![]() ![]() ; Steffgen, Georges ![]() Poster (2008, May) Detailed reference viewed: 145 (0 UL)![]() ![]() Pignault, Anne ![]() Scientific Conference (2008, May) Detailed reference viewed: 38 (0 UL)![]() ![]() Dorosz, Sven ![]() in Physical Review. E ,Statistical, Nonlinear, and Soft Matter Physics (2008), 77(5), Detailed reference viewed: 101 (1 UL)![]() ![]() Sagrillo, Damien ![]() in Revue Musicale (2008) Detailed reference viewed: 75 (2 UL)![]() Bund, Andreas ![]() in BrandlBredenbeck, H.-P.; Stefanie, M. (Eds.) Schulen in Bewegung - Schulsport in Bewegung (2008, May) Detailed reference viewed: 89 (1 UL)![]() Bund, Andreas ![]() Scientific Conference (2008, May) Detailed reference viewed: 68 (1 UL)![]() Freyermuth, Sylvie ![]() Presentation (2008, April 24) Detailed reference viewed: 43 (0 UL)![]() Meyers, Christian ![]() Presentation (2008, April 16) Detailed reference viewed: 32 (0 UL)![]() ; ; et al in Diabetes (2008), 57(4), 929-937 OBJECTIVE: We investigated the association of anti-inflammatory cytokine interleukin (IL)-1 receptor antagonist (IL-1ra), adiponectin, proinflammatory cytokines IL-1 beta, IL-6, and CCL2, and tumor ... [more ▼] OBJECTIVE: We investigated the association of anti-inflammatory cytokine interleukin (IL)-1 receptor antagonist (IL-1ra), adiponectin, proinflammatory cytokines IL-1 beta, IL-6, and CCL2, and tumor necrosis factor-alpha with beta-cell function, metabolic status, and clinical remission in patients with recent-onset type 1 diabetes. RESEARCH DESIGN AND METHODS: Serum was obtained from 256 newly diagnosed patients (122 males and 134 females, median age 9.6 years). Stimulated C-peptide, blood glucose, and A1C were determined in addition to circulating concentration of cytokines at 1, 6, and 12 months after diagnosis. Analyses were adjusted for sex, age, and BMI percentile. RESULTS: Anti-inflammatory IL-1ra was positively associated with C-peptide after 6 (P = 0.0009) and 12 (P = 0.009) months. The beneficial association of IL-1ra on beta-cell function was complemented by the negative association of IL-1 beta with C-peptide after 1 month (P = 0.009). In contrast, anti-inflammatory adiponectin was elevated in patients with poor metabolic control after 6 and 12 months (P < 0.05) and positively correlated with A1C after 1 month (P = 0.0004). Proinflammatory IL-6 was elevated in patients with good metabolic control after 1 month (P = 0.009) and showed a positive association with blood glucose disposal after 12 months (P = 0.047). CONCLUSIONS: IL-1ra is associated with preserved beta-cell capacity in type 1 diabetes. This novel finding indicates that administration of IL-1ra, successfully improving beta-cell function in type 2 diabetes, may also be a new therapeutic approach in type 1 diabetes. The relation of adiponectin and IL-6 with remission and metabolic status transfers observations from in vitro and animal models into the human situation in vivo. [less ▲] Detailed reference viewed: 87 (0 UL)![]() ![]() de Saint-Georges, Ingrid ![]() Scientific Conference (2008, April) Detailed reference viewed: 93 (0 UL)![]() ; ; Bund, Andreas ![]() in Ze-phir : Informationen für den Sportwissenschaftlichen Nachwuchs (2008), 15(1), 27-30 Detailed reference viewed: 91 (0 UL)![]() Bund, Andreas ![]() in Revista de Psicología del Deporte (2008), 17(1), 71-83 Detailed reference viewed: 55 (0 UL)![]() Bund, Andreas ![]() in Ze-phir : Informationen für den Sportwissenschaftlichen Nachwuchs (2008), 15(1), 9-14 Detailed reference viewed: 56 (0 UL)![]() Bund, Andreas ![]() in Sudeck, G.; Conzelmann, A.; Lehnert, K. (Eds.) et al Differentielle Sportpsychologie - Sportwissenschaftliche Persönlichkeitsforschung (2008, April) Detailed reference viewed: 58 (0 UL)![]() Bricocoli, Massimo ![]() in Social Policy and Administration (2008), 42(2), 143-159 This article deals with the development of local welfare in Italy and is grounded on a research project focusing on activation as a main feature of change in Italian social policies. Along with ... [more ▼] This article deals with the development of local welfare in Italy and is grounded on a research project focusing on activation as a main feature of change in Italian social policies. Along with decentralization processes, many Italian regions have been acting as policy laboratories, developing and testing very different approaches according to their political attitude. On the one hand this results in a fragmented policy landscape which is difficult to recompose, and, moreover, in growing inequalities in the Italian welfare system. On the other