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See detailAbschlussbericht zum Forschungsprojekt "Bewegter Unterricht in Luxemburg"
Bund, Andreas UL; Scheuer, Claude

Report (2017)

Das Konzept der Bewegten Schule geht auf den Schweizer Pädagogen Urs Illi zurück, der es Mitte der achtziger Jahre vor allem für den Primarbereich entwickelte (Illi, 1995). Ausgehend von einer medizinisch ... [more ▼]

Das Konzept der Bewegten Schule geht auf den Schweizer Pädagogen Urs Illi zurück, der es Mitte der achtziger Jahre vor allem für den Primarbereich entwickelte (Illi, 1995). Ausgehend von einer medizinisch-gesundheitlichen (Bewegung als Gesundheitsressource) und entwick-lungs- und lerntheoretischen (Bewegung als zentrales Element der Kindesentwicklung, Bewe-gung als zusätzlicher Sinnes- und Erfahrungskanal) Begründung, geht es in diesem Konzept grundsätzlich darum, mehr Bewegung in die traditionelle „Sitzschule“ zu bringen. Am Projekt „Bewegter Unterricht in Luxemburg“ nahmen die SchülerInnen und Lehrkräfte der Grundschulen in Angelsberg, Larochette, Nommern, Lintgen und Vichten teil. An den Schulen Angelsberg, Larochette und Nommern fand im Untersuchungszeitraum von September 2014 bis Juni 2016 durchgehend Bewegter Unterricht statt. Diese Schulen werden im Weiteren als „Projektschulen“ bezeichnet. An den Schulen in Lintgen und Vichten wurde nicht „bewegt“ unterrichtet; diese Schulen dienten somit als Kontrollschulen. [less ▲]

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See detailExtending the scale of critical housing studies: Towards ‘cross-border gentrification’?
Christmann, Nathalie UL

Scientific Conference (2017, April)

Drawing upon the case of a polycentric cross-border metropolitan region in western Europe, this paper seeks to explore population mobility and housing market developments at the regional/international ... [more ▼]

Drawing upon the case of a polycentric cross-border metropolitan region in western Europe, this paper seeks to explore population mobility and housing market developments at the regional/international scale. Transnational linkages within this cross-border region intensified with the opening of the borders and the economic development of the Grand Duchy of Luxembourg as a global financial centre and a centre for European Institutions. Today about 44 per cent of employees working in Luxembourg live nearby across the Belgian, French or German border. One of the reasons is that housing prices in Luxembourg are nearly twice those in the neighbouring border regions. This increased mobility has an impact on the residents living in these areas. The research that guides this paper aims to detect perceptions of this phenomenon. Therefore principles of municipal policy, urban planning documents and the local media of three medium sized towns in the borderland are reviewed. Following a rather open research concept based on qualitative approaches (discourse analysis, grounded theory), findings reveal that locational advantages such as the proximity to Luxembourg do play a role; the perception that affordable housing is becoming increasingly critical leads to resentments that mix up with national stereotypes; while city officials report displacement due to the border-effect, they also illustrate the opportunities for regional development; at the same time property developers foster the internationalisation of urban planning. Pointing to the relational geographies that link these different places, the paper discusses the pros and cons of an umbrella concept that might be called ‘cross-border gentrification’. [less ▲]

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See detailLa disciplina dei rapporti di lavoro e l'esercizio provvisorio nel fallimento
Ratti, Luca UL; Zoli, Carlo

in Massimario di Giurisprudenza del Lavoro (2017)

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See detailSummary of an Open Discussion on IoT and Lightweight Cryptography
Shamir, Adi; Biryukov, Alex UL; Perrin, Léo Paul UL

in Proceedings of Early Symmetric Crypto workshop, 2017 (2017, April)

This is a summary of the open discussion on IoT security and regulation which took place at the Early Symmetric Crypto (ESC) seminar. Participants have identified that IoT poses critical threat to ... [more ▼]

