Kompakte Stadt - Leitbild für Ostdeutsche Städte?

in OSWALT, Philipp (Ed.) Schrumpfende Städte. Handlungskonzepte, 2 (2005)

Neoclassical Growth and the 'Trivial' Steady State

Report (2005)

If capital is an essential input, the neoclassical growth model has a steady state with zero capital. From this, one is inclined to conclude that an economy starting without capital can never grow. We ... [more ▼]

If capital is an essential input, the neoclassical growth model has a steady state with zero capital. From this, one is inclined to conclude that an economy starting without capital can never grow. We challenge this view and claim that, if the production function satisfies the Inada conditions, a take-off is possible even though the initial capital stock is zero and capital is essential. Since the marginal product of capital is initially infinite, the ‘trivial’ steady state becomes so unstable that the solution to the equation of motion involves the possibility of a take-off, even without capital. When it happens, the take-off is spontaneous; there is no causality. [less ▲]

OAKHQOL: a new instrument to measure quality of live in knee and hip Osteoarthritis

in Journal of Clinical Epidemiology (2005), 58

To develop a questionnaire with which to measure quality of life (QoL) in patients with knee and hip osteoarthritis (OA). Study Design and Setting: Thirty-two caregivers and 96 OA patients were ... [more ▼]

To develop a questionnaire with which to measure quality of life (QoL) in patients with knee and hip osteoarthritis (OA). Study Design and Setting: Thirty-two caregivers and 96 OA patients were interviewed individually (using cognitive and face-to-face techniques) and in focus groups. A group of experts working independently at first and then consensually used the interview transcripts to generate a 46-item questionnaire. Results: Analysis of questionnaires completed by 263 patients with hip or knee OA resulted in the exclusion of three items (two because of low reliability and one because of a low response rate). Principal component analysis revealed four factors: physical activity, mental health, social functioning, and social support. A pain dimension was individualized. Preliminary testing showed the reliability of the five dimensions to be satisfactory (intraclass correlation coefficients: 0.70–0.85), construct validity was adequate when correlated with the SF36 (Spearman correlation coefficients: 0.43–0.75), and discrimination was satisfactory. The osteoarthritis knee and hip quality of life questionnaire (OAKHQOL) consists of 43 items in five dimensions and three independent items. Conclusion: TheOAKHQOLis the first specific knee and hipOAquality of life instrument. Its development followed an a priori structured strategy to ensure content validity. It meets psychometric requirements for validity and reliability. [less ▲]

Résultats de la première passation du questionnaire informatisé auprès d'une cohorte de demandeurs d'emploi au Luxembourg, Working paper n° 3.

Report (2005)

Wirtschaftsverkehr in Stadt und Umland - Ein neues Tätigkeitsfeld für "integrierte Planung"

in Verkehrszeichen : für Mobilität und Umwelt (2005), (1), 12-16

Modern city, social justice, and education Early Pragmatism as exemplified by Jane Addams

in Tröhler, Daniel; Oelkers, Jürgen (Eds.) Education and Pragmatism (2005)

Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction.

in Circulation (2005), 111(12), 1492-8

BACKGROUND: Lower mortality rates among women with chronic heart failure than among men may depend in part on the action of female sex hormones, especially estrogens. The biological effects of estrogens ... [more ▼]

BACKGROUND: Lower mortality rates among women with chronic heart failure than among men may depend in part on the action of female sex hormones, especially estrogens. The biological effects of estrogens are mediated by 2 distinct estrogen receptor (ER) subtypes (ERalpha and ERbeta). The present study was undertaken to determine the role of ERbeta in the development of chronic heart failure after experimental myocardial infarction (MI). METHODS AND RESULTS: Female ERbeta null mice (BERKO(Chapel Hill)) and wild-type littermates (WT) were ovariectomized, given 17beta-estradiol, and subjected to chronic anterior MI (MI; BERKO n=31, WT n=30) or sham operation (sham; BERKO n=14, WT n=14). At 8 weeks after MI, both genotypes revealed left ventricular remodeling and impaired contractile function at similar average infarct size (BERKO-MI 32.9+/-5% versus WT-MI 33.0+/-4%); however, BERKO mice showed increased mortality (BERKO-MI 42% versus WT-MI 23%), increased body weight and fluid retention (P<0.01), higher ventricular pro-ANP expression (BERKO-MI 27.9-fold versus sham, WT-MI 5.2-fold versus sham; BERKO-MI versus WT-MI P<0.001), higher atrial natriuretic peptide serum levels, and increased phospholamban expression (P<0.05) compared with WT mice. CONCLUSIONS: Systemic deletion of ERbeta in female mice increases mortality, aggravates clinical and biochemical markers of heart failure, and contributes to impaired expression of Ca(2+)-handling proteins in chronic heart failure after MI. Further studies are required to delineate the relative importance of cardiac and vascular effects of ERbeta and the role of ERalpha in the development of heart failure. [less ▲]

Zur Dynamik der regionalen Variation im Luxemburgischen

in Institut Grand-Ducal, Section de Linguistique, d'Ethnologie et d'Onomastique; Centre National de Littérature (Eds.) Letzebuergesch. Entwicklungstendenzen und Forschungsperspektiven einer jungen Sprache. Beiträge zum Workshop Lëtzebuergesch, November 2001 (2005)

Life in Language Studies in Honour of Wolfgang Kühlwein

Book published by Wissenschaftlicher Verlag Trier (2005)

«Editorial»

in Voir (2005)