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See detailHumanized mice for modeling human infectious disease: challenges, progress, and outlook.
Legrand, Nicolas; Ploss, Alexander; Balling, Rudi UL et al

in Cell Host and Microbe (2009), 6(1), 5-9

Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and ... [more ▼]

Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases. [less ▲]

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