This is a summary of the open discussion on IoT security and regulation which took place at the Early Symmetric Crypto (ESC) seminar. Participants have identified that IoT poses critical threat to security and privacy. It was agreed that government regulation and dialogue of security researchers with engineers and manufacturers is necessary in order to find proper control mechanisms. [less ▲]

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See detailTopics and Research Directions for Symmetric Cryptography
Biryukov, Alex UL; Daemen, Joan; Lucks, Stefan et al

in Proceedings of Early Symmetric Crypto workshop, 2017 (2017, April)

This is a summary of the open discussion on future research topics for symmetric cryptography chaired by Stefan Lucks. During this session participants were suggesting topics of potential future interest.

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See detailInvestigating Breakdowns in Human Robot Interaction: A Conversation Analysis Guided Single Case Study of a Human-NAO Communication in a Museum Environment
Arend, Béatrice UL; Sunnen, Patrick UL; Caire, Patrice UL

in International Journal of Mechanical, Aerospace, Industrial, Mechatronic and Manufacturing Engineering (2017), 11(5), 839-845

In a single case study, we show how a conversation analysis (CA) approach can shed light onto the sequential unfolding of human-robot interaction. Relying on video data, we are able to show that CA allows ... [more ▼]

In a single case study, we show how a conversation analysis (CA) approach can shed light onto the sequential unfolding of human-robot interaction. Relying on video data, we are able to show that CA allows us to investigate the respective turn-taking systems of humans and a NAO robot in their dialogical dynamics, thus pointing out relevant differences. Our fine grained video analysis points out occurring breakdowns and their overcoming when humans and a NAO-robot engage in a multimodally uttered multi-party communication during a sports guessing game. Our findings suggest that interdisciplinary work opens up the opportunity to gain new insights into the challenging issues of human robot communication in order to provide resources for developing mechanisms that enable complex HRI. [less ▲]

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See detailNEW METHODOLOGY FOR DESIGNING DIRECT-LASER-SINTERED MOTORCYCLE FRAME BASED ON COMBINATION OF TOPOLOGY OPTIMIZATION AND LATTICE IMPLEMENTATION
Cao, Thanh Binh UL; Kedziora, Slawomir UL

in International Journal of Mechanical Engineering (IJME) (2017), 6(3), 39-50

The use of direct laser sintering (DLS) has become more attractive recently since it offers a promising tool in fabricating complex components rapidly. Particularly, the technique is seen more powerful ... [more ▼]

The use of direct laser sintering (DLS) has become more attractive recently since it offers a promising tool in fabricating complex components rapidly. Particularly, the technique is seen more powerful when it is combined with computer-aid design and computational optimization. In spite of knowledge increment in the above areas presently, design method for sophisticated structures towards DLS is still far from being fully exploited. Therefore, this paper was issued to investigate a novel methodology of design, developed by combining topology optimization and lattice-beam implementation, for a blend-solid-lattice frame of a motorcycle. From the obtained results, it was recognized that the as-built tubular hybrid structure demonstrated comparable values of first resonant frequency and mass with respected to those of the original. Additionally, it was found that stiffness of the generated structures depended strongly on locations where lattice was substituted. In particular, less stressed frame’s components were evidenced as appropriate regions for the substitution. The achieved results also revealed estimated buckling load factors, being circa 18 times higher than applied bumping loads acted on the tubular-lattice structure. Finally, equivalent stress predicted in static analyses confirmed all designs working safely in nominated conditions. Based on these achievements, it is believed that the new method worked quite acceptably in designing direct-laser-sintered motorcycle frame, and it is very promising to further develop the method as well as extend it into different complex direct-laser-sintered elements designed for future applications. [less ▲]

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See detailBusiness and Human Rights: Where now?
Baglayan Ceyhan, Basak UL

Presentation (2017, April)

