References of "Lehrach, Hans"
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See detailData and knowledge management in translational research: implementation of the eTRIKS platform for the IMI OncoTrack consortium
Gu, Wei UL; Yildirimman, Reha; Van der Stuyft, Emmanuel et al

in BMC Bioinformatics (2019), 20(1), 164

For large international research consortia, such as those funded by the European Union’s Horizon 2020 programme or the Innovative Medicines Initiative, good data coordination practices and tools are ... [more ▼]

For large international research consortia, such as those funded by the European Union’s Horizon 2020 programme or the Innovative Medicines Initiative, good data coordination practices and tools are essential for the successful collection, organization and analysis of the resulting data. Research consortia are attempting ever more ambitious science to better understand disease, by leveraging technologies such as whole genome sequencing, proteomics, patient-derived biological models and computer-based systems biology simulations. [less ▲]

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See detailControlling complexity: the clinical relevance of mouse complex genetics.
Schughart, Klaus; Libert, Claude; Kas, Martien J. et al

in European Journal of Human Genetics (2013), 21(11), 1191-6

Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries ... [more ▼]

Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches. [less ▲]

Detailed reference viewed: 137 (3 UL)