References of "Wang, Zheng"
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See detailLearn to Make Decision with Small Data for Autonomous Driving : Deep Gaussian Process and Feedback Control
Fang, Wenqi; Zhang, Shitian; Huang, Hui UL et al

in Journal of Advanced Transportation (2020), 2020

Autonomous driving is a popular and promising field in artificial intelligence. Rapid decision of the next action according to the latest few actions and status, such as acceleration, brake, and steering ... [more ▼]

Autonomous driving is a popular and promising field in artificial intelligence. Rapid decision of the next action according to the latest few actions and status, such as acceleration, brake, and steering angle, is a major concern for autonomous driving. There are some learning methods, such as reinforcement learning which automatically learns the decision. However, it usually requires large volume of samples. In this paper, to reduce the sample size, we exploit the deep Gaussian process, where a regression model is trained on small sample datasets and captures the most significant features correctly. Besides, to realize the real-time and close-loop control, we combine the feedback control into the process. Experimental results on the Torcs simulation engine illustrate smooth driving on virtual road which can be achieved. Compared with the amount of training data in deep reinforcement learning, our method uses only 0.34\% of its size and obtains similar simulation results. It may be useful for real road tests in the future. [less ▲]

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See detailCNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization
Xia, Caihong; Nguyen, Minh Vu Chong UL; Garrison, Amy K. et al

in Developmental Neurobiology (2013), 73(9), 673-687

The peptide hormone CNP has recently been found to positively regulate axon branching and growth via activation of cGMP signaling in embryonic dorsal root ganglion (DRG) neurons, but the cellular ... [more ▼]

The peptide hormone CNP has recently been found to positively regulate axon branching and growth via activation of cGMP signaling in embryonic dorsal root ganglion (DRG) neurons, but the cellular mechanisms mediating the regulation of these developmental processes have not been established. In this study, we provide evidence linking CNP/cGMP signaling to microtubule dynamics via the microtubule regulator CRMP2. First, phosphorylation of CRMP2 can be suppressed by cGMP activation in embryonic DRG neurons, and non-phosphorylated CRMP2 promotes axon branching and growth. In addition, real time analysis of growing microtubule ends indicates a similar correlation of CRMP2 phosphorylation and its activity in promoting microtubule polymerization rates and durations in both COS cells and DRG neuron growth cones. Moreover, direct activation of cGMP signaling leads to increased assembly of dynamic microtubules in DRG growth cones. Finally, low doses of a microtubule depolymerization drug nocodazole block CNP/cGMP-dependent axon branching and growth. Taken together, our results support a critical role of microtubule dynamics in mediating CNP/cGMP regulation of axonal development. © 2013 Wiley Periodicals, Inc. [less ▲]

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