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See detailLa relecture entre pairs en formation doctorale : de l’analyse des commentaires à l’élaboration d’une grille d’accompagnement
Lejot, Eve UL

in LIDIL : Revue de Linguistique et de Didactique des Langues (2017), 55

L’écrit produit dans le contexte universitaire implique un accompagnement pour les étudiants et les doctorants. La relecture entre pairs, inscrite dans les littéracies universitaires, apporte des atouts ... [more ▼]

L’écrit produit dans le contexte universitaire implique un accompagnement pour les étudiants et les doctorants. La relecture entre pairs, inscrite dans les littéracies universitaires, apporte des atouts essentiels de prise de conscience de construction du savoir et de métaréflexion à la familiarisation des normes académiques. Par conséquent, la relecture entre pairs fait partie du programme d’un atelier d’écriture en français proposé semestriellement aux doctorants de l’université du Luxembourg. En appui sur un corpus de commentaires des participants entre eux et sur des questionnaires, ce travail d’analyse débouche sur l’élaboration d’une grille d’évaluation ainsi que sur une réflexion sur l’impact de la relecture entre pairs dans le processus d’écriture des doctorants. [less ▲]

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See detailDynamic change of the human gastrointestinal microbiome in relation to mucosal barrier effects during chemotherapy and immune ablative intervention
Kaysen, Anne UL

Doctoral thesis (2017)

Numerous studies have demonstrated that the gastrointestinal tract (GIT) microbiota plays important roles for the human host. Since the GIT microbiota interfaces with the immune system and represents a ... [more ▼]

Numerous studies have demonstrated that the gastrointestinal tract (GIT) microbiota plays important roles for the human host. Since the GIT microbiota interfaces with the immune system and represents a first line of defense against infectious agents, interest has grown in whether the GIT microbiota may influence the outcome of different anticancer treatments. In this study, the GIT of pediatric patients with different cancer types as well as adult patients with hematologic malignancies undergoing an allogeneic hematopoietic stem cell transplantation were sampled throughout their treatment. In order to deeply profile not only the composition of the community, but also the functional capacity and expression, recently developed wet- and dry-lab methodologies for integrated multi-omic analyses were applied. The trajectories of the prokaryotic and microeukaryotic GIT communities of the patients were described in detail using 16S, 18S rRNA gene amplicon sequencing, as well as metagenomic and metatranscriptomic shotgun sequencing. Indeed, changes in the GIT microbiome in response to treatment were detected. Some changes that are generally thought to be detrimental for human health were detected during treatment, such as a decrease in alpha-diversity, a decrease in relative abundance of bacteria associated with health-promoting properties (such as Blautia spp., Roseburia spp. and Faecalibacterium spp.), as well as an increase in the relative abundance of antibiotic resistance genes. These changes were more pronounced in the adult hematology patients than in the pediatric patients, which is likely due to the more intensive treatment. Some observations need further investigation in order to explain their implication in human health. For example, in the pediatric patients, lower relative abundance of Akkermansia muciniphila was associated with mucositis and functional gene categories that are linked to bacteriophages or the bacterial defense mechanism against bacteriophages were associated with the overall status of the patient and mucositis development. Importantly, in both cohorts, high inter-individual but also high intra-individual variation in the prokaryotic communities were detected while the microeukaryotic community did not exhibit drastic changes. In conclusion, the employed integrated multi-omics analysis allowed detailed profiling of the GIT community including archaea, bacteria, eukaryotes and viruses as well as the functional potential including antibiotic resistance genes. In the future, analysis of the individual-specific processes within the GIT microbial community of patients throughout treatment might allow to adjust therapy regimens accordingly and improve the overall outcome of the therapy. [less ▲]

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See detailOn the consistency between commuting satisfaction and traveling utility: the case of the University of Luxembourg
Sprumont, François UL; Astegiano, Paola; Viti, Francesco UL

in European Journal of Transport and Infrastructure Research (2017), 17(2), 248-262

