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See detailPulse transit time is associated with cardiac modulation of startle
Abou Elnaga, Jasmin; Schulz, André UL

in Schächinger, H. (Ed.) Abstractband 43. Tagung Psychologie und Gehirn (2017)

Cardiovascular parameters may have an impact on individual cardioafferent neural traffic which in turn plays a crucial role in emotion and symptom genesis of body-related mental disorders. We investigated ... [more ▼]

Cardiovascular parameters may have an impact on individual cardioafferent neural traffic which in turn plays a crucial role in emotion and symptom genesis of body-related mental disorders. We investigated, whether parameters as heart rate and blood pressure may be determinants of cardiac modulation of startle (CMS), a ―background‖ methodology for assessing baro-afferent signal transmission. Therefore, 30 healthy volunteers received acoustic startle stimuli (105 dB) at 9 different latencies relative to the R-wave (R + 0, 100, 200, 300, 400, 500, 600, 700, and 800 ms; randomized order) after a resting period in which cardiovascular data (Heart rate (HR), heartrate variability (HRV), Pulse transit time (PTT), blood pressure (BP) and blood pressure variability (BPV)) were assessed. We found a strong positive association between CMS and PTT. Stroke volume, which is directly linked to PTT, may have an impact on this relationship, as it does on interoception. We conclude that PTT is associated with cardiac modulation of startle and that stroke volume may play an important role in this relationship. [less ▲]

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