References of "2003"
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See detailExplicit formulae for time-space Brownian chaos
Peccati, Giovanni UL

in Bernoulli (2003), 9(1), 25--48

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See detailConstitutional Human Rights and the Commonwealth: An Overview
Happold, Matthew UL; Anderson, Michael

in Anderson, Michael; Happold, Matthew (Eds.) Constitutional Human Rights in the Commonwealth (2003)

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See detailBildung - Kanon - Bildungskanon?
Mein, Georg UL

in Mitteilungen des Deutschen Germanistenverbandes (2003), (4), 534-550

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See detailConstitutional Human Rights in the Commonwealth
Happold, Matthew UL; Anderson, Michael

Book published by British Institute of International and Comparative Law (2003)

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See detailAkt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism
Kortylewski, M.; Feld, F.; Krüger, K. D. et al

in Journal of Biological Chemistry (2003), 278(7), 5242-9

The phosphatidylinositol 3-kinase/Akt pathway plays an important role in the signaling of insulin and other growth factors, which reportedly attenuate the interleukin-6 (IL-6)-mediated stimulation of ... [more ▼]

The phosphatidylinositol 3-kinase/Akt pathway plays an important role in the signaling of insulin and other growth factors, which reportedly attenuate the interleukin-6 (IL-6)-mediated stimulation of acute phase plasma protein genes. We investigated the effect of the protein kinase Akt on IL-6-mediated transcriptional activation. The transient expression of constitutively active Akt inhibited the IL-6-dependent activity of the alpha(2)-macroglobulin promoter in HepG2 cells, whereas expression of an inactive mutant of phosphatidylinositol-dependent kinase 1 had the opposite effect. Since Akt is known to regulate gene expression through inactivation of the transcription factor FKHR (forkhead in rhabdomyosarcoma), we examined the effect of FKHR on STAT3-mediated transcriptional regulation. Indeed, the overexpression of FKHR specifically enhanced the activity of STAT3-dependent promoters but not that of a STAT5-responsive promoter. The effect of FKHR required the presence of functional STAT3 and was abrogated by the expression of dominant negative STAT3 mutants. Furthermore, FKHR and STAT3 were shown to coimmunoprecipitate and to colocalize in the nuclear regions of IL-6-treated HepG2 cells. Our results indicate that FKHR can modulate the IL-6-induced transcriptional activity by acting as a coactivator of STAT3. [less ▲]

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See detailEffets des préretraites sur l'emploi
Sneessens, Henri UL; Pierrard, Olivier; Shadman, Fatemeh

in Revue Française d'Economie (2003), 18(1), 133-155

The paper analyzes the mechanisms by which policies aiming at downsizing the labour force (like early retirement policies) may in fact lead to lower employment levels, even though the equilibrium ... [more ▼]

The paper analyzes the mechanisms by which policies aiming at downsizing the labour force (like early retirement policies) may in fact lead to lower employment levels, even though the equilibrium unemployment rate is decreased. Numerical examples suggest that job losses may be potentially important, even in the case where early retirements are concentrated among groups with high unemployment levels (low-skilled workers). The model takes into account the effects coming from imperfect competition and wage negotiations, as well as those coming from frictions and matching difficulties in an economy with continuous job creations and destructions. Reducing the labour force by promoting early retirement induces in the long run an increase in labour costs, either directly through the effect of unemployment on wages, or indirectly via the effect of unemployment on hiring difficulties. [less ▲]

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See detailSelf-Organization by Optimizing Free-Energy
Verbeek, J. J.; Vlassis, Nikos UL; Kröse, B. J. A.

in Proc. of European Symposium on Artificial Neural Networks (2003)

We present a variational Expectation-Maximization algorithm to learn probabilistic mixture models. The algorithm is similar to Kohonen's Self-Organizing Map algorithm and not limited to Gaussian mixtures ... [more ▼]

We present a variational Expectation-Maximization algorithm to learn probabilistic mixture models. The algorithm is similar to Kohonen's Self-Organizing Map algorithm and not limited to Gaussian mixtures. We maximize the variational free-energy that sums data log-likelihood and Kullback-Leibler divergence between a normalized neighborhood function and the posterior distribution on the components, given data. We illustrate the algorithm with an application on word clustering. [less ▲]

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See detailForschungsprojekt Frühfranzösisch an der Universität des Saarlandes. Code-switching im Sprachunterrricht anhand von Beispielen aus dem Projektcorpus “Effizienz des Frühunterrichts Französisch in saarländischen Schulen“. Wie funktioniert code-switching bei Schülern und Lehrern in der Interaktion im Unterricht?
Ehrhart, Sabine UL

in Zeitschrift für Angewandte Linguistik (2003), 39

Even though the important role of early institutional language teaching has been proved by numerous studies, the practical applications of these findings are still very rare. In the Saarland, one of the ... [more ▼]

Even though the important role of early institutional language teaching has been proved by numerous studies, the practical applications of these findings are still very rare. In the Saarland, one of the German Laender which is situated on the border with France, a pilote project examinates the learning behaviour and mechanism with German primary school children learning French, their neighbouring language, from age 6 on. The author is the coordinator of the scientific team which follows the project from a universitarian point of view. The aim of the paper is to show the important role code-switching plays in this kind of teaching environment and it tries to evaluate its importance by giving examples from different stages of progress during the first two years of learning [less ▲]

