![]() ; ; et al in Computer Applications in the Biosciences [=CABIOS] (1997), 13(4), 481-483 Detailed reference viewed: 122 (1 UL)![]() ![]() Schneider, Reinhard ![]() in Nucleic Acids Research (1997), 25(1), 226-230 HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment ... [more ▼] HSSP is a derived database merging structural (3-D) and sequence (1-D) information. For each protein of known 3-D structure from the Protein Data Bank (PDB), the database has a multiple sequence alignment of all available homologues and a sequence profile characteristic of the family. The list of homologues is the result of a database search in SwissProt using a position-weighted dynamic programming method for sequence profile alignment (MaxHom). The database is updated frequently. The listed homologues are very likely to have the same 3-D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of aligned sequence families, but also a database of implied secondary and tertiary structures covering 29% of all SwissProt-stored sequences. [less ▲] Detailed reference viewed: 128 (0 UL) |
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