References of "Peliti, Luca"
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See detailThermodynamics of accuracy in kinetic proofreading: dissipation and efficiency trade-offs
Rao, Riccardo UL; Peliti, Luca

in Journal of Statistical Mechanics: Theory and Experiment (2015)

The high accuracy exhibited by biological information transcription processes is due to kinetic proofreading, i.e. by a mechanism which reduces the error rate of the information-handling process by ... [more ▼]

The high accuracy exhibited by biological information transcription processes is due to kinetic proofreading, i.e. by a mechanism which reduces the error rate of the information-handling process by driving it out of equilibrium. We provide a consistent thermodynamic description of enzyme-assisted assembly processes involving competing substrates, in a master equation framework. We introduce and evaluate a measure of the efficiency based on rigorous non- equilibrium inequalities. The performance of several proofreading models are thus analyzed and the related time, dissipation and efficiency versus error trade-offs exhibited for different discrimination regimes. We finally introduce and analyse in the same framework a simple model which takes into account correlations between consecutive enzyme-assisted assembly steps. This work highlights the relevance of the distinction between energetic and kinetic discrimination regimes in enzyme-substrate interactions. [less ▲]

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See detailEntropy production in quantum Brownian motion
Pucci, Lorenzo; Esposito, Massimiliano UL; Peliti, Luca

in Journal of Statistical Mechanics: Theory and Experiment (2013), P04005

We investigate how to coherently define entropy production for a process of transient relaxation in the quantum Brownian motion model for the harmonic potential. We compare a form, referred to as ‘poised’ ... [more ▼]

We investigate how to coherently define entropy production for a process of transient relaxation in the quantum Brownian motion model for the harmonic potential. We compare a form, referred to as ‘poised’ (P), which after non-Markovian transients corresponds to a definition of heat as the change in the system Hamiltonian of mean force, with a recent proposal by Esposito et al (ELB) based on a definition of heat as the energy change in the bath. Both expressions yield a positive-definite entropy production and they coincide for vanishing coupling strength, but their difference is proved to be always positive (after non-Markovian transients disappear) and to grow as the coupling strength increases. In the classical ver-damped limit the ‘poised’ entropy production converges to the entropy production used in stochastic thermodynamics. We also investigate the effects of the system size, and of the ensuing Poincar´e recurrences, and how the classical limit is approached. We close by discussing the strongcoupling limit, in which the ideal canonical equilibrium of the bath is violated. [less ▲]

Detailed reference viewed: 154 (6 UL)