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ORBilu is a project developed by
   Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge; ; et al in npj Digital Medicine (2021), 4(53), Consumer wearables and sensors are a rich source of data about patients’ daily disease and symptom burden, particularly in the case of movement disorders like Parkinson’s Disease (PD). However ... [more ▼] Consumer wearables and sensors are a rich source of data about patients’ daily disease and symptom burden, particularly in the case of movement disorders like Parkinson’s Disease (PD). However, interpreting these complex data into so-called digital biomarkers requires complicated analytical approaches, and validating these biomarkers requires sufficient data and unbiased evaluation methods. Here we describe the use of crowdsourcing to specifically evaluate and benchmark features derived from accelerometer and gyroscope data in two different datasets to predict the presence of PD and severity of three PD symptoms: tremor, dyskinesia and bradykinesia. Forty teams from around the world submitted features, and achieved drastically improved predictive performance for PD status (best AUROC=0.87), as well as tremor- (best AUPR=0.75), dyskinesia- (best AUPR=0.48) and bradykinesia-severity (best AUPR=0.95). [less ▲] Detailed reference viewed: 125 (17 UL)The finite index basis property; ; et al in Journal of Pure and Applied Algebra (2015) We describe in this paper a connection between bifix codes, symbolic dynamical systems and free groups. This is in the spirit of the connection established previously for the symbolic systems ... [more ▼] We describe in this paper a connection between bifix codes, symbolic dynamical systems and free groups. This is in the spirit of the connection established previously for the symbolic systems corresponding to Sturmian words. We introduce a class of sets of factors of an infinite word with linear factor complexity containing Sturmian sets and regular interval exchange sets, namely the class of tree sets. We prove as a main result that for a uniformly recurrent tree set S, a finite bifix code X on the alphabet A is S-maximal of S-degree d if and only if it is the basis of a subgroup of index d of the free group on A [less ▲] Detailed reference viewed: 104 (4 UL) |
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