References of "1987"
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See detailLow-Noise Bulk Unipolar Devices in Si and GaAs
Beneking, H.; Cloos, J.-M.; Fernholz, G. et al

in Proceedings of the 17th European Solid State Devices Research Conference, Bologna, Italy (1987)

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See detailEinfluss von oraler Volumenbelastung, Herzfrequenz und Reserpin auf die Sekretion von atrialem natriuretischen Peptid beim Menschen
Neyses, Ludwig UL; Nitsch, J; Heinrichs, S et al

in Kreye, V; Bussmann, W (Eds.) Atriales natriurestisches Peptid und das kardiovaskulaere System (1987)

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See detailThe effect of carrageenan-induced inflammation on the sensitivity of unmyelinated skin nociceptors in rat
Kocher, Laurence; Anton, Fernand UL; Reeh, Peter-Werner et al

in Pain (1987), 29(3), 363-373

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See detailDischarge patterns of afferent cutaneous nerve fibers from the rat's tail during prolonged noxious mechanical stimulation
Handwerker, Hermann-Otto; Anton, Fernand UL; Reeh, Peter-Werner

in Experimental Brain Research (1987), 65(3), 493-504

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See detailInhibition of flecainide absorption by activated charcoal.
Nitsch, J.; Kohler, U.; Neyses, Ludwig UL et al

in The American journal of cardiology (1987), 60(8), 753

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See detail[Resuscitation of a 36-year-old patient with a short PQ time and a history of Hodgkin's disease].
Neyses, Ludwig UL; Nitsch, J.; Manz, M. et al

in Der Internist (1987), 28(3), 196-9

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See detailDifferences between neurons in the cat`s thalamic ventroposterolateral nucleus (VPL) and its ventral periphery (VPLvp): a morphometric analysis
Hanesch, Ulrike UL; Haumann, Petra; Kniffki, Klaus-Dietrich et al

in Neuroscience (1987), 22

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See detailNonequilibrium Phase Transitions in Solid Catalysts for Oxidation
Greger, Manfred UL; Riekert, Lothar

in Berichte der Bunsengesellschaft für physikalische Chemie (1987), 91

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See detail[Elevated plasma flecainide concentrations in heart failure].
Nitsch, J.; Neyses, Ludwig UL; Kohler, U. et al

in Deutsche medizinische Wochenschrift (1946) (1987), 112(44), 1698-700

In 42 patients with heart failure who were on long-term treatment with flecainide (2 X 100 mg daily by mouth) plasma concentration of flecainide was measured before the morning dose and compared with the ... [more ▼]

In 42 patients with heart failure who were on long-term treatment with flecainide (2 X 100 mg daily by mouth) plasma concentration of flecainide was measured before the morning dose and compared with the clinical grade of heart failure or left ventricular ejection fraction (in the levo-angiogram). Mean plasma flecainide concentration was 415 +/- 244 ng/ml (110-1035 ng/ml), mean ejection fraction 55 +/- 17.7% (24-84%) (r = -0.60). In seven patients with plasma concentrations over 700 ng/ml (870 +/- 150 ng/ml) in clinical grade III or IV, ejection fractions were 24, 25, 25, 30, 33, 37 and 44%, respectively. In two patients (ejection fraction of 24 and 25%, respectively) the morning plasma concentration was around 1000 ng/ml. The results point to possible high plasma flecainide concentrations--at times in the toxic range--in patients who are in heart failure. In patients with marked reduction in left ventricular pumping function who are on long-term flecainide treatment, a reduction in dosage or monitoring of plasma flecainide concentration is indicated. [less ▲]

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See detailContinuous subcutaneous insulin infusion in children
De Beaufort, Carine UL; Bruining, G. J.

in Diabetic Medicine: A Journal of the British Diabetic Association (1987), 4(2), 103-108

Insulin-dependent diabetes mellitus usually presents in childhood. Since it is generally accepted that persisting metabolic derangements contribute to the development of micro- and macrovascular ... [more ▼]

