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See detailPsychological impact of continuous subcutaneous insulin infusion pump therapy in non-selected newly diagnosed insulin dependent (type 1) diabetic children: Evaluation after two years of therapy [IMPACT PSYCHOLOGIQUE D'UN TRAITEMENT PAR PERFUSION SOUS-CUTANEE CONTINUE D'INSULINE DES LE DIAGNOSTIC CHEZ LES ENFANTS DIABETIQUES NON SELECTIONNES: EVALUATIONS APRES DEUX AND DE TRAITEMENT]
Slijper, F.M.E.; De Beaufort, Carine UL; Bruining, G.J. et al

in Diabete et Metabolisme (1990), 16(4), 273-277

Thirty type 1 (insulin dependent) diabetic children were treated from diagnosis onwards in a random order (using a table of random permutations) with either continous subcutaneous insulin infusion pump ... [more ▼]

Thirty type 1 (insulin dependent) diabetic children were treated from diagnosis onwards in a random order (using a table of random permutations) with either continous subcutaneous insulin infusion pump therapy (CSII), or with conventional injection therapy (CT). After two years of therapy psychosocial measurements were obtained of fifteen CSII children (8 boys, 7 girls; mean age: 12+/-4 years) and thirteen CT children (6 boys, 7 girls; mean age: 10+/-4 years) and their parents. Two families of the CT group refused to participate. The examination consisted of six tests (for the children: junior dutch personality test, WISC-R intelligence test, family relation test, diabetes questionnaire; for the parents: family interaction scale and assessment of acceptance scale). Parents (and pediatricians) rated CSII children higher on compliance and better on metabolic control. Acceptance of diabetes, physical and psychological condition was rated equally by parents and doctors. Except for the diabetes questionnaire, the children of the two groups scored not significantly different. The CSII group expressed significantly less physical complaints and physical restrictions. CSII children showed a tendency to score higher on recalcitrance compared with CT children. How adequate this coping of CSII children may be, is discussed. [less ▲]

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See detailThe Fourth International Workshop on the Standardisation of Insulin Autoantibody Measurement
Kolb, H.; Arnaiz-Villena, A.; De Beaufort, Carine UL et al

in Diabetologia (1990), 33(10), 638-639

[No abstract available]

Detailed reference viewed: 92 (0 UL)
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See detail17 The epidemiology and immunogenetics of IDDM in Italian-heritage populations. Diabetes Epidemiology Research International (DERI) Study Group
Colle, E.; Lounamaa, R.; Tuomilehto, J. et al

in Diabetes/Metabolism Reviews (1990), 6

Detailed reference viewed: 62 (0 UL)
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See detailPsychological impact of continuous subcutaneous insulin infusion pump therapy in non-selected newly diagnosed insulin dependent (type 1) diabetic children: Evaluation after two years of therapy [IMPACT PSYCHOLOGIQUE D'UN TRAITEMENT PAR PERFUSION SOUS-CUTANEE CONTINUE D'INSULINE DES LE DIAGNOSTIC CHEZ LES ENFANTS DIABETIQUES NON SELECTIONNES: EVALUATIONS APRES DEUX AND DE TRAITEMENT]
Slijper, F. M. E.; De Beaufort, Carine UL; Bruining, G. J. et al

in Diabete et Metabolisme (1990), 16(4), 273-277

Thirty type 1 (insulin dependent) diabetic children were treated from diagnosis onwards in a random order (using a table of random permutations) with either continous subcutaneous insulin infusion pump ... [more ▼]

Thirty type 1 (insulin dependent) diabetic children were treated from diagnosis onwards in a random order (using a table of random permutations) with either continous subcutaneous insulin infusion pump therapy (CSII), or with conventional injection therapy (CT). After two years of therapy psychosocial measurements were obtained of fifteen CSII children (8 boys, 7 girls; mean age: 12+/-4 years) and thirteen CT children (6 boys, 7 girls; mean age: 10+/-4 years) and their parents. Two families of the CT group refused to participate. The examination consisted of six tests (for the children: junior dutch personality test, WISC-R intelligence test, family relation test, diabetes questionnaire; for the parents: family interaction scale and assessment of acceptance scale). Parents (and pediatricians) rated CSII children higher on compliance and better on metabolic control. Acceptance of diabetes, physical and psychological condition was rated equally by parents and doctors. Except for the diabetes questionnaire, the children of the two groups scored not significantly different. The CSII group expressed significantly less physical complaints and physical restrictions. CSII children showed a tendency to score higher on recalcitrance compared with CT children. How adequate this coping of CSII children may be, is discussed. [less ▲]