According to random utility theory, there is no clear distinction between the utility inferred from observed choices (decision utility), the experienced outcome of decision makers’ (experienced utility ... [more ▼]

According to random utility theory, there is no clear distinction between the utility inferred from observed choices (decision utility), the experienced outcome of decision makers’ (experienced utility) or their retrospective evaluation (remembered utility). While empirical experiments have shown that decision utility and remembered utility do not perfectly coincide, little is known regarding the magnitude of this discrepancy, especially in the transport field. Using a cross-sectional travel survey, the objective of this paper is to quantify the relationship between commuters’ stated choice satisfaction (a proxy for remembered utility) and the Logsum function of the utility of all available modes of transport (decision utility). This is of tremendous importance, as implemented transport policy measures, which aim to increase the overall decision makers’ utility, may have low impact on their satisfaction level and thus be ineffective. Results indicate that the utility Logsum is associated with respondents’ commuting satisfaction. However, context specificities have an important impact on this association. [less ▲]

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See detail60 bougies pour un projet impérial original
Scuto, Denis UL

Article for general public (2017)

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See detailSpin texture of two-dimensional topological insulators
Rod, Alexia Nibal UL

Doctoral thesis (2017)

Since the discovery of two-dimensional topological insulators a decade ago, their one-dimensional edge states have attracted significant attention due to their unique properties. For example due to time ... [more ▼]

Since the discovery of two-dimensional topological insulators a decade ago, their one-dimensional edge states have attracted significant attention due to their unique properties. For example due to time-reversal symmetry, they are protected against elastic backscattering and they propagate such that electrons with opposite spins move in opposite directions. In fact, the only necessary symmetry to sustain the edge states is time-reversal symmetry. Moreover in experimental setups, the axial spin symmetry seems to be absent. This absence allows new processes to appear such as inelastic backscattering. However, these consequences were neglected in most theoretical works where the spins are considered to be polarized in the z direction. The aim of this thesis is to provide a more realistic model taking into account a broken axial spin symmetry. In this scheme, we show that a rotation of the spin quantization axis as a function of momentum always appears. This observation leads us to develop a deeper understanding of the size of the rotation related to the material parameters and material models, using also realistic values. It also leads us to understand the implications in real space in cases where translation invariance is lost and how to quantify the rotation in such systems. The new processes which arise when the axial spin symmetry is broken have important consequences for transport in real materials. To see this, we consider a Hall bar with a hole in its middle, i.e. an antidot. This enables us to create two tunneling regions in order to probe the effect of this generic model. We also consider the effect of Coulomb interactions around the hole, as they can be important in such geometry. We discover that it is possible to probe directly the absence of axial spin symmetry. As experimental evidence is important to investigate our theoretical findings, we propose spectroscopic means to probe the spin texture. Finally, we also consider one of the experimentally-known candidate materials, namely InAs/GaSb heterostructures. From the k.p Hamiltonian, it is possible to show that their bandstructure shows some anisotropies. The latter is also reflected in the spin texture of their edge states. [less ▲]

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See detailInvestigation of the Nuclear Function of Tes, an Actin-Binding LIM Protein and Potential Tumor Suppressor
Vaccaroli, Raffaella UL

Doctoral thesis (2017)

The nucleus and the actin cytoskeleton are two distinct components of the eukaryotic cell. While the actin cytoskeleton is a dynamic structure that confers a high degree of cellular mobility as well as a ... [more ▼]

