Reference : How to address cellular heterogeneity by distribution biology
Scientific journals : Article
Life sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/33476
How to address cellular heterogeneity by distribution biology
English
Skupin, Alexander mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Komin, Niko mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
May-2017
Current Opinion in Systems Biology
3
154-160
Yes
[en] Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell differentiation. Here, we review recent developments in characterizing cellular heterogeneity by distributions and argue that understanding multicellular life requires the analysis of heterogeneity dy- namics at single cell resolution by integrative approaches that combine methods from non-equilibrium statistical physics, in- formation theory and omics biology.
http://hdl.handle.net/10993/33476
10.1016/j.coisb.2017.05.010
http://dx.doi.org/10.1016/j.coisb.2017.05.010

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