Browse ORBilu by Open Access
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ORBilu is a project developed by
   Controlling complexity: the clinical relevance of mouse complex genetics.; ; et al in European Journal of Human Genetics (2013), 21(11), 1191-6 Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries ... [more ▼] Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches. [less ▲] Detailed reference viewed: 138 (3 UL)The European dimension for the mouse genome mutagenesis program.; ; et al in Nature Genetics (2004), 36(9), 925-7 The European Mouse Mutagenesis Consortium is the European initiative contributing to the international effort on functional annotation of the mouse genome. Its objectives are to establish and integrate ... [more ▼] The European Mouse Mutagenesis Consortium is the European initiative contributing to the international effort on functional annotation of the mouse genome. Its objectives are to establish and integrate mutagenesis platforms, gene expression resources, phenotyping units, storage and distribution centers and bioinformatics resources. The combined efforts will accelerate our understanding of gene function and of human health and disease. [less ▲] Detailed reference viewed: 113 (0 UL) |
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