The nucleus and the actin cytoskeleton are two distinct components of the eukaryotic cell. While the actin cytoskeleton is a dynamic structure that confers a high degree of cellular mobility as well as a connection to the extracellular environment, the nucleus contains the genome and is strongly associated with gene expression from the steps of signal transduction to the actual transcription and the resulting translation. Although both components were initially studied separately, the ever-growing knowledge has lately asserted that they are tightly connected. In line, multitude of actin binding proteins were found to have roles in the nucleus, in addition to their well described roles in the cytoplasm. This research work focuses on the actin cytoskeleton protein Tes and its role in the nucleus. Tes is considered as a tumor suppressor protein, since its expression is reduced in different types of cancer cell lines and primary tumors, while its re-expression inhibits various aspects of cancer progression such as invasiveness and metastasis. As a cytoskeletal protein, Tes has been associated with actin polymerization as well as with cell migration and cell spreading. Our results show that, in addition to its cytoplasmic localization, Tes is localized in the nucleus. Artificial size increase of Tes, using a tag based on multiple GFP proteins, allowed us to assign Tes nuclear import to an active mechanism. Through fluorescence microscopy analysis of different modular fragments of Tes, we demonstrated that its PET and LIM1/2 domains are required for its nuclear localization. We also identified a classical monopartite nuclear localization signal (NLS) harbored within its PET domain, required for Tes import in the nucleus. In addition to Tes nuclear import, we also examined its nuclear export. Using the drug Leptomycin B, we demonstrated that Tes nuclear export is active and dependent on the CRM1-export mechanism. By combining protein sequence analysis with point mutations, we identified and characterized the nuclear export signal (NES) at the N-terminus of Tes. Using a photoconvertible probe, we demonstrated the presence of a slower photoconverted fraction of Tes in the nucleus, compared to the more dynamic cytoplasmic fraction. This prompted us to investigate further the existence of potential nuclear partners of Tes. Quantitative mass spectrometry analysis provided evidence for a potential involvement of Tes in nuclear pathways mediating the remodeling of actin, thus suggesting a novel role for Tes in the reorganization of the nuclear actin cytoskeleton. Furthermore, the proteomics studies associated the nuclear localization of Tes with signaling pathways promoting inflammation and cellular death. These results raised the hypothesis that Tes might promote tumor suppression not only through its cytoplasmic functions, but also through these newly described pathways connected to its nuclear localization. Further investigation will be necessary to fully elucidate the function of Tes in the nuclear compartment. [less ▲]

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See detailCross-border evidence gathering: equality of arms within the EU?
van Wijk, Marloes Chantal UL

Doctoral thesis (2017)

The European Union (EU) has set the objective to develop an Area of Freedom, Security and Justice, in which on the one hand freedom of movement is promoted and on the other hand a high level of security ... [more ▼]

The European Union (EU) has set the objective to develop an Area of Freedom, Security and Justice, in which on the one hand freedom of movement is promoted and on the other hand a high level of security is ensured. The EU is therefore adopting measures to enhance international cooperation in criminal matters among the police and judicial authorities of its Member States. The adopted instruments concerning evidentiary matters, such as the gathering, freezing and/or confiscation of information and materials in another EU Member State, seem to serve the main purpose of assisting the authorities in investigating and prosecuting (cross-border) crime. This raises the question to what extent the defence is also given the possibility to gather – or to have gathered – information and materials in another EU Member State with the aim of preparing and presenting its case at trial and, in particular, whether the current (EU) legal framework on cross-border evidence gathering meets the requirements of the principle of equality of arms. This thesis addresses this question by, first of all, discussing the concept of equality of arms, as enshrined in both Article 6 ECHR and Article 47 CFR. It explains to what extent this principle is applicable to cross-border or transnational criminal proceedings and whether it has an autonomous meaning within the EU. In addition, it discusses which requirements can be deduced from the principle in relation to the possibilities of the defence to gather evidence in another EU Member State to prepare and presents its case. Subsequently, the focus is on the development of the European legislation – from both the Council of Europe and the EU – regulating the procedure of cross-border evidence gathering over the last decades. The aim is to explain the position of the defence in this development and to what extent the European legislation gives opportunities to the defence to request the assistance of foreign authorities in obtaining specific information and materials in another EU Member State. In order to understand how the European legislation is applied in practice by the EU Member States, this thesis includes a comparative study of three national jurisdictions: the Netherlands, England and Wales, and Italy. These three jurisdictions each represent a different criminal justice system, either more inquisitorial or adversarial in nature. The comparative study describes how a chosen jurisdiction interprets the principle of equality of arms. Furthermore, it examines to what extent the national jurisdiction allows the defence to carry out independent investigations abroad and how it gives the defence the opportunity to trigger the mechanism of international cooperation and to participate in the requested investigation. Finally, this thesis also includes an analysis of the criminal justice system of the International Criminal Court. In this system evidence gathering depends most of the time on State cooperation and both the Prosecutor and the defence are allowed to conduct independent investigations and seek the assistance of States. It is therefore used as a source of inspiration for potential changes of the EU legislation on cross-border evidence gathering. [less ▲]

