Reference : Dynamical binding of proline-rich peptides to their recognition domains
Scientific journals : Other
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/10993/3771
Dynamical binding of proline-rich peptides to their recognition domains
English
Gu, Wei mailto []
Helms, V. [> >]
2005
Biochimica et Biophysica Acta-Proteins and Proteomics
Elsevier Science
1754
1-2
SI
232-238
Yes (verified by ORBilu)
International
1570-9639
Amsterdam
[en] Recognition of proline-rich sequences plays an important role for the assembly of multi-protein complexes during the course of eukaryotic signal transduction and is mediated by a set of protein folds that share characteristic features. For many complex systems containing proline-rich sequences, multiple binding modes have been found by theoretical and/or experimental studies. In this review, we discuss the different binding modes as well as the correlated dynamics of the peptides and their recognition domains, and some implications to their biological functions. Further-more, we give an outlook of the systems in the context of systems biology. (c) 2005 Elsevier B.V. All rights reserved.
http://hdl.handle.net/10993/3771
10.1016/j.bbapap.2005.07.033
JUN 25-29, 2005
4th International Conference on Inhibitors of Protein Kinases (IPK 2005)
Warsaw
POLAND

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Limited access
1-s2.0-S157096390500292X-main.pdfPublisher postprint334.29 kBRequest a copy

Bookmark and Share SFX Query

All documents in ORBilu are protected by a user license.