 25-30

Recently, two proteins of the S100 protein family, the myeloid-related calcium-binding proteins MRP-8 and MRP-14 have been implicated in the Ca2+-induced activation of the neutrophil NADPH oxidase (NOX2 ... [more ▼]

Recently, two proteins of the S100 protein family, the myeloid-related calcium-binding proteins MRP-8 and MRP-14 have been implicated in the Ca2+-induced activation of the neutrophil NADPH oxidase (NOX2) but the mechanism underlying this process remains unclear. In this study, the role of MRP-8/14 in the Ca2+-dependent regulation of NOX2 activity was characterized in neutrophil-like HL-60 cells using small interfering RNAs (siRNAs) to knock-down endogenous MRP-8 and/or MRP-14 expression. Real-time PCR and Western blot revealed that MRP-8 and MRP-14 expression was 20 times higher in dimethylsulfoxide-differentiated neutrophil-like HL-60 cells compared to quiescent HL-60 cells. Knock-down of MRP-8 and MRP-14 in differentiated HL-60 cells decreased protein levels by 30 and 45% respectively. The impact of the reduced MRP-8/14 protein expression on NOX2 activity was investigated by measuring fMLF-induced H2O2 production. In cells simultaneously transfected with MRP-8 and MRP14 siRNAs, H2O2 production was reduced by 50%, suggesting that both MRP-8 and MRP-14 are required for NOX2 activity; single knock-downs were inefficient. To elucidate the role of Ca2+ in MRP8/14, and consequently in NOX2 activation, siRNA-transfected cells were treated with the Ca2+ ionophore ionomycin prior to stimulation with PMA, a Ca2+-independent protein kinase C activator. PMA-induced H2O2 production was enhanced by ionomycin. This amplification of NOX2 activity was abolished by MRP8/14 knock-down, indicating that both MRP-8 and MRP-14 are necessary to regulate Ca2+-induced NOX2 activation. Taken together, our results suggest that the mechanism of MRPs activation is highly dependent on the increase of intracellular Ca2+ level for a full activation of NOX2. [less ▲]

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See detailSonderschule behindert Chancengleichheit
Powell, Justin J W UL; Pfahl, Lisa

in WZBrief Bildung (2008), (4),

Gleicher Zugang zu Bildung für alle: Das fordert die UN-Konvention über die Rechte behinderter Menschen, die 2009 verbindlich für Deutschland wird. Mit dem deutschen Sonderschulsystem, das fast alle ... [more ▼]

Gleicher Zugang zu Bildung für alle: Das fordert die UN-Konvention über die Rechte behinderter Menschen, die 2009 verbindlich für Deutschland wird. Mit dem deutschen Sonderschulsystem, das fast alle Schüler mit besonderem Förderbedarf aufnimmt, ist Chancengleichheit nicht gewährleistet. 80 Prozent der Abgänger von Sonderschulen erhalten keinen qualifizierenden Abschluss. Beispiele aus dem In- und Ausland zeigen, dass inklusiver Unterricht erfolgversprechender ist. [less ▲]

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See detailChanges of Glucocorticoid receptor first exon variants in major depressive disorder
Alt, Simone UL; Turner, Jonathan D.; Klok, Melanie D. et al

Scientific Conference (2008)

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See detailResolving Environmental Disputes: From Conflict to Consensus
Affolderbach, Julia UL

in Environmental Politics (2008), 17(1), 169-170

Detailed reference viewed: 90 (1 UL)