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See detailEtude de differentes methodes pour la mise en evidence des autoanticorps anti-glutamate-decarboxylase associes au developpement du diabete insulinodependant
Humbel, R. L.; Guillaume, A. C.; Schmit, P. et al

in Immuno-Analyse et Biologie Specialisee (1997), 12(5), 275-279

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react ... [more ▼]

Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react predominantly with the native GAD. Various methods have been studied (radio immunoassay [RIA] and enzyme- linked immunosorbent assay [ELISA]). It was observed that at the present time only RIA-tests, in which GAD is presented in fluid phase, are able to detect antibodies. [less ▲]

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