References of "2008"
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See detailDigital inequality among U.S. Latinos: What do we know? What do we want to know?
Rivas, Salvador UL

in Williams, Kate (Ed.) Understanding and Implementing Local Community Use of Information Technology (2008, March 28)

Chapter discredits the idea that most Americans are online, pointing out that African Americans and Latinos are 1/3 as likely to have a computer at home, are less employed so less online at work, and ... [more ▼]

Chapter discredits the idea that most Americans are online, pointing out that African Americans and Latinos are 1/3 as likely to have a computer at home, are less employed so less online at work, and Latino immigrants may not be aware of community resources like public access computers at the library. The chapter also describes past and present ideas as to why this difference persists. [less ▲]

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See detailGeoGebra
Hohenwarter, Markus; Borcherds, Michael; Kreis, Yves UL

Software (2008)

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See detailExternal Relations of the European Union
Lickova, Magdalena UL

Speeches/Talks (2008)

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See detailKann ein DGS den Geometrieunterricht für alle Kinder verändern?
Kreis, Yves UL

Scientific Conference (2008, March 13)

Eine Dynamische Geometrie Software (DGS) setzt das Handeln der Kinder in den Vordergrund. Die Schüler manipulieren ein Programm, das ihnen erlaubt Änderungen in geometrischen Figuren visuell zu erfassen ... [more ▼]

Eine Dynamische Geometrie Software (DGS) setzt das Handeln der Kinder in den Vordergrund. Die Schüler manipulieren ein Programm, das ihnen erlaubt Änderungen in geometrischen Figuren visuell zu erfassen und experimentell zu beeinflussen. Dieser dynamische Umgang mit den einzelnen mathematischen Objekten in einem entdeckenden Unterricht bewirkt vermutlich ein besseres Verständnis der elementaren Geometriekenntnisse bei allen Kindern. In dem DGS GeoGebra werden zusätzlich zu der grafischen Darstellung die dazugehörigen algebraischen Ausdrücke (z.B. Koordinaten, Länge, Umfang) angezeigt. Eine Änderung dieser Ausdrücke bewirkt auch eine Änderung der geometrischen Objekte und umgekehrt. Somit können die Kinder die Formeln des Umfangs und des Flächeninhalts experimentell entdecken und anschließend direkt in GeoGebra anwenden. [less ▲]

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See detailEuropean Exceptionalism in International Law
Lickova, Magdalena UL

Speeches/Talks (2008)

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See detailWeighted lattice polynomials of independent random variables
Marichal, Jean-Luc UL

in Discrete Applied Mathematics (2008), 156(5), 685-694

We give the cumulative distribution functions, the expected values, and the moments of weighted lattice polynomials when regarded as real functions of independent random variables. Since weighted lattice ... [more ▼]

We give the cumulative distribution functions, the expected values, and the moments of weighted lattice polynomials when regarded as real functions of independent random variables. Since weighted lattice polynomial functions include ordinary lattice polynomial functions and, particularly, order statistics, our results encompass the corresponding formulas for these particular functions. We also provide an application to the reliability analysis of coherent systems. [less ▲]

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See detailThe roles of "face" and "non-face" areas during individual face perception: Evidence by fmri adaptation in a brain-damaged prosopagnosic patient
Dricot, Laurence; Sorger, Bettina; Schiltz, Christine UL et al

in NeuroImage (2008), 40(1), 318-332

Two regions in the human occipito-temporal cortex respond preferentially to faces: 'the fusiform face area' ('FFA') and the 'occipital face area' ('OFA'). Whether these areas have a dominant or exclusive ... [more ▼]

