Reference : Personalized risk prediction of postoperative cognitive impairment - rationale for th...
Scientific journals : Article
Human health sciences : Anesthesia & intensive care
Human health sciences : Multidisciplinary, general & others
Systems Biomedicine
http://hdl.handle.net/10993/37365
Personalized risk prediction of postoperative cognitive impairment - rationale for the EU-funded BioCog project.
English
Winterer, G. [> >]
Androsova, Ganna mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Bender, O. [> >]
Boraschi, D. [> >]
Borchers, F. [> >]
Dschietzig, T. B. [> >]
Feinkohl, I. [> >]
Fletcher, P. [> >]
Gallinat, J. [> >]
Hadzidiakos, D. [> >]
Haynes, J. D. [> >]
Heppner, F. [> >]
Hetzer, S. [> >]
Hendrikse, J. [> >]
Ittermann, B. [> >]
Kant, I. M. J. [> >]
Kraft, A. [> >]
Krannich, A. [> >]
Krause, Roland mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Kuhn, S. [> >]
Lachmann, G. [> >]
van Montfort, S. J. T. [> >]
Muller, A. [> >]
Nurnberg, P. [> >]
Ofosu, K. [> >]
Pietsch, M. [> >]
Pischon, T. [> >]
Preller, J. [> >]
Renzulli, E. [> >]
Scheurer, K. [> >]
Schneider, Reinhard mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Slooter, A. J. C. [> >]
Spies, C. [> >]
Stamatakis, E. [> >]
Volk, H. D. [> >]
Weber, S. [> >]
Wolf, A. [> >]
Yurek, F. [> >]
Zacharias, N. [> >]
2018
European psychiatry : the journal of the Association of European Psychiatrists
50
34-39
Yes (verified by ORBilu)
International
0924-9338
1778-3585
France
[en] Molecular biomarkers ; Multivariate prediction algorithm ; Neuroimaging ; Postoperative cognitive dysfunction ; Postoperative delirium
[en] Postoperative cognitive impairment is among the most common medical complications associated with surgical interventions - particularly in elderly patients. In our aging society, it is an urgent medical need to determine preoperative individual risk prediction to allow more accurate cost-benefit decisions prior to elective surgeries. So far, risk prediction is mainly based on clinical parameters. However, these parameters only give a rough estimate of the individual risk. At present, there are no molecular or neuroimaging biomarkers available to improve risk prediction and little is known about the etiology and pathophysiology of this clinical condition. In this short review, we summarize the current state of knowledge and briefly present the recently started BioCog project (Biomarker Development for Postoperative Cognitive Impairment in the Elderly), which is funded by the European Union. It is the goal of this research and development (R&D) project, which involves academic and industry partners throughout Europe, to deliver a multivariate algorithm based on clinical assessments as well as molecular and neuroimaging biomarkers to overcome the currently unsatisfying situation.
Researchers ; Professionals
http://hdl.handle.net/10993/37365
10.1016/j.eurpsy.2017.10.004
Copyright (c) 2017. Published by Elsevier Masson SAS.
FP7 ; 602461 - BIOCOG - Biomarker Development for Postoperative Cognitive Impairment in the Elderly

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Limited access
Winterer et al. - 2018 - Personalized risk prediction of postoperative cognitive impairment – rationale for the EU-funded BioCog proje.pdfAuthor preprint817.86 kBRequest a copy

Bookmark and Share SFX Query

All documents in ORBilu are protected by a user license.