Reference : Late outcomes of drug eluting and bare metal stents in saphenous vein graft percutane...
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/10993/27829
Late outcomes of drug eluting and bare metal stents in saphenous vein graft percutaneous coronary intervention.
English
Nair, Satheesh [> >]
Fath-Ordoubadi, Farzin [> >]
Clarke, Bernard [> >]
El-Omar, Magdi [> >]
Foley, James [> >]
Fraser, Doug G. [> >]
Mahadevan, Vaikom S. [> >]
Neyses, Ludwig mailto [University of Luxembourg > Research Office]
Khattar, Raj S. [> >]
Mamas, Mamas A. [> >]
2011
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
6
8
985-91
Yes (verified by ORBilu)
International
1774-024X
1969-6213
France
[en] Aged ; Angioplasty, Balloon, Coronary/mortality ; Cohort Studies ; Coronary Artery Disease/mortality/therapy ; Drug-Eluting Stents ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Metals ; Middle Aged ; Retreatment/statistics & numerical data ; Retrospective Studies ; Risk Factors ; Saphenous Vein/transplantation ; Treatment Outcome
[en] AIMS: PCI with drug eluting stents (DES) has been shown to reduce restenosis and major adverse cardiac event (MACE) rates compared to bare metal stents (BMS) in native coronary vessels, although outcomes in saphenous vein graft (SVG) lesions are less clear. We retrospectively studied 388 consecutive patients admitted to our centre for SVG PCI to assess mortality and MACE outcomes (defined as composite endpoint of all-death, stroke, myocardial infarction, stent thrombosis and target lesion (TLR)/vessel (TVR) revascularisation) associated with BMS and DES use. METHODS AND RESULTS: Two hundred and nineteen (219) patients had BMS and 169 had DES (total 388 patients). Mean follow up was 41.9+/-23.5 months. No significant differences were observed in mortality (14.2% vs. 11.8%) or MACE (37.6% vs. 35.8%) between the BMS and DES groups at four years follow-up or at other intervening time points studied. Similarly, no differences in TVR/TLR rates were observed over a similar time period (19.8% vs. 21.6%). CONCLUSIONS: We have observed that DES and BMS use in SVG PCI have comparable mortality and MACE rates, and that in contrast to PCI in native coronary arteries, DES do not reduce revascularisation rates in our study cohort.
http://hdl.handle.net/10993/27829
10.4244/EIJV6I8A170
http://www.pcronline.com/eurointervention/34th_issue/170/

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