References of "Schulz, André 50003056"
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See detailInteroception and Stress
Schulz, André UL; Vögele, Claus UL

in Frontiers in Psychology (2015), 6(1), 993

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See detailZentralnervöse Verarbeitung von Körpersignalen bei Anorexia nervosa
Lutz, Annika UL; Schulz, André UL; Voderholzer, Ulrich et al

Scientific Conference (2015, April)

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See detailTwo separable mechanisms are responsible for mental stress effects on high frequency heart rate variability: an intra-individual approach in a healthy and a diabetic sample
Kuehl, L. K.; Deuter, C. E.; Richter, S. et al

in International Journal of Psychophysiology (2015), 95(3), 299-303

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See detailInteroception
Schulz, André UL

in Wright, J. D. (Ed.) International Encyclopedia of the Social and Behavioral Sciences (2015)

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See detailCortical representation of afferent bodily signals in borderline personality disorder: neural correlates and raltionship to emotional dysregulation
Müller, L. E.; Schulz, André UL; Andermann, M. et al

in JAMA Psychiatry (2015), 72(11), 1077-1086

The ability to perceive and regulate one's own emotions has been tightly linked to the processing of afferent bodily signals (interoception). Thus, disturbed interoception might contribute to the core ... [more ▼]

The ability to perceive and regulate one's own emotions has been tightly linked to the processing of afferent bodily signals (interoception). Thus, disturbed interoception might contribute to the core feature of emotional dysregulation in borderline personality disorder (BPD), as increased levels of depersonalization, body image disturbances, and reduced sensitivity to physical pain suggest poor body awareness in BPD. OBJECTIVE: To determine neural correlates of disturbed body awareness in BPD and its associations with emotional dysregulation and to explore improvements in body awareness with BPD symptom remission. DESIGN, SETTING, AND PARTICIPANTS: Case-control study performed at Heidelberg University Hospital, Heidelberg, Germany. Heartbeat evoked potentials (HEPs), an indicator of the cortical representation of afferent signals from the cardiovascular system, were investigated in 34 medication-free patients with BPD, 31 healthy volunteers, and 17 medication-free patients with BPD in remission. The HEPs were assessed using 5-minute resting-state electroencephalograms and parallel electrocardiograms. Core BPD symptoms, history of childhood traumatization, and psychiatric disorders were assessed by means of self-reports and structured interviews. To measure neural correlates of disturbed body awareness, high-resolution T1-weighted structural magnetic resonance imaging scans were collected and analyzed using voxel-based morphometry and region-of-interest-based approaches. The study was performed between 2012 and 2014, and data analysis was performed in 2014. MAIN OUTCOMES AND MEASURES: Mean HEP amplitudes in resting-state electroencephalograms and their correlation with self-reported emotional dysregulation, as well as with gray matter volume. RESULTS: Patients with BPD had significantly reduced mean HEP amplitudes compared with healthy volunteers (F1,61 = 11.32, P = .001), whereas the mean HEP amplitudes of patients with BDP in remission lie somewhere in between these 2 groups of participants (P > .05). The HEP amplitudes were negatively correlated with emotional dysregulation (R = -0.30, P = .01) and positively associated with gray matter volume in the left anterior insula (R = 0.53, P < .05) and the bilateral dorsal anterior cingulate cortex (R = 0.47, P < .05), 2 structures that have been identified as core regions for interoception. CONCLUSIONS AND RELEVANCE: The results indicate state-dependent deficits in the cortical processing of bodily signals in patients with BPD, which appear to be associated with core features of BPD. The analysis of patients with BPD in remission suggests an improvement in cortical representation of bodily signals with symptom remission. Results recommend the integration of techniques to strengthen bodily awareness in psychotherapeutic interventions of BPD. [less ▲]

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See detailAltered patterns of heartbeat-evoked potentials in depersonalization/derealization disorder: neurophysiological evidence for impaired cortical representation of bodily signals
Schulz, André UL; Köster, S.; Beutel, M. E. et al

in Psychosomatic Medicine (2015), 77(5), 506-516

OBJECTIVE: Core features of depersonalization-/derealization disorder (DPD) are emotional numbing and feelings of disembodiment. While there are several neurophysiological findings supporting subjective ... [more ▼]