hand, it opens opportunities for experimentation on institutional and organizational structures on a regional scale, creating a variety of practices for research and policy analysis. In the article we first describe the main trends in national social policies, with a specific focus on the dynamics of change referring to activation. We will then focus on a pilot programme which is aiming at the promotion and implementation of innovative practices in health and social care services in Friuli-Venezia Giulia, a region in which there is a significant orientation towards enhancing social citizenship and enforcing the central position of the public actor. We investigate how the dynamics of territorialization and personalization, implied by the programme, trigger specific logics and practices of activation. Finally, referring to this case study, we propose an analytical overview of some relevant issues in the development of ‘local active welfare’ in Italy. [less ▲] Detailed reference viewed: 111 (1 UL)![]() Engel de Abreu, Pascale ![]() ![]() Poster (2008, April) Working memory, the capacity to store and manipulate information over brief periods of time (Baddeley & Hitch, 1974) is suggested to play a crucial role in children’s language acquisition in native and ... [more ▼] Working memory, the capacity to store and manipulate information over brief periods of time (Baddeley & Hitch, 1974) is suggested to play a crucial role in children’s language acquisition in native and foreign languages (e.g. Gathercole, 2006; Service, 1992). The present study investigated children’s working memory skills and vocabulary knowledge in their native and secondary languages in the context of immigration. Twenty Portuguese immigrant children growing up in Luxembourg, who speak Portuguese at home, and acquire Luxembourgish in a natural setting and German through scholastic instruction, participated in the study. Children were assessed on measures of phonological short-term memory (digit recall and nonword repetition) and complex working memory (counting recall and backwards digit recall) in both Luxembourgish and Portuguese, on vocabulary knowledge (Portuguese, Luxembourgish, and German) and on comprehension (Luxembourgish and German). The children were compared to three groups of monolingual children: 20 Luxembourgish speakers living in Luxembourg and 40 Portuguese speakers from Brazil growing up in families of high (N=20) and low (N=20) socio economical status (SES). Groups were matched on age (7 years), nonverbal ability and gender. In the Portuguese immigrant children, language competences in Portuguese, Luxembourgish, and German were at an equivalent level that fell below the linguistic competence of native speakers from Brazil and from Luxembourg. The 4 groups did not differ on two of the four working memory measures. On one of the complex working memory tasks (counting recall) the low SES group from Brazil manifested scores that fell below the three other groups. Finally, the Portuguese immigrant children performed equally well to their Brazilian counterparts in the repetition of the Portuguese sounding nonwords, whereas their performance in the repetition of the Luxembourgish nonwords fell below that of the native Luxembourgish speakers. These results are consistent with findings that phonological short-term memory performance is better for familiar rather than unfamiliar lexical material (Gathercole, 1995). As the Portuguese immigrant children and their monolingual peers from Luxembourg and Brazil performed at comparable levels on the working memory measures, their poor language performances in all three languages is unlikely to be related to a fundamental cognitive deficit. Their even lower knowledge of Portuguese, vocabulary than children from impoverished backgrounds in Brazil also rules out the hypothesis that their poor language skills are simply a reflection of lower socio-economical status. Instead, the findings appear to be a direct consequence of growing up as an immigrant in a multilingual society. [less ▲] Detailed reference viewed: 151 (4 UL)![]() ![]() Neframi, Eleftheria ![]() in Revue du Marché Commun et de l'Union Européenne (2008) Detailed reference viewed: 114 (0 UL)![]() ![]() Sagrillo, Damien ![]() Scientific Conference (2008, April) Detailed reference viewed: 66 (1 UL)![]() Sagrillo, Damien ![]() Scientific Conference (2008, April) Detailed reference viewed: 64 (0 UL)![]() Bund, Andreas ![]() Presentation (2008, April) Detailed reference viewed: 77 (0 UL) |
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