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   CaSiAn: a Calcium Signaling Analyzer toolMoein, Mahsa  ; Grzyb, Kamil ; et alin Bioinformatics (2018), 1 Ca2þ is a central second messenger in eukaryotic cells that regulates many cellular proc- esses. Recently, we have indicated that typical Ca2þ signals are not purely oscillatory as widely assumed, but ... [more ▼] Ca2þ is a central second messenger in eukaryotic cells that regulates many cellular proc- esses. Recently, we have indicated that typical Ca2þ signals are not purely oscillatory as widely assumed, but exhibit stochastic spiking with cell type and pathway specific characteristics. Here, we present the Calcium Signaling Analyzer (CaSiAn), an open source software tool that allows for quantifying these signal characteristics including individual spike properties and time course statis- tics in a semi-automated manner. CaSiAn provides an intuitive graphical user interface allowing experimentalists to easily process a large amount of Ca2þ signals, interactively tune peak detection, revise statistical measures and access the quantified signal properties as excel or text files. [less ▲] Detailed reference viewed: 161 (16 UL)On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling; Moein, Mahsa ; et alin Chaos (2018), 28(4), 045115 Detailed reference viewed: 192 (16 UL) Dissecting the crosstalk between intracellular calcium signalling and mitochondrial metabolismMoein, Mahsa Doctoral thesis (2017) Detailed reference viewed: 114 (23 UL)Multiscale Modeling Indicates That Temperature Dependent [Ca2+]i Spiking in Astrocytes Is Quantitatively Consistent with Modulated SERCA ActivityKomin, Niko ; Moein, Mahsa ; et alin Neural Plasticity (2015), Volume 2015 Detailed reference viewed: 215 (26 UL)Classifying Ear Disorders Using Support Vector MachinesMoein, Mahsa ; ; et alin IEEE (2010, September), 1 Detailed reference viewed: 129 (4 UL)Iris Disease Classifying Using Neuro-Fuzzy Medical Diagnosis Machine; ; Moein, Mahsa in Advances in Intelligent and Soft Computing (2009), 56 Detailed reference viewed: 121 (0 UL) |
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