Reference : Modeling metabolism of the human gut microbiome
Scientific journals : Article
Life sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/35685
Modeling metabolism of the human gut microbiome
English
Magnusdottir, Stefania mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Thiele, Ines mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
2018
Current Opinion in Biotechnology
Elsevier Science
Yes (verified by ORBilu)
International
0958-1669
[en] The human gut microbiome plays an important part in human health. The complexity of the
microbiome makes it difficult to determine the detailed metabolic functions and cross-talk
occurs between the individual species. In silico systems biology studies of the microbiome
can help to identify metabolite exchanges among gut microbes. Constraint-based
reconstruction and analysis methods use biochemically accurate genome-scale metabolic
networks of microorganisms to simulate metabolism between species in a given microbiome
and help generate novel hypotheses on microbial interactions. Here, we review metabolic
modeling studies that have investigated metabolic functions of the gut microbiome.
http://hdl.handle.net/10993/35685
https://www.sciencedirect.com/science/article/pii/S095816691730201X

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