OBJECTIVE: Core features of depersonalization-/derealization disorder (DPD) are emotional numbing and feelings of disembodiment. While there are several neurophysiological findings supporting subjective emotional numbing, the psychobiology of disembodiment remains unclear. METHODS: Heartbeat-evoked potentials (HEPs), which are considered psychophysiological indicators for the cortical representation of afferent signals originating from the cardiovascular system, were assessed in 23 patients with DPD and 24 healthy control individuals during rest and while performing a heartbeat perception task. RESULTS: Absolute HEP amplitudes did not differ between groups. Nevertheless, healthy individuals showed higher HEPs during the heartbeat perception task than during rest, while no such effect was found in DPD patients (p = .031). DPD patients had higher total levels of salivary alpha-amylase than healthy individuals (9626.6±8200.0 vs. 5344.3±3745.8 kUmin/l; p = .029), but there were no group differences in cardiovascular measures (heart rate: 76.2±10.1 vs. 74.3 ±7.5 bpm, p = .60; nLF HRV: .63±.15 vs. .56 ±.15 n.u., p = .099; LF/HF ratio: 249.3±242.7 vs. 164.8 ±108.8, p = .10), salivary cortisol (57.5±46.7 vs. 55.1±43.6 nmolmin/l, p = .86) or cortisone levels (593.2±260.3 vs. 543.8±257.1 nmolmin/l, p = .52). CONCLUSION: These results suggest altered cortical representation of afferent signals originating from the cardiovascular system in DPD patients, which may be associated with higher sympathetic tone. These findings may reflect difficulties of DPD patients to attend to their actual bodily experiences. [less ▲]

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See detailInterozeption bei Depersonalisations-/Derealisationsstörung: veränderte kortikale Repräsentation afferenter Körpersignale bei intakter Repräsentation auf Hirnstammebene
Schulz, André UL; Matthey, J. H.; Köster, S. et al

in Wittchen, H.-U.; Härtling, S.; Hoyer, J. (Eds.) Abstractband - Wieviel Psychologie steckt in der Psychotherapie? (2015)

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See detailWahrnehmung körperinterner Signale bei Bulimia Nervosa und Binge-Eating-Störung
Van Dyck, Zoé UL; Schulz, André UL; Blechert, J. et al

in Wittchen, H.-U.; Härtling, S.; Hoyer, J. (Eds.) Abstractband - Wieviel Psychologie steckt in der Psychotherapie? (2015)

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See detailInteroception in anorexia nervosa: evidence at cortical and self-report levels
Lutz, Annika UL; Schulz, André UL; Voderholzer, Ulrich et al

in 45th Annual Congress of the European Association for Behavioural and Cognitive Therapies (EABCT) (2015)

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See detailGastrische Modulation der Schreckreaktion: eine prä-attentive Methode zur Abbildung afferenter Signale aus dem gastrointestinalen System
Schulz, André UL; Van Dyck, Zoé UL; Lutz, Annika UL et al

in Kaiser, J.; Fiebach, C. (Eds.) 41. Tagung Psychologie und Gehirn - Abstracts der Beiträge (2015)

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See detailAffektive Bewertung von Körperbildern bei Anorexia nervosa
Lutz, Annika UL; Herbert, C.; Schulz, André UL et al

in Wittchen, H.-U.; Härtling, S.; Hoyer, J. (Eds.) Abstractband - Wieviel Psychologie steckt in der Psychotherapie? (2015)

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See detailBody or cup? Alterations in featural and configural body image processing in anorexia nervosa
Lutz, Annika UL; Herbert, Cornelia; Schulz, André UL et al

in Psychophysiology (2015), 52(supplement 1), 123

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See detailEmotions matter: Affektive und kardiale Modulation der Schreckreaktion
Schaan, Violetta UL; Schächinger, H.; Vögele, Claus UL et al

in Kaiser, J.; Fiebach, C. (Eds.) 41. Tagung Psychologie und Gehirn - Abstracts der Beiträge (2015)

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See detailInterozeptive Sensitivität bei Bulimia Nervosa und Binge-Eating-Störung
Van Dyck, Zoé UL; Schulz, André UL; Blechert, J. et al

in Kaiser, J.; Fiebach, C. (Eds.) 41. Tagung Psychologie und Gehirn - Abstracts der Beiträge (2015)

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See detailShort-term food deprivation increases amplitudes of heartbeat-evoked potentials
Schulz, André UL; Ferreira de Sá, D. S.; Dierolf, Angelika UL et al

in Psychophysiology (2015), 52(5), 695-703

Nutritional state, i.e. fasting or non-fasting, may affect the processing of interoceptive signals, but mechanisms underlying this effect remain unclear. We investigated 16 healthy women on two separate ... [more ▼]

