References of "2005"
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See detailHeuristiek voor het Historisch-Pedagogisch Onderzoek en de Waarde van het Internet. Over de Concrete Zoektocht naar het Pedagogisch Verleden
Henkens, Bregt; Catteeuw, Karl; Thyssen, Geert UL

in Depaepe, Mark; Simon, Frank; Van Gorp, Angelo (Eds.) Paradoxen van Pedagogisering. Handboek Pedagogische Historiografie (2005)

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See detailLa recherche sur la Première Guerre mondiale : un champ disciplinaire en plein développement
Majerus, Benoît UL; Amara, Michael; Jaumain, Serge et al

in Amara, Michael; Jaumain, Serge; Majerus, Benoît (Eds.) et al Une ‘guerre totale’? La Belgique dans la Première Guerre mondiale. Nouvelles tendances de la recherche historique (2005)

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See detailCAMPUS: a generic framework for Computer Assisted Mathematical Problem Understanding and Solving
Busana, Gilbert UL; Martin, Romain UL

in Proceedings of the world conference on educational media, hypermedia and telecommunications 2005 (2005)

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See detailAre solvation free energies of homogeneous helical peptides additive?
Staritzbichler, R.; Gu, Wei UL; Helms, V.

in Journal of Physical Chemistry B (2005), 109(40), 19000-19007

We investigated the additivity of the solvation free energy of amino acids in homogeneous helices of different length in water and in chloroform. Solvation free energies were computed by ... [more ▼]

We investigated the additivity of the solvation free energy of amino acids in homogeneous helices of different length in water and in chloroform. Solvation free energies were computed by multiconfiguration thermodynamic integration involving extended molecular dynamics simulations and by applying the generalized-born surface area solvation model to static helix geometries. The investigation focused on homogeneous peptides composed of uncharged amino acids, where the backbone atoms are kept fixed in an ideal helical conformation. We found nonlinearity especially for short peptides, which does not allow a simple treatment of the interaction of amino acids with their surroundings. For homogeneous peptides longer than five residues, the results from both methods are in quite good agreement and solvation energies are to a good extent additive. [less ▲]

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See detailCyclophilin a binds to linear peptide motifs containing a consensus that is present in many human proteins
Piotukh, K.; Gu, Wei UL; Kofler, M. et al

in Journal of Biological Chemistry (2005), 280(25), 23668-23674

Cyclophilin A ( CypA) is a peptidyl-prolyl cis/trans-isomerase that is involved in multiple signaling events of eukaryotic cells. It might either act as a catalyst for prolyl bond isomerization, or it can ... [more ▼]

Cyclophilin A ( CypA) is a peptidyl-prolyl cis/trans-isomerase that is involved in multiple signaling events of eukaryotic cells. It might either act as a catalyst for prolyl bond isomerization, or it can form stoichiometric complexes with target proteins. We have investigated the linear sequence recognition code for CypA by phage display and found the consensus motif FGPXLp to be selected after five rounds of panning. The peptide FGP-DLPAGD showed inhibition of the isomerase reaction and NMR chemical shift mapping experiments highlight the CypA interaction epitope. Ligand docking suggests that the peptide was able to bind to CypA in the cis- and trans-conformation. Protein Data Bank searches reveal that many human proteins contain the consensus motif, and several of these protein motifs are shown to interact with CypA in vitro. These sequences represent putative target sites for binding of CypA to intracellular proteins. [less ▲]

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See detailPädagogik und Pragmatismus. Gesellschaftstheorie und die Entwicklung der Pädagogik
Tröhler, Daniel UL; Oelkers, Jürgen

Book published by Pestalozzianum (2005)

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See detailDynamical binding of proline-rich peptides to their recognition domains
Gu, Wei UL; Helms, V.

in Biochimica et Biophysica Acta-Proteins and Proteomics (2005), 1754(1-2), 232-238

Recognition of proline-rich sequences plays an important role for the assembly of multi-protein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that ... [more ▼]

Recognition of proline-rich sequences plays an important role for the assembly of multi-protein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that share characteristic features. For many complex systems containing proline-rich sequences, multiple binding modes have been found by theoretical and/or experimental studies. In this review, we discuss the different binding modes as well as the correlated dynamics of the peptides and their recognition domains, and some implications to their biological functions. Further-more, we give an outlook of the systems in the context of systems biology. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailLangue as Homeland: The Genevan of Reception of Pragmatism
Tröhler, Daniel UL

in Popkewitz, Thomas (Ed.) Inventing the Modern Self and John Dewey. Modernities and the Travelling of Pragmatism in Education (2005)

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See detailEthique et humanitaire. Mise en œuvre des pratiques de consultation et de participation
Baumann, Michèle UL; Vié Le Sage, F.

in Pédiatre (Le) (2005), (211), 2-5

Au cours des dernières décennies, l’aide humanitaire a pris un essor considérable. En même temps, elle s’est trouvée confrontée à un nombre croissant de critiques dont la plus significative est celle d ... [more ▼]

