Reference : Neuropeptides and inflammation: presumed mechanisms in neurogenic inflammation
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/10993/5738
Neuropeptides and inflammation: presumed mechanisms in neurogenic inflammation
English
Landry, Y. [> >]
Bloch, J. G. [> >]
Mousli, M. [> >]
Bueb, Jean-Luc mailto [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
Bronner, C. [> >]
1990
Pathologie et Biologie
Elsevier
38
1
53-6
Yes (verified by ORBilu)
0369-8114
1768-3114
Paris
France
[en] Arthritis ; Humans ; Inflammation ; Mast Cells ; Membrane Proteins ; Neuropeptides ; Substance P ; physiopathology ; physiology
[en] Neuropeptides, among which substance P, VIP (Vasoactive intestinal peptide), somatostatin, neurotensin, dynorphin and enkephalins, are able to modulate inflammatory processes. Increasing interest is now devoted to these peptides in different inflammatory diseases, concerning skin, lung and joins. The effect of substance P can be dependent on its C-terminal moiety implicating by this way an interaction with specific neurokinin receptors or can be dependent on its N-terminal moiety which does not involve a specific membrane receptor. Such diversity of the action mechanisms of peptides should influence the evolution of the anti-inflammatory therapeutic.
http://hdl.handle.net/10993/5738

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