References of "Kumsta, Robert 50043977"
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See detailUrbanicity, behavior problems and HPA axis regulation in preschoolers
Effenberger, Pauline; Send, Tabea; Gilles, Maria et al

in Psychoneuroendocrinology (in press)

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See detailLess efficient cognitive pain modulation in healthy older adults – the impact of executive functions, chronic stress, and physical activity
Heiler, Ann-Sophie; van der Meulen, Marian UL; Miltner, Wolfgang et al

in Heinrichs, Markus; Schönauer, Monika (Eds.) 47. Jahrestagung Psychologie und Gehirn (2022)

Demographic change and the associated increasing prevalence of chronic pain have contributed to increased research interest in the field of aging. Aging has been associated with less efficient pain ... [more ▼]

Demographic change and the associated increasing prevalence of chronic pain have contributed to increased research interest in the field of aging. Aging has been associated with less efficient pain inhibition through cognitive distraction. As pain modulation and executive functioning mainly involve the prefrontal cortical network, which shows age-related atrophy, we hypothesized an association between deteriorating cognitive modulation of pain in healthy older adults and reduced executive functions. As chronic stress can decrease executive functioning through prefrontal cortical impairment, we expected a negative impact on distraction from pain. In contrast, physical activity can have a stress-buffering effect and positively influences executive functions in older age. Therefore, increased physical activity should lead to better distraction from pain. Healthy young (18 -30 years) and older adults (65+ years) took part in a pain distraction paradigm (N-back) while receiving non-painful and moderately painful electric stimuli. Before, we examined executive functions, including response inhibition (Go/No-Go-task), inhibitory control (Stroop task), and working memory (Sternberg task). Additionally, chronic stress and physical activity were assessed using self-report questionnaires, supported by physiological measurements (heart rate variability). Preliminary results indicate a negative impact of chronic stress on distraction from pain particular in young participants, while physical fitness was related to more successful pain modulation in older adults. Our final results will contribute to a more differentiated view on executive functioning and pain modulation in aging, thereby leading to a better understanding of the impact of aging on non-pharmacological pain treatment and to better adapted pain therapies in this population. [less ▲]

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See detailPrenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood
Mattonet, Katharina; Nowack-Weyers, Nikola; Vogel, Vanessa et al

in Epigenetics (2022), 17(9), 935-952

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See detailGenes in treatment: Polygenic risk scores for different psychopathologies, neuroticism, educational attainment and IQ and the outcome of two different exposure-based fear treatments
Wannemüller, Andre; Kumsta, Robert UL; Jöhren, Hans-Peter et al

in World Journal of Biological Psychiatry (2021)

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See detailThe brain under stress—A systematic review and activation likelihood estimation meta-analysis of changes in BOLD signal associated with acute stress exposure
Berretz, G.; Packheiser, J.; Kumsta, Robert UL et al

in Neuroscience and Biobehavioral Reviews (2021), 124

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See detailPolygenic scores for handedness and their association with asymmetries in brain structure
Ocklenburg, Sebastian; Metzen, Dorothea; Schlüter, Caroline et al

in Brain Structure and Function (2021)

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See detailPolygenic Scores for Cognitive Abilities and Their Association with Different Aspects of General Intelligence—A Deep Phenotyping Approach
Genç, E.; Schlüter, C.; Fraenz, C. et al

in Molecular Neurobiology (2021)

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See detailExploring hair steroid concentrations in asylum seekers, internally displaced refugees, and immigrants
Buchmüller, T.; Lembcke, H.; Busch, J. et al

in Stress (2020), 23(5), 538-545

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See detailHighs and lows: Genetic susceptibility to daily events
Sicorello, M.; Dieckmann, L.; Moser, D. et al

in PLoS ONE (2020), 15(8 August),

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See detailGenetik und Epigenetik in der Psychotherapie von Depression und Angststörungen
Schaumburg, S.; Schneider, S.; Margraf, J. et al

in Verhaltenstherapie (2020), 30(1), 58-67

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See detailThe role of the 5-HTTLPR polymorphism in acquired capability for suicide
Wannemueller, A.; Forkmann, T.; Glaesmer, H. et al

in Suicide and Life-Threatening Behavior (2020), 50(6), 1121-1126

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See detailThe mediating role of KITLG DNA methylation in the association between childhood adversity and cortisol stress reactivity does not replicate in monocytes
Frach, L.; Tierling, S.; Schwaiger, M. et al

in Psychoneuroendocrinology (2020), 116

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See detailAdoptees' responses to separation from, and reunion with, their adoptive parent at age 4 years is associated with long-term persistence of autism symptoms following early severe institutional deprivation
Sonuga-Barke, E.; Kennedy, M.; Golm, D. et al

in Development and Psychopathology (2020), 32(2), 631-640

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See detailAngiotensin involvement in trauma processing—exploring candidate neurocognitive mechanisms of preventing post-traumatic stress symptoms
Shkreli, L.; Woud, M. L.; Ramsbottom, R. et al

in Neuropsychopharmacology (2020), 45(3), 507-514

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See detailWhy does early childhood deprivation increase the risk for depression and anxiety in adulthood? A developmental cascade model
Golm, D.; Maughan, B.; Barker, E. D. et al

in Journal of Child Psychology and Psychiatry and Allied Disciplines (2020), 61(9), 1043-1053

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See detailTargeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage
Moser, D. A.; Müller, S.; Hummel, E. M. et al

in Psychoneuroendocrinology (2020), 120

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See detailEarly childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment
Mackes, N. K.; Golm, D.; Sarkar, S. et al

in Proceedings of the National Academy of Sciences of the United States of America (2020), 117(1), 641-649

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See detailEvent-related functional MRI of awake behaving pigeons at 7T
Behroozi, M.; Helluy, X.; Ströckens, F. et al

in Nature Communications (2020), 11(1),

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