References of "1992"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailQuestions actuelles en droit allemand des sociétés : de quoi nourrir la réflexion au sein d'un droit belge en mutation
Corbisier, Isabelle UL

in Revue Pratique des Sociétés Civiles et Commerciales (1992), (3), 153-209

Detailed reference viewed: 51 (1 UL)
Peer Reviewed
See detailClinical and laboratory features of type 1 diabetic children at the time of diagnosis
Levy-Marchal, C.; Papoz, L.; De Beaufort, Carine UL et al

in Diabetic Medicine: A Journal of the British Diabetic Association (1992), 9

Detailed reference viewed: 80 (1 UL)
See detailFremdenfeindliche Gewalt: Entwicklung, Strukturen, Eskalationsprozesse
Willems, Helmut UL

in Gruppendynamik (1992), 23. Jg(4), 433-448

Detailed reference viewed: 109 (2 UL)
Peer Reviewed
See detailEnhancement of the Schottky Barrier Height on n-InGaAs by Thin InP Interlayers
Kordoš, P.; Marso, Michel UL; Lüth, H.

in Journal of Electrical Engineering (1992), 44(1992), 367-371

Detailed reference viewed: 39 (1 UL)
Full Text
See detailLogistik – Zauberwort der Raumpolitik
Hesse, Markus UL

in Kommune: Forum für Politik, Ökonomie, Kultur (1992), 10(3), 52-54

Detailed reference viewed: 78 (5 UL)
Peer Reviewed
See detailAnalysis of Subspace Fitting and ML Techniques for Parameter Estimation from Sensor Array Data
Ottersten, Björn UL; Viberg, M.; Kailath, T.

in IEEE Transactions on Signal Processing (1992), SP-40

Detailed reference viewed: 25 (0 UL)
See detailDie historische Bäderarchitektur des Ostseebades Sellin auf Rügen - wertvolles Kapitel für die Entwicklung des Fremdenverkehrs
Helfer, Malte UL

in Greifswalder Beiträge zur Regional-, Freizeit- und Tourismusforschung (1992), 3

Detailed reference viewed: 61 (0 UL)
Peer Reviewed
See detailMultiple Invariance ESPRIT
Swindlehurst, A.; Ottersten, Björn UL; Roy, R. et al

in IEEE Transactions on Signal Processing (1992), SP-40(4), 867881

Detailed reference viewed: 33 (0 UL)
Peer Reviewed
See detailA propos de la taille des villes. Population agglomérée - population dispersée à l'aube du XIXe siècle
Leboutte, René UL

in Le réseau urbain en Belgique dans une perspective historique (1350-1850). Une approche statistique et dynamique (1992)

Detailed reference viewed: 80 (0 UL)
Peer Reviewed
See detailThe molecular and genetic analysis of mouse development.
Gossler, A.; Balling, Rudi UL

in European Journal of Biochemistry (1992), 204(1), 5-11

This review describes some recent advances in the molecular-genetic analysis of mouse development. Reversed genetics and gene assignment have been used to isolate genes affected in developmental mutations ... [more ▼]

This review describes some recent advances in the molecular-genetic analysis of mouse development. Reversed genetics and gene assignment have been used to isolate genes affected in developmental mutations. The establishment of a high-density molecular-genetic map promises to facilitate cloning of additional genes with developmental functions. Based on molecular, biochemical or other biological criteria many mouse genes that code for transcriptional regulators, growth-factor-like molecules and their receptors have been isolated. The role of these genes during development can be analysed in vivo after producing targeted mutations. Mutations can be generated by homologous recombination in the genome of embryonic stem cells and can then be introduced into the mouse germ line by means of germ-line chimaeras. Additional approaches employing stem cells to identify and mutate putative developmental genes are coming into use. [less ▲]