Two regions in the human occipito-temporal cortex respond preferentially to faces: 'the fusiform face area' ('FFA') and the 'occipital face area' ('OFA'). Whether these areas have a dominant or exclusive role in face perception, or if sub-maximal responses in other visual areas such as the lateral occipital complex (LOC) are also involved, is currently debated. To shed light on this issue, we tested normal participants and PS, a well-known brain-damaged patient presenting a face-selective perception deficit (prosopagnosia) [Rossion, B., Caldara, R., Seghier, M., Schuller, A. M., Lazeyras, F., Mayer, E. (2003). A network of occipito-temporal face-sensitive areas besides the right middle fusiform gyrus is necessary for normal face processing. Brain 126 2381-2395.], with functional magnetic resonance imaging (fMRI). Of particular interest, the right hemisphere lesion of the patient PS encompasses the 'OFA' but preserves the 'FFA' and LOC [Sorger, B., Goebel, R., Schiltz, C., Rossion, B. (2007). Understanding the functional neuroanatomy of acquired prosopagnosia. NeuroImage 35, 836-852.]. Using fMRI-adaptation, we found a dissociation between the coding of individual exemplars in the structurally intact 'FFA', which was impaired for faces but preserved for objects in the patient PS's brain. Most importantly, a larger response to different faces than repeated faces was found in the ventral part of the LOC both for normals and the patient, next to the right hemisphere lesion. Thus, following prosopagnosia, areas that do not respond preferentially to faces such as the ventral part of the LOC (vLOC) may still be recruited for compensatory or residual individual face perception. Overall, these observations indicate that several high-level visual areas in the human brain contribute to individual face perception. However, a subset of these areas in the right hemisphere, those responding preferentially to faces ('FFA' and 'OFA'), appear to be critical for this function. [less ▲]

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See detailEuropean Exceptionalism in International Law
Lickova, Magdalena UL

in European Journal of International Law (2008), 19(3), 463-490

For Member States of the European Union, participation in this supranational organization has increased the number of diffi culties in the international arena. Occasionally, the expanding legislative ... [more ▼]

For Member States of the European Union, participation in this supranational organization has increased the number of diffi culties in the international arena. Occasionally, the expanding legislative activity of the European institutions reaches out beyond the borders of the European legal system and incidentally affects the EU Member States ’ autonomous relations with third parties. Consequently the EU and its members, often with success, seek third parties ’ consent to exceptional treatment. Because of their number and significance, such derogations have inspired this article to inquire into their expansion and legal status under international law. Even though the EU-related exceptions have not created an international customary rule, the article observes that European integration shapes international rules in diverse fi elds and adjusts them to its needs. Since European integration is designed to administerand regulate an increasing number of issues, the autonomous international obligations of the EU Member States may become an obstacle. Because the European Union is likely to continue using special treatment in the future, it is important to assess how far the supranational exception can go in order to accommodate all interests at stake. [less ▲]

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See detailAgency Work and the Idea of Dual Employership
Ratti, Luca UL

Presentation (2008, March)

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See detailYes and PI3K bind CD95 to signal invasion of glioblastoma.
Kleber, Susanne; Sancho-Martinez I; Wiestler B et al

in Cancer Cell (2008), 13

Invasion of surrounding brain tissue by isolated tumor cells represents one of the main obstacles to a curative therapy of glioblastoma multiforme. Here we unravel a mechanism regulating glioma ... [more ▼]

Invasion of surrounding brain tissue by isolated tumor cells represents one of the main obstacles to a curative therapy of glioblastoma multiforme. Here we unravel a mechanism regulating glioma infiltration. Tumor interaction with the surrounding brain tissue induces CD95 Ligand expression. Binding of CD95 Ligand to CD95 on glioblastoma cells recruits the Src family member Yes and the p85 subunit of phosphatidylinositol 3-kinase to CD95, which signal invasion via the glycogen synthase kinase 3-beta pathway and subsequent expression of matrix metalloproteinases. In a murine syngeneic model of intracranial GBM, neutralization of CD95 activity dramatically reduced the number of invading cells. Our results uncover CD95 as an activator of PI3K and, most importantly, as a crucial trigger of basal invasion of glioblastoma in vivo. [less ▲]

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See detailSacro e medium cinematografico: analisi figurale di "Madre e figlio" di Sokurov
Tore, Gian Maria UL

in E/C (revue en ligne de l’Associazione Italiana di Studi Semiotici) (2008)

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See detailMulti-dimensional Interactive City Exploration through Mixed Reality
Herbst, Iris; Braun, Anne-Kathrine; McCall, Roderick UL et al

in Multi-dimensional Interactive City Exploration through Mixed Reality (2008, March)

In this paper we present a pervasive outdoor mixed reality edutainment game for exploring the history of a city in the spatial and the temporal dimension, which will closely couple the real environment ... [more ▼]