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See detailIncidence of juvenile type 1 (insulin dependent) diabetes mellitus in France
Levy-Marchal, C.; Papoz, L.; De Beaufort, Carine UL et al

in Diabetologia (1990), 33

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See detailA process specification formalism
Mauw, Sjouke UL; Veltink, G. J.

in Fundamenta Informaticae (1990), XIII

Detailed reference viewed: 64 (1 UL)
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See detailHypertensive Herzkrankheit - pathophysiologische Grundlaten, Diagnostik und Therapie
Neyses, Ludwig UL; Vetter, H

in Deutsche Medizinische Wochenschrift (1946) (1990), (39), 1480-1486

Detailed reference viewed: 68 (0 UL)
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See detail[Hypertensive heart disease. Pathophysiological foundation, diagnosis and therapy].
Neyses, Ludwig UL; Vetter, H.

in Deutsche medizinische Wochenschrift (1946) (1990), 115(39), 1480-6

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See detail[Disturbed endothelium-dependent blood vessel relaxation in essential hypertension].
Neyses, Ludwig UL; Vetter, H.

in Deutsche medizinische Wochenschrift (1946) (1990), 115(51-52), 1981

Detailed reference viewed: 47 (0 UL)
See detail1919: Quel avenir pour la monarchie?
Scuto, Denis UL

in Muller, Jean-Claude (Ed.) 100 Joer Lëtzebuerger Dynastie : collections et souvenirs de la Maison grand-ducale. Catalogue de l’exposition au Musée national d’histoire et d’art, (1990)

Detailed reference viewed: 73 (3 UL)
See detailSinnwelt Freizeit Jugendliche zwischen Märkten und Verbänden
Eckert, Roland; Drieseberg, Thomas; Willems, Helmut UL

Book published by Leske + Budrich (1990)

Detailed reference viewed: 42 (1 UL)
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See detailGewaltberichte aus Großbritannien Vorschläge der in Großbritannien eingesetzten Untersuchungskommissionen zur Verhinderung oder Begrenzung ethnisch begründeter Konflikte
Willems, Helmut UL; Eckert, Roland; Wolf, Marianne

in Schwind, Hans-Dieter; Baumann, Jürgen; u.a. (Eds.) Ursachen, Prävention und Kontrolle von Gewalt. Analysen und Vorschläge der Unabhängigen Regierungskommission zur Verhinderung und Bekämpfung von Gewalt (Gewaltkommission), III (1990)

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See detailPosition-specific activity of the Hox1.1 promoter in transgenic mice.
Puschel, A. W.; Balling, Rudi UL; Gruss, P.

in Development (1990), 108(3), 435-42

During development, positional values have to be assigned to groups of cells. The murine Hox genes are a class of genes that are predicted to be involved at some stage in this process. During ... [more ▼]

During development, positional values have to be assigned to groups of cells. The murine Hox genes are a class of genes that are predicted to be involved at some stage in this process. During embryogenesis they are expressed in distinct overlapping region- and stage-specific patterns and therefore must be regulated in response to positional information. In this study, we have analysed the activity of Hox1.1 promoter sequences in transgenic mice. The use of lacZ as a marker allows a detailed analysis of expression at the single cell level during early embryonic development. We show that 3.6 kbp of promoter and 1.7 kbp of 3' sequences provide sufficient regulatory information to express a transgene in a spatial and temporal manner indistinguishable from the endogenous Hox1.1 gene during the period of development when Hox1.1 expression is established. The activation occurs in a strict order in specific ectodermal and mesodermal domains. Within each of these domains the transgene is activated over a period of four hours apparently randomly in single cells. In a following second period, Hox1.1 and transgene expression patterns diverge. In this period, transgene expression persists in many mesodermally derived cells that do not express Hox1.1 indicating the absence of a negative regulatory element in the transgene. The anterior boundary of transgene expression is identical to that of Hox1.1. However, no posterior boundary of transgene expression is set, suggesting that a separate element absent from the transgene specifies this boundary. [less ▲]