Insulin-dependent diabetes mellitus usually presents in childhood. Since it is generally accepted that persisting metabolic derangements contribute to the development of micro- and macrovascular complications, a primary aim of the management of children with diabetes is to achieve near normalization of metabolism. In adults continuous subcutaneous insulin infusion (CSII) has been used to optimize control. Despite a reluctance amongst paediatricians to use CSII in children, several studies with pumps have been performed in adolescents. The results of these studies are contradictory with respect to acceptability and achieved metabolic control. Thus, some authors report a near normalization of blood glucose concentrations, whereas others only find a temporary improvement. Patient selection seems to account for many of these differences. This suggests that methods ought to be developed to predict success or failure of CSII in a particular adolescent patient. For diabetic toddlers with their age-specific problems CSII may be a therapy of choice. So far, good acceptability and improved metabolic control are reported in this group. More studies are needed to confirm this. It is important that the diabetic clinic as well as the patient is organized to a high standard before starting CSII. Home blood glucose measurements, education, and a 24-h telephone service are essential factors for the management of diabetic children, treated conventionally or with CSII. [less ▲]

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See detailAntibodies to a 64,000 M(r) human islet cell antigen precede the clinical onset of insulin-dependent diabetes
Baekkeskov, S.; Landin, M.; Kristensen, J. K. et al

in Journal of Clinical Investigation (1987), 79(3), 926-934

Antibodies in sera from newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients are directed to a human islet cell protein of relative molecular mass (M(r)) 64,000. Since IDDM seems to develop ... [more ▼]

Antibodies in sera from newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients are directed to a human islet cell protein of relative molecular mass (M(r)) 64,000. Since IDDM seems to develop after a prodromal period of β-cell autoimmunity,, this study has examined whether 64,000 M(r) antibodies could be detected in 14 individuals who subsequently developed IDDM and five first degree relatives who have indications of altered β-cell function. Sera were screened by immunoprecipitation on total detergent lysates of human islets and positive sera retested on membrane protein preparations. Antibodies to the 64,000 M(r) membrane protein were consistently detected in 11/14 IDDM patients, and in all 5 first degree relatives. 10 IDDM patients were already positive in the first samples, obtained 4-91 mo before the clinical onset of IDDM, whereas 1 patient progressed to a high 64,000 M(r) immunoreactivity, at a time where a commencement of a decline in β-cell function was detected. 64,000 M(r) antibodies were detected before islet cell cytoplasmic antibodies (ICCA) in two patients. In the control groups of 21 healthy individuals, 36 patients with diseases of the thyroid and 5 SLE patients, the 64,000 M(r) antibodies were detected in only one individual, who was a healthy sibling to an IDDM patient. These results suggest that antibodies against the M(r) 64,000 human islet protein are an early marker of β-cell autoimmunity and may be useful to predict a later development of IDDM. [less ▲]

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See detailErfahrungen von Gewalt bei jungen Polizeibeamten - Überlegungen zum Problem der Eskalation
Willems, Helmut UL; Eckert, Roland

in Der ethnische Aspekt des Gewaltproblems. Seminarbericht (1987)

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See detailYouth Protest in Switzerland, the Netherlands and Germany
Willems, Helmut UL; Eckert, Roland

in Nasr, Salim; Hanf, Theodor (Eds.) Urban Crisis and Social Movements - Arab and European Perspectives (1987)

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See detailQuantitative sensory examination in diabetic children: Assessment of thermal discrimination
Heimans, J. J.; Bertelsmann, F. W.; De Beaufort, Carine UL et al

in Diabetic Medicine: A Journal of the British Diabetic Association (1987), 4(3), 251-253

Vibration perception thresholds (VPTs) and thermal discrimination thresholds (TDTs) were investigated in 55 insulin-dependent diabetic children aged 11.3 ± 3.9 years (mean ± SD) and in 81 controls. There ... [more ▼]

Vibration perception thresholds (VPTs) and thermal discrimination thresholds (TDTs) were investigated in 55 insulin-dependent diabetic children aged 11.3 ± 3.9 years (mean ± SD) and in 81 controls. There was no significant difference in VPTs between the two groups. TDTs were significantly higher in the group of diabetic children (p < 0.03). Eight diabetic children had abnormal thermal sensation and one child had abnormal vibratory sensation. TDT correlated positively with duration of diabetes mellitus (r = 0.25; p < 0.05). Both investigations can be carried out easily and are unobtrusive, which is an important advantage in the examination of children. [less ▲]

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