In this paper we present a pervasive outdoor mixed reality edutainment game for exploring the history of a city in the spatial and the temporal dimension, which will closely couple the real environment with the virtual content. The game provides a new and unique user experience, which links rich interactive content to time and places. We introduce the development of such a game, including a universal mechanism to define and setup multi-modal user interfaces for game challenges. [less ▲]

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See detailDas Gedächtnis für forensische Personinformationen bei Vollzugpsychologen
Glock, Sabine; Kneer, Julia; Krolak-Schwerdt, Sabine UL

Scientific Conference (2008, March)

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See detailMicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
Sinkkonen, Lasse UL; Hugenschmidt, Tabea; Berninger, Philipp et al

in Nature Structural and Molecular Biology (2008), 15(3), 259-67

Loss of microRNA (miRNA) pathway components negatively affects differentiation of embryonic stem (ES) cells, but the underlying molecular mechanisms remain poorly defined. Here we characterize changes in ... [more ▼]

Loss of microRNA (miRNA) pathway components negatively affects differentiation of embryonic stem (ES) cells, but the underlying molecular mechanisms remain poorly defined. Here we characterize changes in mouse ES cells lacking Dicer (Dicer1). Transcriptome analysis of Dicer-/- cells indicates that the ES-specific miR-290 cluster has an important regulatory function in undifferentiated ES cells. Consistently, many of the defects in Dicer-deficient cells can be reversed by transfection with miR-290 family miRNAs. We demonstrate that Oct4 (also known as Pou5f1) silencing in differentiating Dicer-/- ES cells is accompanied by accumulation of repressive histone marks but not by DNA methylation, which prevents the stable repression of Oct4. The methylation defect correlates with downregulation of de novo DNA methyltransferases (Dnmts). The downregulation is mediated by Rbl2 and possibly other transcriptional repressors, potential direct targets of miR-290 cluster miRNAs. The defective DNA methylation can be rescued by ectopic expression of de novo Dnmts or by transfection of the miR-290 cluster miRNAs, indicating that de novo DNA methylation in ES cells is controlled by miRNAs. [less ▲]

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See detailIGEB-Konferenz in Echternach
Sagrillo, Damien UL

in Revue Musicale (2008)

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See detail"Der Anfang vom Ende ist immer diskret". Von Enzensbergers "Kursbuch" zum "Untergang der Titanic"
Marmulla, Henning UL

in Der Deutschunterricht: Beiträge zu seiner Praxis und wissenschaftlichen Grundlegung (2008), 1

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See detailRegionale Schwerefeldmodellierung durch Slepian- und radiale Basisunktionen
Antoni, M.; Keller, W.; Weigelt, Matthias UL

in Zeitschrift für Vermessungswesen (2008), 133(2), 120--129

Zur Erfassung des statischen und des zeitvariablen Gravitati- onsfeldes der Erde sind seit 2000 bzw. seit 2002 die beiden Satellitenmissionen CHAMP und GRACE im Orbit. Üblicher- weise wird das aus den ... [more ▼]

Zur Erfassung des statischen und des zeitvariablen Gravitati- onsfeldes der Erde sind seit 2000 bzw. seit 2002 die beiden Satellitenmissionen CHAMP und GRACE im Orbit. Üblicher- weise wird das aus den Missionsdaten abgeleitete Gravita- tionsfeld als Summe von Kugelfunktionen dargestellt. Es zeigt sich aber, dass diese global definierten Basisfunktionen nicht in der Lage sind, alle in den Daten enthaltenen lokalen De- tails zu repräsentieren. Der Beitrag stellt zwei Methoden dar, das verbleibende Restsignal durch lokale Basisfunktionen auf- zulösen. Zum einen werden die radialen Basisfunktionen ver- wendet, zum anderen die Slepianfunktionen, die durch Or- thogonalisierung der Kugelflächenfunktionen auf einem vor- gegebenen Teil der Kugeloberfläche entstehen. Werden alle Parameter der radialen Basisfunktionen geschätzt, so erfor- dert das nichtlineare Problem neben den Startwerten auch eine Strahlminimierung, die die Konvergenz der Lösung ver- bessert, und ein Penalty-Verfahren, damit die geschätzten Parameter in einem sinnvollen Intervall fixiert werden. In ei- ner Simulationsstudie werden die erreichbaren Genauigkeiten und der numerische Aufwand beider Funktionensysteme mit- einander verglichen. [less ▲]

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