Detailed reference viewed: 93 (0 UL)
Peer Reviewed
See detailDevelopment of the skeletal system.
Balling, Rudi UL; Lau, C. F.; Dietrich, S. et al

in Ciba Foundation Symposium (1992), 165

The analysis of the development of the skeletal system has been greatly facilitated by the availability of a large number of mouse mutants with skeletal defects. Whereas for many of these mutants a ... [more ▼]

The analysis of the development of the skeletal system has been greatly facilitated by the availability of a large number of mouse mutants with skeletal defects. Whereas for many of these mutants a description of the main phenotypic abnormalities is known, molecular insight into the ontogeny of the skeletal system is limited. One of the few skeletal mutants for which the molecular basis is known is undulated. These mice have a defect in the differentiation of the sclerotome and Pax-1, a mouse paired-box containing gene, has been identified as a candidate gene for this mutation. A molecular analysis of three independent undulated alleles revealed that in each case the Pax-1 gene is affected. One of the alleles could be classified as a null allele, in which the Pax-1 gene is deleted. A phenotypic analysis shows that Pax-1 is required for proper differentiation of intervertebral discs and vertebral bodies. [less ▲]

Detailed reference viewed: 163 (0 UL)
Peer Reviewed
See detailPax1, a member of the paired box-containing class of developmental control genes, is mapped to human chromosome 20p11.2 by in situ hybridization (ISH and FISH).
Schnittger, S.; Rao, V. V.; Deutsch, U. et al

in Genomics (1992), 14(3), 740-4

Pax-1, a member of a murine multigene family, belongs to the paired box-containing class of developmental control genes first identified in Drosophila. The Pax-1 gene encodes a sequence-specific DNA ... [more ▼]

Pax-1, a member of a murine multigene family, belongs to the paired box-containing class of developmental control genes first identified in Drosophila. The Pax-1 gene encodes a sequence-specific DNA-binding protein with transcriptional activating properties and has been found to be mutated in the autosomal recessive mutation undulated (un) on mouse chromosome 2 with vertebral anomalies along the entire rostrocaudal axis. By radioactive in situ hybridization (ISH) using a fragment from the murine Pax-1 paired box that is almost identical to the respective sequences from the cognate human gene HuP48 and fluorescence in situ hybridization (FISH) using a complete mouse Pax-1 cDNA, we have assigned the human homologue of murine Pax-1, the PAX1 locus, to chromosome 20p. The map position of PAX1 after FISH (FL-pter value of 0.34 +/- 0.04) corresponds to band p11.2. These results confirm the exceptional homology between human chromosome 20 and the distal segment of mouse chromosome 2, extending from bands F to G, and add PAX1 to the group of genes on 20p like PTPA, PRNP, SCG1, BMP2A, which are located in proximity on both chromosomes. [less ▲]

Detailed reference viewed: 93 (0 UL)
Peer Reviewed
See detailWaardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene.
Tassabehji, M.; Read, A. P.; Newton, V. E. et al

in Nature (1992), 355(6361), 635-6

Waardenburg's syndrome (WS) is an autosomal dominant combination of deafness and pigmentary disturbances, probably caused by defective function of the embryonic neural crest. We have mapped one gene for ... [more ▼]

Waardenburg's syndrome (WS) is an autosomal dominant combination of deafness and pigmentary disturbances, probably caused by defective function of the embryonic neural crest. We have mapped one gene for WS to the distal part of chromosome 2. On the basis of their homologous chromosomal location, their close linkage to an alkaline phosphatase gene, and their related phenotype, we suggested that WS and the mouse mutant Splotch might be homologous. Splotch is caused by mutation in the mouse Pax-3 gene. This gene is one of a family of eight Pax genes known in mice which are involved in regulating embryonic development; each contains a highly conserved transcription control sequence, the paired box. Here we show that some families with WS have mutations in the human homologue of Pax-3. Mutations in a related gene, Pax-6, which, like Pax-3, has both a paired box and a paired-type homeobox sequence, cause the Small-eye mutation in mice and aniridia in man. Thus mutations in the Pax genes are important causes of human developmental defects. [less ▲]

Detailed reference viewed: 165 (1 UL)