Reference : Integration of proteomic and metabolomic profiling as well as metabolic modeling for ...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/10993/487
Integration of proteomic and metabolomic profiling as well as metabolic modeling for the functional analysis of metabolic networks.
English
May, Patrick mailto [Max Planck Institute for Molecular Plant Physiology > Bioinformatics]
Christian, Nils mailto [Max Planck Institute for Molecular Plant Physiology]
Ebenhoh, Oliver [> >]
Weckwerth, Wolfram [> >]
Walther, Dirk [> >]
2011
Methods in Molecular Biology (Clifton, N.J.)
694
341-63
Yes (verified by ORBilu)
International
1064-3745
United States
[en] Cluster Analysis ; Hordeum/metabolism ; Metabolic Networks and Pathways ; Metabolomics/methods ; Models, Biological ; Proteomics/methods ; Seeds/metabolism ; Software ; Time Factors
[en] The integrated analysis of different omics-level data sets is most naturally performed in the context of common process or pathway association. In this chapter, the two basic approaches for a metabolic pathway-centric integration of proteomics and metabolomics data are described: the knowledge-based approach relying on existing metabolic pathway information, and a data-driven approach that aims to deduce functional (pathway) associations directly from the data. Relevant algorithmic approaches for the generation of metabolic networks of model organisms, their functional analysis, database resources, visualization and analysis tools will be described. The use of proteomics data in the process of metabolic network reconstruction will be discussed.
http://hdl.handle.net/10993/487
10.1007/978-1-60761-977-2_21
http://link.springer.com/protocol/10.1007%2F978-1-60761-977-2_21

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Limited access
Integrated.pdfAuthor preprint145.74 kBRequest a copy

Bookmark and Share SFX Query

All documents in ORBilu are protected by a user license.