Nutritional state, i.e. fasting or non-fasting, may affect the processing of interoceptive signals, but mechanisms underlying this effect remain unclear. We investigated 16 healthy women on two separate days: when satiated (standardized food intake) and after an 18 h food deprivation period. On both days, heartbeat-evoked potentials (HEPs) and cardiac and ANS activation indices (heart rate, nLF HRV) were assessed. The HEP is an EEG pattern that is considered an index of cortical representation of afferent cardiovascular signals. Average HEP activity (R-wave +455-595 ms) was enhanced during food deprivation compared to normal food intake. Cardiac activation did not differ between nutritional conditions. Our results indicate that short-term food deprivation amplifies an electrophysiological correlate of the cortical representation of visceral-afferent signals originating from the cardiovascular system. This effect could not be attributed to increased cardiac activation, as estimated by heart rate and nLF HRV, after food deprivation. [less ▲]

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See detailZentralnervöse Verarbeitung von Körpersignalen bei Anorexia nervosa
Lutz, Annika UL; Schulz, André UL; Voderholzer, U. et al

in Kaiser, J.; Fiebach, C. (Eds.) 41. Tagung Psychologie und Gehirn - Abstracts der Beiträge (2015)

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See detailGastrisch-evozierte Potenziale: ein neurophysiologischer Indikator für die kortikale Repräsentation afferenter Signale aus dem gastrointestinalen System
Schaan, L.; Van Dyck, Zoé UL; Lutz, Annika UL et al

in Kaiser, J.; Fiebach, C. (Eds.) 41. Tagung Psychologie und Gehirn - Abstracts der Beiträge (2015)

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See detailAcoustic startle reactivity while processing reward related food cues during food deprivation: evidence from women in different menstrual cycle phases and men
Ferreira de Sá, D. S.; Plein, D.; Schulz, André UL et al

in Psychophysiology (2014), 51(2), 159-167

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See detailHeart rate response to post-learning stress predicts memory consolidation
Larra, M. F.; Schulz, André UL; Schilling, T. M. et al

in Neurobiology of Learning & Memory (2014), 109(C), 74-81

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See detailPsychophysiologische Indikatoren für Interozeption: Kognition und Klinik
Schulz, André UL; Bertsch, K.

in Verleger, R.; Krämer, U.; Beyer, F. (Eds.) et al Abstractband 40. Tagung "Psychologie und Gehirn" (2014)

Interozeption – die Wahrnehmung von Körpersignalen – spielt bei vielen psychologischen Prozessen eine wichti-ge Rolle, z.B. beim subjektiven Erleben von Emotionen oder bei der Symptomgenese ... [more ▼]

Interozeption – die Wahrnehmung von Körpersignalen – spielt bei vielen psychologischen Prozessen eine wichti-ge Rolle, z.B. beim subjektiven Erleben von Emotionen oder bei der Symptomgenese körperbezogener psychi-scher Störungen. Neben Herzschlagdetektionstests, die als Indikator für die interozeptive Genauigkeit heran-gezogen werden, existieren außerdem einige psychophy-siologische Methoden für die Erfassung interozeptiver Prozesse, wie Herzschlag-evozierte Potenziale, respira-torische Widerstände oder die Kopplung von Stimulus-präsentation an den kardialen Zyklus. Ziel dieses Sym-posiums ist es, neue Erkenntnisse zu psychophysiolo-gischen Mechanismen von Interozeption zu präsentieren, die auf unterschiedliche viszerale Organe zurückgehen, sowie deren Integration in normales und pathologisches Erleben und Verhalten zu diskutieren. Zunächst wird Thomas M. Schilling (Universität Trier) den Einfluss von baro-afferenter neuronaler Signalüber-mittlung auf die Integration multisensorischer Stimuli diskutieren. Daraufhin präesentiert Sibylle Petersen (KU Leuven) Ergebnisse zu Effekten von Kategorisierung von Atemwiderständen auf Wahrnehmung und Atem-verhalten, sowie Zusammenhang dieser Effekte mit Furcht vor interozeptiven Reizen. Zoé van Dyck (Uni-versität Luxemburg) wird anschließend einen Vortrag zum Einfluss von kurzzeitiger Nahrungsdeprivation auf die Herzschlagdetektionsgenauigkeit halten. Von Laura Müller (Universitätsklinikum Heidelberg) werden Daten zu Herzschlag-evozierten Potenzialen als Indikatoren für die kortikale Verarbeitung afferenter Signale aus dem kardiovaskulären System bei Boderline-Persönlichkeits-störung im Vergleich zu Gesunden präsentiert. Zum Abschluss diskutiert André Schulz (Universität Luxem-burg) Konvergenzen und Divergenzen von interozepti-ven Selbstberichten, Herzschlagdetektionsgenauigkeit und Herzschlag-evozierter Potenziale bei Depersonalisa-tions-/Derealisationsstörung im Vergleich zu Gesunden. [less ▲]

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