![]() Cicotti, Claudio ![]() Article for general public (2005) Detailed reference viewed: 55 (1 UL)![]() Carr, Constance ![]() Presentation (2005, May) Detailed reference viewed: 77 (0 UL)![]() ![]() Schiltz, Christine ![]() Scientific Conference (2005, May) Detailed reference viewed: 123 (0 UL)![]() Marichal, Jean-Luc ![]() in Aequationes Mathematicae (2005), 69(3), 309-320 Comparison meaningful functions acting on some real interval E are completely described as transformed coordinate projections on minimal invariant subsets. The case of monotone comparison meaningful ... [more ▼] Comparison meaningful functions acting on some real interval E are completely described as transformed coordinate projections on minimal invariant subsets. The case of monotone comparison meaningful functions is further specified. Several already known results for comparison meaningful functions and invariant functions are obtained as consequences of our description. [less ▲] Detailed reference viewed: 99 (5 UL)![]() Weigelt, Matthias ![]() Scientific Conference (2005, May) Detailed reference viewed: 32 (0 UL)![]() Reckinger, Rachel ![]() Presentation (2005, May) Detailed reference viewed: 87 (0 UL)![]() Bund, Andreas ![]() Scientific Conference (2005, May) Detailed reference viewed: 49 (0 UL)![]() Bund, Andreas ![]() Scientific Conference (2005, May) Detailed reference viewed: 67 (1 UL)![]() Van Baars, Stefan ![]() in Geotechnique (2005), 55(4), 319-323 Detailed reference viewed: 141 (2 UL)![]() Bund, Andreas ![]() in Seelig, Harald; Göhner, Wiebke; Fuchs, Reinhard (Eds.) Selbststeuerung im Sport (2005, May) Detailed reference viewed: 67 (0 UL)![]() Sinkkonen, Lasse ![]() in Nucleic Acids Research (2005), 33(8), 2440-51 The candidate human tumor suppressor gene cyclin C is a primary target of the anti-proliferative hormone 1alpha,25-dihydroxyvitamin D3 [1alpha,25(OH)2D3], but binding sites for the 1alpha,25(OH)2D3 ... [more ▼] The candidate human tumor suppressor gene cyclin C is a primary target of the anti-proliferative hormone 1alpha,25-dihydroxyvitamin D3 [1alpha,25(OH)2D3], but binding sites for the 1alpha,25(OH)2D3 receptor (VDR), so-called 1alpha,25(OH)2D3 response elements (VDREs), have not yet been identified in the promoter of this gene. We screened various cancer cell lines by quantitative PCR and found that the 1alpha,25(OH)2D3 inducibility of cyclin C mRNA expression, in relationship with the 24-hydroxylase (CYP24) gene, was best in MCF-7 human breast cancer cells. To characterize the molecular mechanisms, we analyzed 8.4 kb of the cyclin C promoter by using chromatin immunoprecipitation assays (ChIP) with antibodies against acetylated histone 4, VDR and its partner receptor, retinoid X receptor (RXR). The histone 4 acetylation status of all 23 investigated regions of the cyclin C promoter did not change significantly in response to 1alpha,25(OH)2D3, but four independent promoter regions showed a consistent, 1alpha,25(OH)2D3-dependent association with VDR and RXR over a time period of 240 min. Combined in silico/in vitro screening identified in each of these promoter regions a VDRE and reporter gene assays confirmed their functionality. Moreover, re-ChIP assays monitored simultaneous association of VDR with RXR, coactivator, mediator and RNA polymerase II proteins on these regions. Since cyclin C protein is associated with those mediator complexes that display transcriptional repressive properties, this study contributes to the understanding of the downregulation of a number of secondary 1alpha,25(OH)2D3-responding genes. [less ▲] Detailed reference viewed: 228 (9 UL)![]() Krebs, Stefan ![]() in Sehepunkte (2005), 5(4), Detailed reference viewed: 255 (0 UL)![]() ![]() Wollscheid-Lengeling, Evi ![]() in Science (2005), 2005(15), A recent European Molecular Biology Laboratory Conference on Science and Society entitled "Time & Aging--Mechanisms & Meanings" fascinated scientists from different research areas as well as nonscientists ... [more ▼] A recent European Molecular Biology Laboratory Conference on Science and Society entitled "Time & Aging--Mechanisms & Meanings" fascinated scientists from different research areas as well as nonscientists. Topics discussed included not only the biological aging process but also the psychological effects of aging and social influences that affect this process. [less ▲] Detailed reference viewed: 22 (0 UL)![]() Marichal, Jean-Luc ![]() Presentation (2005, April 08) Detailed reference viewed: 33 (1 UL)![]() Steffgen, Georges ![]() Article for general public (2005) Detailed reference viewed: 77 (6 UL)![]() Rivas, Salvador ![]() Poster (2005, April) Previous studies that describe the existence and dimensions of the digital divide call attention to the potential negative consequences of not having access to a computer and not being online. Missing ... [more ▼] Previous studies that describe the existence and dimensions of the digital divide call attention to the potential negative consequences of not having access to a computer and not being online. Missing from these studies, however, is a more thorough investigation of how the effect of race/ethnicity on computer ownership is mediated by associated factors and how these effects have changed across time. The current study attempts to fill these gaps. Using Current Population Survey data, from 1984 to 2003, I estimate a series of logistic regression models on computer ownership at the household level. After controlling for demographic, household composition, and socioeconomic variables, the gap between Black and Hispanic households in relation to White households remains statistically significant. For Asian households, the racial effect is explained by the variables in the models. The implications of these findings are discussed and suggestions are made for future research. [less ▲] Detailed reference viewed: 62 (1 UL)![]() Steffgen, Georges ![]() Article for general public (2005) Detailed reference viewed: 140 (10 UL)![]() ![]() ; Krolak-Schwerdt, Sabine ![]() Scientific Conference (2005, April) Detailed reference viewed: 43 (0 UL)![]() Weigelt, Matthias ![]() Diverse speeches and writings (2005) Detailed reference viewed: 40 (2 UL)![]() Marichal, Jean-Luc ![]() in Computers and Operations Research (2005), 32(4), 861-877 We analyze a recently proposed ordinal sorting procedure (Tomaso) for the assignment of alternatives to graded classes and we present a freeware constructed from this procedure. We illustrate it by two ... [more ▼] We analyze a recently proposed ordinal sorting procedure (Tomaso) for the assignment of alternatives to graded classes and we present a freeware constructed from this procedure. We illustrate it by two examples, and do some testing in order to show its usefulness. [less ▲] Detailed reference viewed: 155 (5 UL) |
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