Au cours des dernières décennies, l’aide humanitaire a pris un essor considérable. En même temps, elle s’est trouvée confrontée à un nombre croissant de critiques dont la plus significative est celle d'être perçue comme un système défini et imposé par l’occident, fonctionnant sur un mode « descendant » et ayant de ce fait, une capacité d’écoute sélective. Le rôle des populations touchées dans leur propre survie est l'un des défis les plus complexes auquel le monde des acteurs humanitaires doit faire face. En particulier la prise en compte des points de vue, des attentes, des besoins exprimés, des responsabilités, des compétences des populations concernées, durant tout le cycle de la gestion du projet, est une condition indispensable à l'amélioration de la réponse humanitaire vue en tant que processus de réappropriation de la part des populations de leur pouvoir d'agir sur leur vie. A cet égard, l'idée selon laquelle une implication active du public est une condition nécessaire pour assurer le caractère éthique de toute délibération et garantir l’acceptation des interventions par les populations est aujourd'hui reconnue, mais est-elle suffisante, est elle toujours possible ? [less ▲]

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See detailVernieuwing in de Franjes? Openluchtscholen en de Traditie van Pedagogisering
Depaepe, Marc; Simon, Frank; Thyssen, Geert UL et al

in Paradoxen van Pedagogisering. Handboek Pedagogische Historiografie (2005)

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See detailPrivate or self-regulation? A comparative study of forest certification choices in Canada, the United States and Germany
Cashore, Benjamin; Van Kooten, G. Cornelis; Vertinsky, Ilan et al

in Forest Policy and Economics (2005), 7(1), 53-69

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See detailThe subsystems approach to genome annotation and its use in the project to annotate 1000 genomes.
Overbeek, Ross; Begley, Tadhg; Butler, Ralph M. et al

in Nucleic Acids Research (2005), 33(17), 5691-702

The release of the 1000th complete microbial genome will occur in the next two to three years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) launched the Project to ... [more ▼]

The release of the 1000th complete microbial genome will occur in the next two to three years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) launched the Project to Annotate 1000 Genomes. The project is built around the principle that the key to improved accuracy in high-throughput annotation technology is to have experts annotate single subsystems over the complete collection of genomes, rather than having an annotation expert attempt to annotate all of the genes in a single genome. Using the subsystems approach, all of the genes implementing the subsystem are analyzed by an expert in that subsystem. An annotation environment was created where populated subsystems are curated and projected to new genomes. A portable notion of a populated subsystem was defined, and tools developed for exchanging and curating these objects. Tools were also developed to resolve conflicts between populated subsystems. The SEED is the first annotation environment that supports this model of annotation. Here, we describe the subsystem approach, and offer the first release of our growing library of populated subsystems. The initial release of data includes 180 177 distinct proteins with 2133 distinct functional roles. This data comes from 173 subsystems and 383 different organisms. [less ▲]

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See detailExpanded metabolic reconstruction of Helicobacter pylori (iIT341 GSM/GPR): an in silico genome-scale characterization of single- and double-deletion mutants.
Thiele, Ines UL; Vo, Thuy D.; Price, Nathan D. et al

in Journal of Bacteriology (2005), 187(16), 5818-30

Helicobacter pylori is a human gastric pathogen infecting almost half of the world population. Herein, we present an updated version of the metabolic reconstruction of H. pylori strain 26695 based on the ... [more ▼]

Helicobacter pylori is a human gastric pathogen infecting almost half of the world population. Herein, we present an updated version of the metabolic reconstruction of H. pylori strain 26695 based on the revised genome annotation and new experimental data. This reconstruction, iIT341 GSM/GPR, represents a detailed review of the current literature about H. pylori as it integrates biochemical and genomic data in a comprehensive framework. In total, it accounts for 341 metabolic genes, 476 intracellular reactions, 78 exchange reactions, and 485 metabolites. Novel features of iIT341 GSM/GPR include (i) gene-protein-reaction associations, (ii) elementally and charge-balanced reactions, (iii) more accurate descriptions of isoprenoid and lipopolysaccharide metabolism, and (iv) quantitative assessments of the supporting data for each reaction. This metabolic reconstruction was used to carry out in silico deletion studies to identify essential and conditionally essential genes in H. pylori. A total of 128 essential and 75 conditionally essential metabolic genes were identified. Predicted growth phenotypes of single knockouts were validated using published experimental data. In addition, in silico double-deletion studies identified a total of 47 synthetic lethal mutants involving 67 different metabolic genes in rich medium. [less ▲]

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See detailZeitvertreib in Echtzeit? : Virtuelle Realität und ästhetische Erfahrung
Doll, Martin UL

in Karschnia, Alexander; Kohns, Oliver; Kreuzer, Stefanie (Eds.) et al Zum Zeitvertrieb : Strategien – Institutionen – Lektüren – Bilder (2005)

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See detailDie Adresse des Fake : Über das Wahre im Falschen
Doll, Martin UL

in Barth, Thomas; Betzer, Christian; Eder, Jens (Eds.) Mediale Spielräume : Erfundene Welten, Gestaltete Bilder (2005)

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See detail«La fortune iconographique et politique de la tour de Babel»
Roelens, Nathalie UL

in Contemporary French Civilization (2005)

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See detailBubble Caster – a mixed reality children application for interactive shadow play
Winkler, Thomas; Arend, Sonja; Hadley, Lia et al

in Proceedings of IDC 2005, Boulder, Colorado, USA (2005)

In this paper, we describe how the mixed reality application, Bubble Caster, technically works and how we involved children ages 7 to 8 in the design process. The children used their storytelling and ... [more ▼]

In this paper, we describe how the mixed reality application, Bubble Caster, technically works and how we involved children ages 7 to 8 in the design process. The children used their storytelling and programming skills to produce the interactive, mixed reality shadow play, The Magic Cauldron. The project enabled the children to acquire elementary programming skills in a playful learning environment. [less ▲]

Detailed reference viewed: 108 (1 UL)