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See detailDavid Tyack: Seeking Common Ground. Public Schools in a Diverse Society
Tröhler, Daniel UL

in Zeitschrift für Pädagogische Historiographie (2003), 10

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See detailA comprehensive set of protein complexes in yeast: mining large scale protein-protein interaction screens.
Krause, Roland UL; von Mering, Christian; Bork, Peer

in Bioinformatics (Oxford, England) (2003), 19(15), 1901-8

MOTIVATION: The analysis of protein-protein interactions allows for detailed exploration of the cellular machinery. The biochemical purification of protein complexes followed by identification of ... [more ▼]

MOTIVATION: The analysis of protein-protein interactions allows for detailed exploration of the cellular machinery. The biochemical purification of protein complexes followed by identification of components by mass spectrometry is currently the method, which delivers the most reliable information--albeit that the data sets are still difficult to interpret. Consolidating individual experiments into protein complexes, especially for high-throughput screens, is complicated by many contaminants, the occurrence of proteins in otherwise dissimilar purifications due to functional re-use and technical limitations in the detection. A non-redundant collection of protein complexes from experimental data would be useful for biological interpretation, but manual assembly is tedious and often inconsistent. RESULTS: Here, we introduce a measure to define similarity within collections of purifications and generate a set of minimally redundant, comprehensive complexes using unsupervised clustering. AVAILABILITY: Programs and results are freely available from http://www.bork.embl-heidelberg.de/Docu/purclust/ [less ▲]

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See detailMEDAL: A CASE Tool Extension for Model-driven Software Engineering
Guelfi, Nicolas UL; Ries, Benoît UL; Sterges, Paul UL

in SwSTE'03 IEEE International Conference on Software - Science, Technology & Engineering (2003)

The complexity of today’s software systems leads to the creation of many related diagrams, representing different viewpoints, different levels of abstraction, and different implementation alternatives ... [more ▼]

The complexity of today’s software systems leads to the creation of many related diagrams, representing different viewpoints, different levels of abstraction, and different implementation alternatives. Model-driven software engineering places these models in the center of the development process. Tool support is an essential aspect of model-driven engineering. Of particular interest are model transformation tools: they can facilitate the creation and the evolution of models; they provide a level of traceability between them and they help keeping them synchronized. Unfortunately, currently there are few such tools for UML-based models. This paper presents MEDAL, our model transformation tool. First, we present our viewpoint on model-driven software engineering. Then we describe MEDAL and how we implemented MEDAL on top of Rational XDE. Finally, in the last section we show how a web application development that is based on an architectural framework can be supported by the MEDAL tool. [less ▲]

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See detailLuxemburg
Majerus, Benoît UL

in Hirschfeld, Gerhard; Krumeich, Gerd; Renz, Irina (Eds.) Enzyklopädie Erster Weltkrieg (2003)

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See detailC.7: Luxemburg
Margue, Michel UL; Pauly, Michel UL

in Paravicini, Werner (Ed.) Höfe und Residenzen im spätmittelalterlichen Reich. Ein dynastisch-topographisches Handbuch. (2003)

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See detailFermenta cognitionis. Hannah Arendts Hermeneutik des Nach-Denkens
Mein, Georg UL

in Deutsche Vierteljahrsschrift für Literaturwissenschaft und Geistesgeschichte (2003), 77(3), 481-511

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See detailProtéger les cautions contre elles-mêmes
Prüm, André UL

in Revue de Droit Bancaire et Financier (2003), (5), 269

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See detailMice, microbes and models of infection.
Buer, Jan; Balling, Rudi UL

in Nature Reviews. Genetics (2003), 4(3), 195-205

We urgently need animal models to study infectious disease. Mice are susceptible to a similar range of microbial infections as humans. Marked differences between inbred strains of mice in their response ... [more ▼]

We urgently need animal models to study infectious disease. Mice are susceptible to a similar range of microbial infections as humans. Marked differences between inbred strains of mice in their response to pathogen infection can be exploited to analyse the genetic basis of infections. In addition, the genetic tools that are available in the laboratory mouse, and new techniques to monitor the expression of bacterial genes in vivo, make it the principal experimental animal model for studying mechanisms of infection and immunity. [less ▲]

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See detailMilitary Law in France
Gerkrath, Jörg UL

in European Military Law Systems (2003)

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See detailGeschlechtsspezifische Jugenddelinquenz. Eine Beurteilung der Power-Control Theory
Hadjar, Andreas UL; Baier, Dirk; Boehnke, Klaus

in Mansel, Jürgen; Griese, Hartmut M.; Scherr, Albert (Eds.) Theoriedefizite der Jugendforschung. Standortbestimmung und Perspektiven (2003)

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See detailCity vs. Bits. Von der Beschleunigung der Nachrichten und der Trägheit des Raumes.
Hesse, Markus UL

in Kommune (2003), 21(5), 99-104

Detailed reference viewed: 77 (0 UL)