The new Protein Topology Graph Library web server

in Bioinformatics (2016), 32(3), 474-6

Summary: We present a new, extended version of the Protein Topology Graph Library (PTGL) web server. The PTGL describes the protein topology on the super-secondary structure level. It allows to compute ... [more ▼]

Summary: We present a new, extended version of the Protein Topology Graph Library (PTGL) web server. The PTGL describes the protein topology on the super-secondary structure level. It allows to compute and visualize protein ligand graphs and search for protein structural motifs. The new server features additional information on ligand binding to secondary structure elements (SSEs), increased usability, and an application programming interface (API) to retrieve data, allowing for an automated analysis of protein topology. Availability: The PTGL server is freely available on the web at http://ptgl.uni-frankfurt.de. The website is implemented in PHP, JavaScript, PostgreSQL and Apache. It is supported by all major browsers. The VPLG software that was used to compute the protein ligand graphs and all other data in the database is available under the GNU public license 2.0 from http://vplg.sourceforge.net. [less ▲]