Reference : Estrogen effects in the heart.
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/10993/27512
Estrogen effects in the heart.
English
Pelzer, T. [> >]
Shamim, A. [> >]
Neyses, Ludwig mailto [University of Luxembourg > Research Office]
1996
Molecular and cellular biochemistry
160-161
307-13
Yes (verified by ORBilu)
International
0300-8177
NETHERLANDS
[en] Animals ; Cardiomegaly/genetics ; Connexin 43/genetics ; Estrogens/physiology ; Female ; Gene Expression Regulation ; Heart/physiology ; Humans ; Hypertension/genetics ; Models, Biological ; Receptors, Estrogen/genetics/physiology ; Signal Transduction
[en] Gender specific differences in cardiovascular disease are largely mediated by sex hormones. The use of estrogens significantly reduces the overall incidence of heart disease in postmenopausal women. Beneficial effects of estrogens on plasma lipoprotein levels are clearly established. However, these do not explain the magnitude of risk reduction seen in clinical studies. Thus additional and currently unknown functions of estrogens must be operative. Elucidation of the exact estrogen action in the heart will have important implications in the treatment of cardiovascular disease. It will probably enhance the therapeutic repertoire in treating heart disease, the most common cause of death in industrialized countries. We will review the current understanding of the function of estrogens in the heart and discuss potential strategies on how to apply these data to clinical practice.
http://hdl.handle.net/10993/27512
10.1007/BF00240064
http://www.ncbi.nlm.nih.gov/pubmed/8901488

There is no file associated with this reference.

Bookmark and Share SFX Query

All documents in ORBilu are protected by a user license.