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See detailSpeeding-Up Mutation Testing via Data Compression and State Infection
Zhu, Qianqian; Panichella, Annibale UL; Zaidman, Andy

in IEEE International Conference on Software Testing, Verification and Validation Workshops (ICSTW) 2017 (2017, March 13)

Mutation testing is widely considered as a high-end test criterion due to the vast number of mutants it generates. Although many efforts have been made to reduce the computational cost of mutation testing ... [more ▼]

Mutation testing is widely considered as a high-end test criterion due to the vast number of mutants it generates. Although many efforts have been made to reduce the computational cost of mutation testing, its scalability issue remains in practice. In this paper, we introduce a novel method to speed up mutation testing based on state infection information. In addition to filtering out uninfected test executions, we further select a subset of mutants and a subset of test cases to run leveraging data-compression techniques. In particular, we adopt Formal Concept Analysis (FCA) to group similar mutants together and then select test cases to cover these mutants. To evaluate our method, we conducted an experimental study on six open source Java projects. We used EvoSuite to automatically generate test cases and to collect mutation data. The initial results show that our method can reduce the execution time by 83.93% with only 0.257% loss in precision. [less ▲]

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See detailIntegration of the analysis of non-functional properties in Model-Driven Engineering for embedded systems
Brau, Guillaume Sylvain Denis UL

Doctoral thesis (2017)

The engineering of embedded systems relies on two complementary activities: modeling on the one hand enables to represent the system, analysis on the other hand makes it possible to evaluate the various ... [more ▼]

The engineering of embedded systems relies on two complementary activities: modeling on the one hand enables to represent the system, analysis on the other hand makes it possible to evaluate the various non-functional properties (for example, temporal properties with the real-time scheduling analysis). This thesis deals with the integration between these models and analyses: how to apply an analysis on a model? How to manage the analysis process? The first part of this thesis presents a comprehensive approach to answer these questions. This approach is based on four application layers: (1) models to represent the system, (2) accessors to extract data from a model, (3) analyses to compute output data and/or properties from input data (4) contracts to represent the analysis interfaces and orchestrate the analysis process. The second part of this thesis deals with the experimentation of this approach with concrete systems coming from the aerospace: a drone, an exploratory robot and a flight management system. We demonstrate that the accessors enable to apply various real-time scheduling analyses on heterogeneous architectural models, for example written with the industry standard AADL (Architecture Analysis and Design Language) or the new time-triggered language CPAL (Cyber-Physical Action Language). In addition, contracts make it possible to automate complex analysis procedures: which analysis can be applied on a given model? Which are the analyses that meet a given goal? Are there analyses to be combined? Are there interferences between analyses? Etc. [less ▲]

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See detailUn débat parlementaire sur la réduction du temps de travail?
Scuto, Denis UL

in Tageblatt (2017)

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See detailValidating PISA 2015 Collaborative Problem Solving: Report
Schweitzer, Nick UL; Herborn, Katharina UL; Mustafic, Maida UL et al

Presentation (2017, March 01)

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