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See detailFrom the structure to the function of villin, an actin-binding protein of the brush border.
Friederich, Evelyne UL; Pringault, E.; Arpin, M. et al

in BioEssays (1990), 12(9), 403-8

Villin, a calcium-regulated actin-binding protein, modulates the structure and assembly of actin filaments in vitro. It is organized into three domains, the first two of which are homologous. Villin is ... [more ▼]

Villin, a calcium-regulated actin-binding protein, modulates the structure and assembly of actin filaments in vitro. It is organized into three domains, the first two of which are homologous. Villin is mainly produced in epithelial cells that develop a brush border and which are responsible for nutrient uptake. Expression of the villin structural gene is precisely regulated during mouse embryogenesis and is restricted in adults, to certain epithelia of the gastrointestinal and urogenital tracts. The function of villin has been assessed by transfecting CV1 cells with a human cDNA encoding wild-type villin or mutant villin. Synthesis of large amounts of villin in cells which do not normally produce this protein induces the growth of microvilli on the cell surface and the redistribution of F-actin, concomitant with the disappearance of stress fibers. The complete villin sequence is required for the morphogenic effect. These results suggest that villin plays a key role in the morphogenesis of microvilli. [less ▲]

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See detailIsolated myocardial cells: a new tool for the investigation of hypertensive heart disease.
Neyses, Ludwig UL; Vetter, H.

in Journal of Hypertension. Supplement) (1990), 8(4), 99-102

Cardiac hypertrophy is characterized by marked abnormalities in the contraction/relaxation pattern of the heart. For example, delayed relaxation is a prominent feature, impairing ventricular filling and ... [more ▼]

Cardiac hypertrophy is characterized by marked abnormalities in the contraction/relaxation pattern of the heart. For example, delayed relaxation is a prominent feature, impairing ventricular filling and coronary flow. In intact heart preparations the relative contribution of fibrosis and of the myocardial cell itself to these abnormalities cannot be correctly assessed. Biochemical studies on the mechanisms of impaired contraction and relaxation and hypertensive heart failure are hampered by the fact that 75% of all heart cells are non-myocytes. We therefore established the model of the isolated calcium-tolerant, adult rat cardiomyocyte as a new approach to the investigation of these problems. Contractility was measured using a videomicroscope system with high time resolution (1 ms). Angiotensin II induced a marked relaxation delay in the cardiomyocyte from normotensive rats and showed a moderate positive inotropic effect, whereas isoproterenol had a strong positive inotropic effect but accelerated relaxation. Therefore, angiotensin II is capable of inducing a relaxation delay even in the absence of coronary ischaemia or hypertension. These first results show that the isolated cardiomyocyte model may be a useful approach to investigating the mechanisms of hypertensive heart disease. [less ▲]

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See detailKrichever-Novikov algebras for more than two points
Schlichenmaier, Martin UL

in Letters in Mathematical Physics (1990), 19(2), 151--165

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See detailA pertussis toxin-sensitive G protein is required to induce histamine release from rat peritoneal mast cells by bradykinin
Bueb, Jean-Luc UL; Mousli, M.; Landry, Y. et al

in Agents and Actions (1990), 30(1-2), 98-101

Bradykinin, kallidin (Lys-bradykinin) and [Thi 5,8, D-Phe7]-bradykinin, a functional B2 antagonist, induce histamine release from rat peritoneal mast cells. The histamine release is dependent upon added ... [more ▼]

Bradykinin, kallidin (Lys-bradykinin) and [Thi 5,8, D-Phe7]-bradykinin, a functional B2 antagonist, induce histamine release from rat peritoneal mast cells. The histamine release is dependent upon added calcium when mast cells are placed in calcium-free medium 30 min before being triggered with the kinins. Histamine release was dose-dependently inhibited by pertussis toxin (1-100 ng/ml) and by benzalkonium chloride (0.1-3 micrograms/ml). The efficiency of ionophore A23187 on histamine release was affected neither by pertussis toxin nor by benzalkonium chloride. The parallel response of rat peritoneal mast cells to kinins and to substance P suggest that these peptides have the same mechanisms of action i.e. activation of a pertussis toxin-sensitive G protein and of phospholipase C defining a peptidergic triggering pathway of mast cells. [less ▲]

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See detailDirection-of-Arrival Estimation for Wide-Band Signals Using the ESPRIT Algorithm
Ottersten, Björn UL; Kailath, T.

in IEEE Transactions on Acoustics, Speech, and Signal Processing (1990), ASSP-38(2), 317327

Detailed reference viewed: 30 (0 UL)